3-(Trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine photolabels a substrate-binding site of rat hepatic cytochrome P-450 form PB-4

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

The determination of enzyme inhibitor constants

1953 • 4,050 citations

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

1982 • 1,021 citations

Oxygen Activation by Cytochrome P-4501

1980 • 1,013 citations

Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes

1985 • 593 citations

Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

1979 • 576 citations

Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat liver.

1983 • 392 citations

Characterization of a major form of rat hepatic microsomal cytochrome P-450 induced by isoniazid.

1985 • 311 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 294 citations

Biogenesis of peroxisomes: intracellular site of synthesis of catalase and uricase.

1978 • 284 citations

Rat hepatic cytochrome P-450 isoenzyme 2c. Identification as a male-specific, developmentally induced steroid 16 alpha-hydroxylase and comparison to a female-specific cytochrome P-450 isoenzyme.

1984 • 268 citations

Purification, characterization and regulation of five rat hepatic microsomal cytochrome P-450 isozymes

1982 • 265 citations

Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile.

1980 • 256 citations

Selective labeling of the hydrophobic core of membranes with 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine, a carbene-generating reagent

1981 • 230 citations

Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.

1982 • 221 citations

Characterization of Rat‐Liver Microsomal Glutathione S‐Transferase Activity

1980 • 155 citations

Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes.

1983 • 146 citations

The cytochrome P-450 active site. Regiospecificity of prosthetic heme alkylation by olefins and acetylenes.

1983 • 138 citations

Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5

1983 • 132 citations

Properties of electrophoretically homogeneous constitutive forms of liver microsomal cytochrome P-450.

1981 • 121 citations

Studies on the Biosynthesis of Microsomal Membrane Proteins

1982 • 114 citations

Structure of the membrane-embedded F0 part of F1F0 ATP synthase from Escherichia coli as inferred from labeling with 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine

1984 • 102 citations

Purification and characterization of a new form (RLM2) of liver microsomal cytochrome P-450 from untreated rat.

1985 • 85 citations

3-(Trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine, a hydrophobic, photoreactive probe, labels calmodulin and calmodulin fragments in a calcium(2+)-dependent way

1984 • 80 citations

SELECTIVE RELEASE OF CONTENT FROM MICROSOMAL VESICLES WITHOUT MEMBRANE DISASSEMBLY

1974 • 75 citations

Aryl azide photolabels in biochemistry

1980 • 69 citations

Functional and structural polymorphism of rabbit microsomal cytochrome P-450 form 3b.

1982 • 68 citations

The covalent structure of rabbit phenobarbital-induced cytochrome P-450. Partial amino acid sequence and order of cyanogen bromide peptides.

1982 • 63 citations

Hydrophobic labeling, isolation, and partial characterization of the NH2-terminal membranous segment of sucrase-isomaltase complex.

1982 • 62 citations

Labelling the hydrophobic core of membranes

1981 • 61 citations

Membrane protein topology: amino acid residues in a putative transmembrane .alpha.-helix of bacteriorhodopsin labeled with the hydrophobic carbene-generating reagent 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine

1985 • 49 citations

The structure of phenobarbital-inducible rat liver cytochrome P-450 isoenzyme PB-4. Production and characterization of site-specific antibodies.

1985 • 46 citations

Characterization of Rat Cytochrome P-450MC Synthesized in Saccharomyces cerevisiae1

1985 • 45 citations

Membrane topology of light-harvesting protein B870-alpha of Rhodospirillum rubrum G-9+. Amino acid residues in contact with the lipid bilayer as inferred from labeling with photogenerated carbenes.

1985 • 38 citations

Isolation of the hydrophobic membrane binding domain of rat renal gamma-glutamyl transpeptidase selectively labeled with 3-trifluoromethyl-3-(m-[125I]iodophenyl)diazirine.

1982 • 33 citations

Insights into the active site of the cytochrome P-450 haemoprotein family-a unifying concept based on structural considerations

1982 • 33 citations

Comparisons of highly purified hepatic microsomal cytochromes P-450 from holtzman and long-evans rats

1982 • 25 citations

Chemical modification of cytochrome P-450 LM2. Characterization of tyrosine as axial heme iron ligand trans to thiolate.

1984 • 24 citations

The induction of microsomal electron transport enzymes

1983 • 21 citations

Purification and Characterization of Cytochrome P-450 with High Affinity for 7-Alkoxycoumarins1

1984 • 14 citations

Accessibility of proteins in rat liver-free and membrane-bound ribosomes to lactoperoxidase-catalyzed iodination.

1977 • 14 citations

[31] Sucrase-isomaltase of the small-intestinal brush border membrane: Assembly and biosynthesis

1983 • 7 citations