The zinc finger gene Krox20 regulates HoxB2 (Hox2.8) during hindbrain segmentation

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

The Neural Crest

1999 • 2,996 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain

1987 • 1,640 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

The role of the neural crest in patterning of avian cranial skeletal, connective, and muscle tissues

1983 • 852 citations

Segmental patterns of neuronal development in the chick hindbrain

1989 • 840 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions

1990 • 685 citations

Segmental origin and migration of neural crest cells in the hindbrain region of the chick embryo

1991 • 635 citations

Two mouse genes encoding potential transcription factors with identical DNA-binding domains are activated by growth factors in cultured cells.

1988 • 580 citations

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain

1989 • 566 citations

Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6

1992 • 537 citations

Retinoic acid receptors and cellular retinoid binding proteins : II. Their differential pattern of transcription during early morphogenesis in mouse embryos

1991 • 527 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

A distinct Hox code for the branchial region of the vertebrate head

1991 • 503 citations

Interactions and fates of avian craniofacial mesenchyme

1988 • 492 citations

Vital dye analysis of cranial neural crest cell migration in the mouse embryo

1992 • 470 citations

Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo

1992 • 467 citations

Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis

1991 • 443 citations

A gene encoding a protein with zinc fingers is activated during G0/G1 transition in cultured cells.

1988 • 428 citations

Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.

1988 • 384 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

The cellular basis of segmentation in the developing hindbrain

1990 • 358 citations

Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm

1990 • 300 citations

Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression.

1991 • 286 citations

Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice

1989 • 262 citations

Base sequence discrimination by zinc-finger DNA-binding domains

1991 • 261 citations

The serum-inducible mouse gene Krox-24 encodes a sequence-specific transcriptional activator.

1990 • 256 citations

Expression pattern of zebrafish pax genes suggests a role in early brain regionalization

1991 • 255 citations

Patterning the vertebrate head: murine Hox 2 genes mark distinct subpopulations of premigratory and migrating cranial neural crest

1991 • 246 citations

Expression of the mouse labial-Alike homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain

1991 • 239 citations

A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm

1992 • 226 citations

Human Hox-4.2 and Drosophila Deformed encode similar regulatory specificities in Drosophila embryos and larvae

1990 • 225 citations

EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

1991 • 218 citations

Segment-specific expression of a homoeobox-containing gene in the mouse hindbrain

1989 • 214 citations

HOX gene activation by retinoic acid

1991 • 211 citations

Developmental and molecular analysis of Deformed ; a homeotic gene controlling Drosophila head development

1987 • 210 citations

The early response gene NGFI-C encodes a zinc finger transcriptional activator and is a member of the GCGGGGGCG (GSG) element-binding protein family.

1991 • 201 citations

The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene.

1990 • 190 citations

Evolution of the vertebrate Hox homeobox genes

1992 • 179 citations

Deciphering the Hox code: Clues to patterning branchial regions of the head

1991 • 164 citations

Molecular approaches to the segmentation of the hindbrain

1990 • 135 citations

Temporal and regional differences in the expression pattern of distinct retinoic acid receptor-β transcripts in the chick embryo

1991 • 131 citations

Hox Codes and Positional Specification in Vertebrate Embryonic Axes

1992 • 126 citations

Analysis of the murine Hox-2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions.

1992 • 123 citations

Domains of cellular retinoic acid-binding protein I (CRABP I) expression in the hindbrain and neural crest of the mouse embryo

1992 • 118 citations

A homeo domain protein reveals the metameric nature of the developing chick hindbrain.

1990 • 118 citations

Retinoic acid-binding protein, rhombomeres and the neural crest

1991 • 114 citations

Segmental and developmental regulation of a presumptive T-cell oncogene in the central nervous system

1990 • 109 citations

A human HOX4B regulatory element provides head-specific expression in Drosophila embryos

1992 • 100 citations

The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development

1989 • 100 citations

High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene.

1991 • 99 citations

Zinc finger-DNA recognition: analysis of base specificity by site-directed mutagenesis

1992 • 97 citations

Deformed autoregulatory element from Drosophila functions in a conserved manner in transgenic mice

1992 • 71 citations

Mapping cranial neural crest cell migration pathways in mammalian embryos

1987 • 59 citations

Mapping functional regions of the segment-specific transcription factor Krox-20

1992 • 46 citations

Krox-20: A candidate gene for the regulation of pattern formation in the hindbrain

1991 • 24 citations