Regioselectivity and stereoselectivity of androgen hydroxylations catalyzed by cytochrome P-450 isozymes purified from phenobarbital-induced rat liver.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or .beta.-naphthoflavone

1982 • 1,021 citations

Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

1979 • 576 citations

Evidence for the participation of cytochrome b5 in hepatic microsomal mixed-function oxidation reactions

1971 • 559 citations

Cholesterol 7α-hydroxylase

1977 • 504 citations

Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms.

1975 • 456 citations

Reconstituted Liver Microsomal Enzyme System That Hydroxylates Drugs, Other Foreign Compounds, and Endogenous Substrates

1972 • 350 citations

Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction.

1981 • 304 citations

Bile Acid Metabolism

1975 • 279 citations

Separation, purification, and characterization of a novel form of hepatic cytochrome P-450 from rats treated with pregnenolone-16 alpha-carbonitrile.

1980 • 256 citations

Increased Activity of Androgen Hydroxylases in Liver Microsomes of Rats Pretreated with Phenobarbital and Other Drugs

1963 • 250 citations

Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.

1982 • 221 citations

Purification and characterization of a minor form of hepatic microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls

1982 • 217 citations

Microsomes, drug oxidations, and drug toxicity

1982 • 187 citations

Self-catalyzed inactivation of hepatic cytochrome P-450 by ethynyl substrates.

1980 • 178 citations

A simple and rapid procedure for the purification of phenobarbitalinducible cytochrome P-450 from rat liver microsomes

1979 • 163 citations

Separation, purification, and properties of multiple forms of cytochrome P-450 from the liver microsomes of phenobarbital-treated mice.

1976 • 159 citations

Regulation of cytochrome P-450. Immunochemical quantitation of eight isozymes in liver microsomes of rats treated with polybrominated biphenyl congeners.

1983 • 132 citations

Immunochemical evidence for induction of a common form of hepatic cytochrome P-450 in rats treated with pregnenolone-16 alpha-carbonitrile or other steroidal or non-steroidal agents.

1982 • 132 citations

Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5

1983 • 132 citations

Inhibition of oxidative drug metabolism in microsomes

1980 • 121 citations

The Involvement of Cytochrome P-450 in Hepatic Microsomal Steroid Hydroxylation Reactions Supported by Sodium Periodate, Sodium Chlorite, and Organic Hydroperoxides

1976 • 115 citations

Chiral sulfoxidations catalyzed by rat liver cytochromes P-450

1982 • 94 citations

Decreased liver cytochrome P-450 in rats caused by norethindrone or ethynyloestradiol

1977 • 91 citations

Selective inactivation of cytochrome P-450 isozymes by suicide substrates

1981 • 89 citations

Studies on the Metabolism of C₁₉‐Steroids in Rat Liver

1968 • 86 citations

Self-catalyzed destruction of cytochrome P-450: covalent binding of ethynyl sterols to prosthetic heme.

1979 • 83 citations

The Roles of Cytochrome b5 in Reconstituted Monooxygenase Systems Containing Various Forms of Hepatic Microsomal Cytochrome P-4501

1981 • 67 citations

Cytochrome b₅ as Electron Donor for Oxy‐cytochrome P‐450

1981 • 62 citations

Michaelis constants for the hydroxylation of steroid hormones and drugs by rat liver microsomes.

1965 • 57 citations

Studies on testosterone hydroxylation and pentobarbital oxidation by rat liver microsomes: Selective effects of age, sex, castration and testosterone propionate treatment

1969 • 51 citations

The steroid 16α-hydroxylase system in mammalian liver

1966 • 49 citations

Testosterone oxidation by rat liver microsomes: Effects of phenobarbital pretreatment and the detection of seven metabolites by HPLC

1981 • 45 citations

Multiplicity of testosterone hydroxylases in a reconstituted hepatic cytochrome P-450 system from uninduced male rats.

1979 • 42 citations

The Action of Lead Tetraacetate on an Enol Acetate. The Epimeric 16-Acetoxy Derivatives of Epiandrosterone Acetate, their Interconversion and Rearrangement

1957 • 40 citations

Effects of drugs and sterols on cholesterol 7 alpha-hydroxylase activity in rat liver microsomes

1983 • 38 citations

Liver microsomal polypeptides from Fischer-344 rats affected by age, sex, and xenobiotic induction

1982 • 36 citations

Rearrangements of Steroidal Ring D Ketols¹

1960 • 30 citations

Induction of testosterone 16β-hydroxylase in rat liver microsomes by phenobarbital pretreatment

1980 • 22 citations

Destruction of highly purified cytochromes P-450 associated with metabolism of fluorinated ether anesthetics

1981 • 20 citations

[40] Steroid hydroxylations catalyzed by cytochrome P-450

1978 • 18 citations

Purification and characterization of taurodeoxycholate 7 alpha-monooxygenase in rat liver.

1981 • 14 citations

Heterogeneity of testosterone hydroxylases in rat and rabbit liver microsomes. Quantification of major hydroxytesterone metabolites by a thin layer radiochromatographic procedure

1980 • 11 citations

Hydroxylierung von Testosteron und 5α-Dihydrotestosteron in Rattenleber. Isolierung von 2α-Hydroxytestosteron

1976 • 4 citations