Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): Phenylglycine derivatives and other selective antagonists—an update

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

The metabotropic glutamate receptors: Structure and functions

1995 • 2,269 citations

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

1992 • 814 citations

Metabotropic glutamate receptors in brain function and pathology

1993 • 799 citations

Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate

1993 • 724 citations

Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat

1992 • 645 citations

Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4

1993 • 585 citations

Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction.

1994 • 466 citations

Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors

1990 • 464 citations

THE EFFECTS OF A SERIES OF ω‐PHOSPHONIC α‐CARBOXYLIC AMINO ACIDS ON ELECTRICALLY EVOKED AND EXCITANT AMINO ACID‐INDUCED RESPONSES IN ISOLATED SPINAL CORD PREPARATIONS

1982 • 463 citations

Molecular Diversity and Functions of Glutamate Receptors

1994 • 445 citations

Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes

1994 • 323 citations

Phenylglycine derivatives as antagonists of metabotropic glutamate receptors

1994 • 303 citations

Competitive antagonism at metabotropic glutamate receptors by (S) -4-carboxyphenylglycine and (RS) -α-methyl-4-carboxyphenylglycine

1993 • 219 citations

A novel metabotropic glutamate receptor agonist: marked depression of monosynaptic excitation in the newborn rat isolated spinal cord

1993 • 197 citations

Actions of two new antagonists showing selectivity for different sub‐types of metabotropic glutamate receptor in the neonatal rat spinal cord

1994 • 188 citations

Phenylglycine derivatives discriminate between mGluR1- and mGluR5-mediated responses

1995 • 175 citations

Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system

1993 • 144 citations

Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family

1994 • 139 citations

Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death

1994 • 122 citations

New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord

1995 • 105 citations

Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors

1994 • 95 citations

Stereospecific antagonism by (+)-α-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones

1993 • 93 citations

Pharmacological analysis of 4-carboxyphenylglycine derivatives: Comparison of effects on mGluR1α and mGluR5a subtypes

1995 • 91 citations

Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures.

1994 • 88 citations

Evidence for presynaptic depression of monosynaptic excitation in neonatal rat motoneurones by (1S,3S)‐ and (1S,3R)‐ACPD

1992 • 80 citations

Temporal and Depolarization‐Induced Changes in the Absolute Amounts of mRNAs Encoding Metabotropic Glutamate Receptors in Cerebellar Granule Neurons In Vitro

1994 • 57 citations

Antagonism of the synaptic depressant actions of l-AP4 in the lateral perforant path by MAP4

1995 • 57 citations

The actions of phenylglycine derived metabotropic glutamate receptor antagonists on multiple (1S,3R)-ACPD responses in the rat nucleus of the tractus solitarius

1993 • 43 citations

Inhibition of excitatory amino acid-stimulated phosphoinositide hydrolysis in rat hippocampus by l-aspartate-β-hydroxamate

1992 • 25 citations

4-carboxy-3-hydroxyphenylglycine, an antagonist at type I metabotropic glutamate receptors

1993 • 23 citations

Pharmacological analysis of carboxyphenylglycines at metabotropic glutamate receptors

1994 • 20 citations

Actions of phenylglycine derivatives at L-AP4 receptors in retinal ON bipolar cells

1995 • 16 citations

Competitive Antagonism by Phenylglycine Derivatives at Type 1 Metabotropic Glutamate Receptors

1994 • 15 citations

l-Aspartate-β-hydroxamate exhibits mixed agonist/antagonist activity at the glutamate metabotropic receptor in rat neonatal cerebrocortial slices

1992 • 15 citations