Interferon messenger RNA is produced constitutively in the organs of normal individuals.

Genomic sequencing.

1984 • 8,343 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Immune Interferon in the Circulation of Patients with Autoimmune Disease

1979 • 907 citations

Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells

1984 • 729 citations

Structure of the human immune interferon gene

1982 • 510 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

The structure of one of the eight or more distinct chromosomal genes for human interferon-α

1980 • 486 citations

Systemic Lupus Erythematosus: Presence in Human Serum of an Unusual Acid-Labile Leukocyte Interferon

1982 • 460 citations

Regulation of human histone gene expression: kinetics of accumulation and changes in the rate of synthesis and in the half-lives of individual histone mRNAs during the HeLa cell cycle.

1983 • 452 citations

Isolation and partial nucleotide sequence of a cDNA clone for human histocompatibility antigen HLA-B by use of an oligodeoxynucleotide primer.

1981 • 374 citations

Antitumor effects of interferon

1978 • 346 citations

Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo.

1985 • 343 citations

Acid-Labile Human Leukocyte Interferon in Homosexual Men with Kaposi's Sarcoma and Lymphadenopathy

1982 • 327 citations

Transcriptional regulation of mouse liver metallothionein-I gene by glucocorticoids

1981 • 284 citations

At Least Three Human Type α Interferons: Structure of α2

1980 • 274 citations

Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells

1985 • 263 citations

Regulation of Human Histone Gene Expression: Kinetics of Accumulation and Changes in the Rate of Synthesis and in the Half-Lives of Individual Histone mRNAs During the HeLa Cell Cycle

1983 • 218 citations

Autocrine β-related interferon controls c-myc suppression and growth arrest during hematopoietic cell differentiation

1986 • 206 citations

Structural relationship of human interferon alpha genes and pseudogenes

1985 • 195 citations

Detection of factors that interact with the human β-interferon regulatory region in vivo by DNAase I footprinting

1986 • 188 citations

Differential expression of human interferon genes

1984 • 184 citations

Induction of a 26-kDa-protein mRNA in human cells treated with an interleukin-1-related, leukocyte-derived factor

1985 • 172 citations

Globin RNA transcription: A possible termination site and demonstration of transcriptional control correlated with altered chromatin structure

1982 • 144 citations

High affinity binding of 125I-labeled mouse interferon to a specific cell surface receptor II. Analysis of binding properties

1981 • 135 citations

Injection of mice with antibody to interferon renders peritoneal macrophages permissive for vesicular stomatitis virus and encephalomyocarditis virus.

1984 • 124 citations

Interferon-induced protein Mx accumulates in nuclei of mouse cells expressing resistance to influenza viruses

1985 • 123 citations

Influence of anti-mouse interferon serum on the growth and metastasis of tumor cells persistently infected with virus and of human prostatic tumors in athymic nude mice

1981 • 112 citations

Not more than 117 base pairs of 5′-flanking sequence are required for inducible expression of a human IFN-α gene

1983 • 98 citations

Injection of mice with antibody to interferon enhances the growth of transplantable murine tumors.

1983 • 94 citations

The Presence of -Interferon in Human Amniotic Fluid

1982 • 90 citations

Mechanism of Interferon Action: Progress toward Its Understanding

1982 • 84 citations

Controlled transcription of a human α-interferon gene introduced into mouse L cells

1982 • 72 citations

Continuous Production of Interferon in Normal Mice: Effect of Anti-interferon Globulin, Sex, Age, Strain and Environment on the Levels of 2-5A Synthetase and p67K Kinase

1985 • 72 citations

Injection of mice with antibody to mouse interferon alpha/beta decreases the level of 2'-5' oligoadenylate synthetase in peritoneal macrophages

1985 • 63 citations

The 5′-flanking region of a human IFN-α gene mediates viral induction of transcription

1983 • 53 citations

Synthesis of Human Interferon β₁ in Escherichia coliInfected by a Lambda Phage Recombinant containing a Human Genomic Fragment

1981 • 42 citations

Multiplication of Poliovirus Type I in Preparations of Human Leukocytes and Its Inhibition by Interferon

1964 • 34 citations

Effect of estrogen on ovalbumin gene expression in differentiated nontarget tissues

1979 • 23 citations

Serum Interferon as a Biological Marker in Malignant Tumors

1985 • 6 citations