Not more than 117 base pairs of 5′-flanking sequence are required for inducible expression of a human IFN-α gene

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

1982 • 1,038 citations

The Interferon System

1979 • 1,035 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

The structure of one of the eight or more distinct chromosomal genes for human interferon-α

1980 • 486 citations

The Interferon System

1979 • 306 citations

Regulation of metallothionein–thymidine kinase fusion plasmids injected into mouse eggs

1982 • 283 citations

DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus.

1981 • 231 citations

In vitro mutagenesis of a circular DNA molecule by using synthetic restriction sites.

1978 • 200 citations

Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them.

1981 • 190 citations

Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter.

1982 • 178 citations

A subcloning strategy for DNA sequence analysis

1980 • 161 citations

Hybrid plasmids containing an active thymidine kinase gene of Herpes simplex virus 1

1979 • 147 citations

Structure of a chromosomal gene for human interferon β

1981 • 133 citations

Human fibroblast interferon gene lacks introns

1981 • 112 citations

DNA Sequence of Two Closely Linked Human Leukocyte Interferon Genes

1981 • 110 citations

Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster

1982 • 97 citations

Structure and expression of human IFN-α genes

1982 • 89 citations

The absence of introns within a human fibroblast interferon gene

1981 • 85 citations

Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells.

1982 • 85 citations

DNA sequence of a major human leukocyte interferon gene.

1981 • 79 citations

Regulated expression of human interferon beta 1 gene after transduction into cultured mouse and rabbit cells.

1982 • 76 citations

Quantitative Determination and Location of Newly Synthesized Virus-Specific Ribonucleic Acid in Chicken Cells Infected with Rous Sarcoma Virus

1973 • 73 citations

Controlled transcription of a human α-interferon gene introduced into mouse L cells

1982 • 72 citations

Inducer-responsive expression of the cloned human interferonβ₁gene introduced into cultured mouse cells

1982 • 70 citations

Nucleotide sequence of the chromosomal gene for human fibroblast (β1) interferon and of the flanking regions

1981 • 67 citations

Inducibility of human β-interferon gene in mouse L-cell clones

1982 • 66 citations

The 5′-flanking region of a human IFN-α gene mediates viral induction of transcription

1983 • 53 citations

Deletion mapping of the inducible promoter of human IFN-β gene

1983 • 43 citations

Cells Persistently Infected with Newcastle Disease Virus

1970 • 38 citations

Inhibition of Host-Cell Protein and Ribonucleic Acid Synthesis by Newcastle Disease Virus

1968 • 33 citations

A Comparison of the Inactivation of Japanese Encephalitis Virus by Deoxycholate and Ether

1968 • 17 citations