Modulation of Calcium Channels by Group I and Group II Metabotropic Glutamate Receptors in Dentate Gyrus Neurons from Patients with Temporal Lobe Epilepsy

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

[6] Correction for liquid junction potentials in patch clamp experiments

1992 • 1,148 citations

Differential Presynaptic Localization of Metabotropic Glutamate Receptor Subtypes in the Rat Hippocampus

1997 • 1,105 citations

Neurotransmitter inhibition of neuronal calcium currents by changes in channel voltage dependence

1989 • 815 citations

Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

1999 • 770 citations

Presynaptic inhibition of elicited neurotransmitter release

1997 • 643 citations

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4

1993 • 585 citations

Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus.

1991 • 431 citations

Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes

1994 • 323 citations

3,5‐Dihydroxyphenylglycine Is a Highly Selective Agonist for Phosphoinositide‐Linked Metabotropic Glutamate Receptors in the Rat Hippocampus

1994 • 270 citations

Metabotropic Glutamate Receptors: Novel Targets for Drug Development

1995 • 261 citations

Modulation of Ca2+ channels by protein kinase C in rat central and peripheral neurons: Disruption of G protein-mediated inhibition

1993 • 211 citations

Cloning and Expression of Rat Metabotropic Glutamate Receptor 8 Reveals a Distinct Pharmacological Profile

1997 • 209 citations

3,5-Dihydroxyphenylglycine

1992 • 195 citations

Surgical Pathology of Temporal Lobe Epilepsy. Experience with 216 Cases

1993 • 190 citations

Activation of group I mG1uRs potentiates NMDA responses in rat hippocampal slices

1996 • 179 citations

A novel class of antagonists for metabotropic glutamate receptors, 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylates

1996 • 178 citations

On the Structure of Ictal Events in Vitro

1996 • 169 citations

Surgical treatment of temporal lobe epilepsy: clinical, radiological, and histopathological findings in 178 patients.

1995 • 168 citations

Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor

1992 • 162 citations

Subdural and depth electrodes in the presurgical evaluation of epilepsy

1994 • 160 citations

Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system

1993 • 144 citations

Surviving Granule Cells of the Sclerotic Human Hippocampus Have Reduced Ca²⁺Influx Because of a Loss of Calbindin-D_28kin Temporal Lobe Epilepsy

2000 • 143 citations

Induction or protection of limbic seizures in mice by mGluR subtype selective agonists

1995 • 140 citations

Voltage‐Activated Calcium Channels: Targets of Antiepileptic Drug Therapy?

1997 • 136 citations

Effects of Phenytoin, Carbamazepine, and Gabapentin on Calcium Channels in Hippocampal Granule Cells from Patients with Temporal Lobe Epilepsy

1998 • 126 citations

Heterologous expression of metabotropic glutamate receptors in adult rat sympathetic neurons: Subtype-specific coupling to ion channels

1995 • 123 citations

Role of Group I Metabotropic Glutamate Receptors in the Patterning of Epileptiform Activities In Vitro

1997 • 120 citations

Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons

1996 • 118 citations

Calcium and epileptogenesis

1986 • 114 citations

Metabotropic glutamate receptor-mediated suppression of L-type calcium current in acutely isolated neocortical neurons

1992 • 111 citations

Pharmacology of postsynaptic metabotropic glutamate receptors in rat hippocampal CA1 pyramidal neurones

1995 • 101 citations

Temporal Lobe Epilepsy Associated Up-Regulation of Metabotropic Glutamate Receptors: Correlated Changes in mGluR1 mRNA and Protein Expression in Experimental Animals and Human Patients

2000 • 101 citations

Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): Phenylglycine derivatives and other selective antagonists—an update

1995 • 99 citations

Metabotropic glutamate receptors coupled to IP3 production mediate inhibition of IAHP in rat dentate granule neurons

1996 • 96 citations

Pharmacological analysis of 4-carboxyphenylglycine derivatives: Comparison of effects on mGluR1α and mGluR5a subtypes

1995 • 91 citations

Hippocampal slices of kindled rats reveal calcium involvement in epileptogenesis

1985 • 89 citations

Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats

1997 • 79 citations

Voltage-dependent Ca2+ currents in epilepsy

1998 • 74 citations

Up-regulation of the metabotropic glutamate receptor mGluR4 in hippocampal neurons with reduced seizure vulnerability

2000 • 74 citations

Electrophysiological diversity of pyramidal‐shaped neurons at the granule cell layer/hilus border of the rat dentate gyrus recorded in vitro

1995 • 72 citations

Changes in Metabotropic Glutamate Receptor mRNA Levels Following Global Ischemia: Increase of a Putative Presynaptic Subtype (mGluR4) in Highly Vulnerable Rat Brain Areas

1994 • 67 citations

Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycine

1998 • 67 citations

Type 4a metabotropic glutamate receptor: identification of new potent agonists and differentiation from the L-(+)-2-amino-4-phosphonobutanoic acid-sensitive receptor in the lateral perforant pathway in rats.

1995 • 64 citations

Rat group I Metabotropic Glutamate Receptors Inhibit Neuronal Ca²⁺Channels via Multiple Signal Transduction Pathways in HEK 293 Cells

1998 • 62 citations

Modulation of calcium channels by metabotropic glutamate receptors in cerebellar granule cells

1995 • 60 citations

(S)‐Carboxy‐3‐Hydroxyphenylglycine, an Antagonist of Metabotropic Glutamate Receptor (mGluR)1a and an Agonist of mGluR2, Protects Against Audiogenic Seizures in DBA/2 Mice

1994 • 59 citations

The modulation of calcium currents by the activation of mGluRs

1996 • 58 citations

Facilitatory coupling between a glutamate metabotropic receptor and dihydropyridine-sensitive calcium channels in cultured cerebellar granule cells

1995 • 51 citations

Pharmacological characterization of MCCG and MAP4 at the mGluR1b, mGluR2 and mGluR4a human metabotropic glutamate receptor subtypes

1995 • 50 citations

Properties of Voltage-Activated Ca²⁺ Currents in Acutely Isolated Human Hippocampal Granule Cells

1997 • 49 citations

Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtype

1997 • 49 citations

Modulation of seizure activity in mice by metabotropic glutamate receptor ligands.

1996 • 47 citations

Modulation of epileptiform activity by metabotropic glutamate receptors in immature rat neocortex

1995 • 44 citations

Potentiating and depressant effects of metabotropic glutamate receptor agonists on high-voltage-activated calcium currents in cultured retinal ganglion neurons from postnatal mice

1994 • 42 citations

Functional coupling of rat group II metabotropic glutamate receptors to an omega-conotoxin GVIA-sensitive calcium channel in human embryonic kidney 293 cells.

1996 • 37 citations

Activation of Metabotropic Glutamate Receptors Modulates the Voltage-Gated Sustained Calcium Current in a Teleost Horizontal Cell

1999 • 33 citations

Metabotropic glutamate receptor modulation of excitotoxicity in the neostriatum: role of calcium channels

1999 • 31 citations

Changes in mRNA for metabotropic glutamate receptors after transient cerebral ischaemia

1994 • 27 citations

Group I Metabotropic Glutamate Receptors Mediate Slow Inhibition of Calcium Current in Neocortical Neurons

1998 • 15 citations

A golgi study of cell types in the dentate gyrus of the adult human brain

1995 • 12 citations