Direct Analysis of Individual Killer T Cells: Susceptibility of Target Cells to Lysis and Secretion of Hydrolytic Enzymes by CTL

Quantitative assay of the lytic action of immune lymphoid cells on 51-Cr-labelled allogeneic target cells in vitro; inhibition by isoantibody and by drugs.

1968 • 1,363 citations

Enhancement by Interferon of the Specific Cytotoxicity of Sensitized Lymphocytes

1972 • 308 citations

Studies of allograft immunity in mice. I. Induction, development and in vitro assay of cellular immunity.

1970 • 266 citations

Lymphocyte in vitro cytotoxicity: mechanisms of immune and nonimmune small lymphocyte mediated target L cell destruction

1968 • 230 citations

Mixed Lymphocyte Cultures Produce Effector Cells: Model in vitro for Allograft Rejection

1970 • 230 citations

Spontaneous Cell-Mediated Cytotoxicity in Humans: Role of Interferon and Immunoglobulins

1978 • 213 citations

Ylmphocyte in Vitro Cytotoxicity: Mechanisms of Immune and Non-Immune Small Lymphocyte Mediated Target L Cell Destruction

1968 • 191 citations

Isolation and characterization of individual functionally reactive cytotoxic T lymphocytes: conjugation, killing and recycling at the single cell level

1975 • 158 citations

CELLS MEDIATING SPECIFIC IN VITRO CYTOTOXICITY

1971 • 157 citations

REJECTION OF ASCITES TUMOR ALLOGRAFTS

1972 • 145 citations

Early steps in specific tumor cell lysis by sensitized mouse T lymphocytes. I. Resolution and characterization.

1975 • 137 citations

The Role of Cyclic AMP in the Cytolytic Activity of Lymphocytes

1971 • 130 citations

RECIPROCAL EFFECTS OF cAMP AND cGMP ON MICROTUBULE‐DEPENDENT RELEASE OF LYSOSOMAL ENZYMES*

1975 • 116 citations

Early Steps in Specific Tumor Cell Lysis by Sensitized Mouse T Lymphocytes

1975 • 109 citations

The cytotoxic activity of human natural killer cells requires an intact secretory apparatus

1981 • 91 citations

T-Cell-Mediated Cytolysis: An Overview of Some Current Issues

1977 • 81 citations

YIN/YANG MODULATION OF LYSOSOMAL ENZYME RELEASE FROM POLYMORPHONUCLEAR LEUKOCYTES BY CYCLIC NUCLEOTIDES*

1975 • 72 citations

Studies on the mechanism of T cell-mediated lysis at the single effector cell level. I. Kinetic analysis of lethal hits and target cell lysis in multicellular conjugates.

1979 • 54 citations

Ultrastructural alteration of cytolytic T lymphocytes following their interaction with target cells

1978 • 54 citations

Mechanism of Lymphocyte‐Mediated Cytolysis The LMC Cycle and Its Role in Transplantation Immunity

1973 • 50 citations

Studies on the Mechanism of T Cell-Mediated Lysis at the Single Effector Cell Level

1979 • 44 citations

Presidential address to the American Association of Immunologists, delivered in Chicago, Illinois, April 6, 1977. Mechanism of cytolysis by lymphocytes: A comparison with complement.

1977 • 43 citations

Specificity of Interferon-induced Enhancement of Toxicity for Double-stranded Ribonucleic Acids

1973 • 41 citations

Contemporary Topics in Immunobiology

1977 • 38 citations

Presidential Address to the American Association of Immunologists, Delivered in Chicago, Illinois, April 6, 1977

1977 • 27 citations

The mechanism of T-cell-mediated lysis

1980 • 20 citations

Production of human T-lymphocyte clones. I. Monoclonal culture and functional cytotoxic maturation

1981 • 16 citations

Hormonal protection of interferon‐treated cells against double‐stranded RNA‐induced cytolysis

1979 • 9 citations

Enumeration of T-effector cells mediating direct and/or lectin-dependent lysis

1980 • 7 citations

Evidence for cytotoxic functions in well-defined human T cell clones.

1980 • 4 citations