A family of serine esterases in lytic granules of cytolytic T lymphocytes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Deglycosylation of glycoproteins by trifluoromethanesulfonic acid

1981 • 728 citations

Mechanism of Lymphocyte-Mediated Cytotoxicity

1985 • 602 citations

Electroblotting onto activated glass. High efficiency preparation of proteins from analytical sodium dodecyl sulfate-polyacrylamide gels for direct sequence analysis.

1986 • 440 citations

Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization.

1984 • 329 citations

A novel serine esterase expressed by cytotoxic T lymphocytes

1985 • 319 citations

Isolation of a lytic, pore-forming protein (perforin) from cytolytic T-lymphocytes.

1985 • 300 citations

The Ninth Component of Complement and the Pore-Forming Protein (Perforin 1) from Cytotoxic T Cells: Structural, Immunological, and Functional Similarities

1986 • 272 citations

Cloning of a cDNA for a T Cell-Specific Serine Protease from a Cytotoxic T Lymphocyte

1986 • 247 citations

Novel Serine Proteases Encoded by Two Cytotoxic T Lymphocyte-Specific Genes

1986 • 246 citations

Serine esterase in cytolytic T lymphocytes

1986 • 240 citations

Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.

1984 • 219 citations

A new method for partial peptide mapping using N-chlorosuccinimide/urea and peptide silver staining in sodium dodecyl sulfate-polyacrylamide gels

1982 • 219 citations

Structural/functional similarity between proteins involved in complement- and cytotoxic T-lymphocyte-mediated cytolysis

1986 • 209 citations

The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14

1986 • 197 citations

Formation of transmembrane tubules by spontaneous polymerization of the hydrophilic complement protein C9

1982 • 183 citations

The molecular mechanism of lymphocyte-mediated tumor cell lysis

1985 • 183 citations

The mechanism of cell-mediated cytotoxicity. I. Killing by murine cytotoxic T lymphocytes requires cell surface thiols and activated proteases.

1980 • 155 citations

Granules of cytolytic T-lymphocytes contain two serine esterases.

1986 • 148 citations

Specific release of proteoglycans from human natural killer cells during target lysis

1985 • 146 citations

Mechanisms of Cytotoxicity by NK Cells

1985 • 117 citations

Cell-mediated killing: A common mechanism?

1986 • 114 citations

Effects of N alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes.

1980 • 105 citations

Cloning of two genes that are specifically expressed in activated cytotoxic T lymphocytes.

1986 • 91 citations

Identification of granzyme A isolated from cytotoxic T‐lymphocyte‐granules as one of the proteases encoded by CTL‐specific genes

1986 • 68 citations

Appearance of cytolytic granules upon induction of cytolytic activity in CTL-hybrids.

1985 • 65 citations

Inhibition of the lytic activity of perforin (cytolysin) and of late complement components by proteoglycans

1987 • 46 citations

The mechanism of human NK cell-mediated cytotoxicity. Mode of action of surface-associated proteases in the early stages of the lytic reaction.

1985 • 45 citations

Proteoglycans in secretory granules of NK cells

1986 • 29 citations

Activatable esterase activity of murine natural killer cell-yac tumour cell conjugates

1984 • 29 citations

ROLE OF PROTEASES IN NK ACTIVITY

1985 • 13 citations