Metabotropic glutamate receptor modulation of excitotoxicity in the neostriatum: role of calcium channels

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS

1997 • 3,070 citations

Functional anatomy of the basal ganglia. I. The cortico-basal ganglia-thalamo-cortical loop

1995 • 2,101 citations

The metabotropic glutamate receptors, MGLUR2 and MGLUR3, show unique postsynaptic, presynaptic and glial localizations

1996 • 584 citations

Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat

1993 • 554 citations

Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat

1994 • 512 citations

Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain

1993 • 415 citations

Excitatory amino acid binding sites in the basal ganglia of the rat: A quantitative autoradiographic study

1992 • 369 citations

The major tyrosine-phosphorylated protein in the postsynaptic density fraction is N-methyl-D-aspartate receptor subunit 2B.

1994 • 314 citations

Dopaminergic Modulation of NMDA-Induced Whole Cell Currents in Neostriatal Neurons in Slices: Contribution of Calcium Conductances

1998 • 290 citations

Pre‐ and postsynaptic glutamate receptors at a giant excitatory synapse in rat auditory brainstem slices.

1995 • 254 citations

Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3

1995 • 238 citations

Distribution of a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat and mouse: an immunohistochemical study with a monoclonal antibody

1998 • 217 citations

Rapid Communication: Ca²⁺ Channel Blockers Attenuate β‐Amyloid Peptide Toxicity to Cortical Neurons in Culture

1994 • 214 citations

Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones

1997 • 211 citations

Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage

1992 • 193 citations

Pre- and postsynaptic localization of a metabotropic glutamate receptor, mGluR2, in the rat brain: an immunohistochemical study with a monoclonal antibody

1996 • 182 citations

Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide.

1995 • 168 citations

The inhibitory mGluR agonist, s-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death

1995 • 165 citations

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

1991 • 161 citations

Activation of Class II or III Metabotropic Glutamate Receptors Protects Cultured Cortical Neurons Against Excitotoxic Degeneration

1995 • 147 citations

Induction or protection of limbic seizures in mice by mGluR subtype selective agonists

1995 • 140 citations

The phosphoprotein DARPP-32 mediates cAMP-dependent potentiation of striatal N -methyl- <scp>d</scp> -aspartate responses

1997 • 138 citations

Excitatory synaptic transmission in neostriatal neurons: regulation by cyclic AMP-dependent mechanisms

1995 • 133 citations

The metabotropic excitatory amino acid receptor agonist 1S,3R-ACPD selectively potentiates N-methyl-D-aspartate-induced brain injury

1992 • 102 citations

In VitroBinding Characteristics of a New Selective Group II Metabotropic Glutamate Receptor Radioligand, [³H]LY354740, in Rat Brain

1998 • 96 citations

Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate receptor activity and prevent neurotoxicity in mesencephalic neurons in vitro.

1995 • 90 citations

Activation of the glutamate metabotropic receptor protects retina against N-methyl-D-aspartate toxicity

1992 • 84 citations

Membrane‐delimited modulation of NMDA currents by metabotropic glutamate receptor subtypes 1/5 in cultured mouse cortical neurons.

1997 • 83 citations

Prolonged anticonvulsant action of glutamate metabotropic receptor agonists in inferior colliculus of genetically epilepsy-prone rats

1997 • 79 citations

DCG‐IV Selectively Attenuates Rapidly Triggered NMDA‐induced Neurotoxicity in Cortical Neurons

1996 • 75 citations

Trans-ACPD depresses synaptic transmission in the hippocampus

1991 • 75 citations

Anticonvulsive and neuroprotective actions of a potent agonist (DCG-IV) for Group II metabotropic glutamate receptors against intraventricular kainate in the rat

1997 • 72 citations

Activation of Multiple Metabotropic Glutamate Receptor Subtypes Prevents NMDA‐induced Excitotoxicity in Rat Hippocampal Slices

1996 • 71 citations

Metabotropic Glutamate Receptors Regulate N-Methyl-<scp>d</scp>-Aspartate–Mediated Synaptic Transmission in Nucleus Accumbens

1997 • 64 citations

Glutamate receptor regulation of rat nucleus accumbens neurons in vivo

1996 • 63 citations

The modulation of calcium currents by the activation of mGluRs

1996 • 58 citations

Metabotropic glutamate receptors modulateN-methyl-d-aspartate receptor function in neostriatal neurons

1994 • 53 citations

Modulation of seizure activity in mice by metabotropic glutamate receptor ligands.

1996 • 47 citations

Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions

1995 • 46 citations

Regulation of N-methyl-D-aspartate-induced toxicity in the neostriatum: a role for metabotropic glutamate receptors?

1996 • 41 citations

Potent, stereoselective, and brain region selective modulation of second messengers in the rat brain by (+)LY354740, a novel group II metabotropic glutamate receptor agonist

1998 • 32 citations

Direct observation of neurotoxicity in brain slices with infrared videomicroscopy

1993 • 32 citations

Glutamate receptor-induced toxicity in neostriatal cells

1996 • 30 citations

Metabotropic glutamate receptor activation selectively limits excitotoxic damage in the intact neostriatum

1996 • 17 citations

Involvement of a cyclic-AMP pathway in group I metabotropic glutamate receptor responses in neonatal rat cortex

1997 • 14 citations