Opposite effects of antimicrotubule agents on c-myc oncogene expression depending on the cell lines used

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Apoptotic cell death induced by c-myc is inhibited by bcl-2

1992 • 981 citations

Proteins of the Myc Network: Essential Regulators of Cell Growth and Differentiation

1996 • 787 citations

Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.

1996 • 777 citations

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1995 • 354 citations

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1995 • 276 citations

Taxol induces internucleosomal DNA fragmentation associated with programmed cell death in human myeloid leukemia cells.

1993 • 273 citations

EB1, a protein which interacts with the APC tumour suppressor, is associated with the microtubule cytoskeleton throughout the cell cycle

1998 • 224 citations

Microtubule dynamics: taking aim at a moving target

1995 • 217 citations

Tubulin binds specifically to the signal-transducing proteins, Gs alpha and Gi alpha 1.

1990 • 204 citations

Evidence that microtubule depolymerization early in the cell cycle is sufficient to initiate DNA synthesis

1981 • 202 citations

Activation of p34cdc2 coincident with taxol-induced apoptosis.

1994 • 192 citations

Vinblastine suppresses dynamics of individual microtubules in living interphase cells.

1995 • 161 citations

Microtubule stabilization by taxol inhibits initiation of DNA synthesis by thrombin and by epidermal growth factor

1981 • 157 citations

Taxol, a microtubule-stabilizing antineoplastic agent, induces expression of tumor necrosis factor α and interleukin-1 in macrophages

1992 • 153 citations

IκBα Physically Interacts with a Cytoskeleton-Associated Protein through Its Signal Response Domain

1997 • 144 citations

A far upstream element stimulates c-myc expression in undifferentiated leukemia cells.

1990 • 132 citations

Regulatory elements that modulate expression of human c-myc.

1987 • 129 citations

Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53.

1995 • 120 citations

The N-Terminal Domain of c-Myc Associates with α-Tubulin and Microtubules In Vivo and In Vitro

1995 • 93 citations

Relationship between the structure of taxol and other taxanes on induction of tumor necrosis factor-alpha gene expression and cytotoxicity.

1994 • 91 citations

Piperonyl butoxide and acenaphthylene induce cytochrome P450 1A2 and 1B1 mRNA in aromatic hydrocarbon-responsive receptor knock-out mouse liver.

1996 • 88 citations

Differentiation of human colon cancer cells changes the expression of β-tubulin isotypes and MAPs

1999 • 56 citations

DNA Conformation, Topology, and the Regulation of c-myc Expression

1997 • 32 citations

The ζ Isozyme of Protein Kinase C Binds to Tubulin through the Pseudosubstrate Domain

1997 • 29 citations

Microtubule Polymerization Dynamics, Mitotic Block, and Cell Death by Paclitaxel at Low Concentrations

1994 • 22 citations

Simultaneous combination of microtubule depolymerizing and stabilizing agents acts at low doses

1995 • 17 citations

Pretreatment by Tubulin Agents Decreases C-MYC Induction in Human Colon Carcinoma Cell Line HT29-D4

1997 • 15 citations

Coexpression Pattern of C-MYC Associated Genes in a Small Cell Lung Cancer Cell Line with High Steady State C-MYC Transcription

1995 • 9 citations

Activation of the HIV Type 1 Long Terminal Repeat by X-Irradiation Involves Two Main Rel/NF-κB DNA-Binding Complexes

1996 • 6 citations