The mechanism of folding of globular proteins. Equilibria and kinetics of conformational transitions of penicillinase from Staphylococcus aureus involving a state of intermediate conformation

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Protein Denaturation

1968 • 2,108 citations

Protein denaturation. C. Theoretical models for the mechanism of denaturation.

1970 • 1,550 citations

The Solubility of Amino Acids and Related Compounds in Aqueous Urea Solutions

1963 • 657 citations

A model for the myosin molecule

1960 • 506 citations

Kinetics and mechanism

1953 • 475 citations

The Effect of Compounds of the Urea-Guanidinium Class on the Activity Coefficient of Acetyltetraglycine Ethyl Ester and Related Compounds¹

1965 • 422 citations

The Solubility of Amino Acids, Diglycine, and Triglycine in Aqueous Guanidine Hydrochloride Solutions

1970 • 352 citations

Interpretation of the Ultraviolet Spectral Changes of Proteins

1960 • 279 citations

Acquisition of Three-Dimensional Structure of Proteins

1973 • 248 citations

Theoretical and experimental studies of conformations of polypeptides

1971 • 219 citations

Denaturation of Bovine Carbonic Anhydrase B by Guanidine Hydrochloride

1973 • 189 citations

Kinetics of unfolding and refolding of proteins

1973 • 173 citations

Analysis of the code relating sequence to conformation in proteins: Possible implications for the mechanism of formation of helical regions

1971 • 154 citations

Experimental Free Energy and Enthalpy of Formation of the α Helix¹

1966 • 146 citations

Kinetics of unfolding and refolding of proteins

1973 • 145 citations

Equilibrium and kinetics of the unfolding of lysozyme (muramidase) by guanidine hydrochloride

1966 • 141 citations

Kinetic Evidence for Incorrectly Folded Intermediate States in the Refolding of Denatured Proteins

1971 • 135 citations

Chemical Structure of Bacterial Penicillinases

1969 • 133 citations

A sequential model of nucleation-dependent protein folding: Kinetic studies of ribonuclease A

1972 • 132 citations

The two-disulphide intermediates and the folding pathway of reduced pancreatic trypsin inhibitor

1975 • 126 citations

Kinetics of unfolding and refolding of proteins

1973 • 119 citations

Helix Probability Profiles of Denatured Proteins and Their Correlation with Native Structures

1970 • 109 citations

The amino acid sequence of Staphylococcus aureus penicillinase

1975 • 98 citations

Logical analysis of the mechanism of protein folding

1974 • 82 citations

An Analysis of Perturbations in the Ultraviolet Absorption Spectra of Proteins and Model Compounds

1968 • 79 citations

Kinetics of Folding of Staphylococcal Nuclease

1970 • 75 citations

The chain length dependence of the conformation for oligomers of <scp>L</scp>‐lysine in aqueous solution: Optical rotatory dispersion studies

1971 • 71 citations

Equilibrium and kinetics of the denaturation of a homogeneous human immunoglobulin light chain

1973 • 71 citations

Biological Macromolecules

1968 • 59 citations

The mechanism of folding of globular proteins. Suitability of a penicillinase from Staphylococcus Aureus as a model for refolding studies

1976 • 59 citations

Ultrasonic Attenuation Measurements in Poly-<scp>l</scp>-Glutamic Acid Solutions

1965 • 57 citations

Conformational studies on modified proteins and peptides. II. Conformation of peptides with intact and overlapping helices obtained by cleavage of myoglobin at proline peptide bonds

1970 • 56 citations

The Stability of the Helical Conformation of Random L-Leucine-L-Glutamic Acid Copolymers in Aqueous Solution¹

1965 • 55 citations

Analysis of the code relating sequence to conformation in globular proteins. Development of a stereochemical alphabet on the basis of intra-residue information

1974 • 43 citations

Nuclear magnetic resonance studies of the unfolding of pancreatic ribonuclease

1975 • 37 citations

Tentative Sequential Model for the Unfolding and Refolding of Staphylococcal Nuclease at High pH

1972 • 35 citations

Denaturation of Proteins: Single or Multiple Step Process?

1969 • 30 citations

Acid Denaturation of Human Carbonic Anhydrase B

1974 • 13 citations

Kinetic determinism of lysozyme folding at high temperatures

1974 • 13 citations