Two proteins targeted to the same lytic granule compartment undergo very different posttranslational processing.

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1988 • 1,292 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

Constitutive and Regulated Secretion of Proteins

1987 • 1,021 citations

Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas.

1986 • 896 citations

Immunocytochemical localization of galactosyltransferase in HeLa cells: codistribution with thiamine pyrophosphatase in trans-Golgi cisternae.

1982 • 617 citations

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules.

1985 • 398 citations

A family of serine esterases in lytic granules of cytolytic T lymphocytes

1987 • 393 citations

A novel serine esterase expressed by cytotoxic T lymphocytes

1985 • 319 citations

Polarization of the Golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets.

1983 • 294 citations

The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae

1984 • 291 citations

Cloning of a cDNA for a T Cell-Specific Serine Protease from a Cytotoxic T Lymphocyte

1986 • 247 citations

Novel Serine Proteases Encoded by Two Cytotoxic T Lymphocyte-Specific Genes

1986 • 246 citations

Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.

1984 • 219 citations

Proteoglycans in cell-mediated cytotoxicity. Identification, localization, and exocytosis of a chondroitin sulfate proteoglycan from human cloned natural killer cells during target cell lysis.

1985 • 149 citations

Identification of mannose 6-phosphate in glycoproteins that inhibit the assimilation of β-galactosidase by fibroblasts

1979 • 112 citations

Antigen receptor-triggered secretion of a trypsin-type esterase from cytotoxic T lymphocytes.

1987 • 109 citations

Natural killer activity in the rat. III. Characterization of transplantable large granular lymphocyte (LGL) leukemias in the F344 rat.

1984 • 100 citations

Identification and sequencing of cDNA clones encoding the granule-associated serine proteases granzymes D, E, and F of cytolytic T lymphocytes.

1988 • 92 citations

Human large granular lymphocytes and natural killing: Ultrastructural studies of strontium‐induced degranulation

1982 • 76 citations

Biochemical and functional properties of serine esterases in acidic cytoplasmic granules of cytotoxic T lymphocytes.

1987 • 70 citations

Arylsulfatase in natural killer cells: its possible role in cytotoxicity.

1983 • 51 citations

Cloned mouse cells with natural killer function and cloned suppressor T cells express ultrastructural and biochemical features not shared by cloned inducer T cells.

1983 • 51 citations

Direct Analysis of Individual Killer T Cells: Susceptibility of Target Cells to Lysis and Secretion of Hydrolytic Enzymes by CTL

1982 • 51 citations

Electron microscopic study of natural killer cell-tumor cell conjugates

1982 • 34 citations

Intracellular processing of membrane and secreted immunoglobulin delta-chains.

1984 • 32 citations

Cellular localization of perforin 1 in murine cloned cytotoxic T lymphocytes.

1987 • 32 citations

Inhibition of NK and ADCC Activity by Antibodies Against Purified Cytoplasmic Granules From Rat LGL Tumors

1987 • 28 citations

The glycoprotein of VSV accumulates in a distal Golgi compartment in the presence of CCCP

1989 • 15 citations

Acceptor site(s) for T cell-replacing factor (TRF) on B lymphocytes. I. TRF-substituting activity of anti-TRF acceptor site(s) antibody in the triggering of B cells.

1982 • 11 citations

β-Glucuronidase activity in human T and B lymphocytes and the Tμ and Tγ subpopulations

1984 • 5 citations