Sex determination compared in Drosophila and Caenorhabditis

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Animal cytology and evolution

1980 • 2,302 citations

Evolution of sex determining mechanisms

1983 • 1,565 citations

Animal Cytology and Evolution.

1955 • 1,258 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides

1989 • 685 citations

glp-1 Is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

1987 • 684 citations

Sex in flies: the splice of life

1989 • 468 citations

Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins

1988 • 461 citations

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors.

1986 • 427 citations

fog-2, a germ-line-specific sex determination gene required for hermaphrodite spermatogenesis in Caenorhabditis elegans.

1988 • 368 citations

The effect of chromosomal position on the expression of the drosophila xanthine dehydrogenase gene

1983 • 368 citations

SEX AND THE SINGLE CELL. I. ON THE ACTION OF MAJOR LOCI AFFECTING SEX DETERMINATION IN DROSOPHILA MELANOGASTER

1980 • 355 citations

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

1989 • 345 citations

The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster

1988 • 284 citations

The achaete-scute gene complex of Drosophila melanogaster comprises four homologous genes.

1988 • 271 citations

AUTOREGULATORY FUNCTIONING OF A DROSOPHILA GENE PRODUCT THAT ESTABLISHES AND MAINTAINS THE SEXUALLY DETERMINED STATE

1984 • 269 citations

The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein

1988 • 266 citations

Gain-of-Function Mutations of fem-3, a Sex-Determination Gene in Caenorhabditis elegans

1987 • 236 citations

SEX DETERMINATION AND DOSAGE COMPENSATION IN DROSOPHILA MELANOGASTER

1983 • 235 citations

Triploid Intersexes in Drosophila melanogaster

1921 • 235 citations

SEX DETERMINATION IN THE NEMATODE C. ELEGANS: ANALYSIS OF tra-3 SUPPRESSORS AND CHARACTERIZATION OF fem GENES

1986 • 210 citations

A genetic analysis of the sex-determining gene, tra-1, in the nematode Caenorhabditis elegans.

1987 • 196 citations

POLYPLOIDS AND SEX DETERMINATION IN CAENORHABDITIS ELEGANS

1979 • 194 citations

Evidence that sisterless-a and sisterless-b are two of several discrete "numerator elements" of the X/A sex determination signal in Drosophila that switch Sxl between two alternative stable expression states.

1988 • 185 citations

xol-1: A gene that controls the male modes of both sex determination and X chromosome dosage compensation in C. elegans

1988 • 163 citations

Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male drosophila

1988 • 157 citations

The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins

1989 • 156 citations

Caenorhabditis elegans compensates for the difference in X chromosome dosage between the sexes by regulating transcript levels

1986 • 154 citations

The ovo locus is required for sex-specific germ line maintenance in Drosophila.

1987 • 153 citations

NORMAL FEMALE GERM CELL DIFFERENTIATION REQUIRES THE FEMALE X CHROMOSOME TO AUTOSOME RATIO AND EXPRESSION OF SEX-LETHAL IN DROSOPHILA MELANOGASTER

1985 • 149 citations

Cell-autonomous and inductive signals can determine the sex of the germ line of Drosophila by regulating the gene Sxl

1989 • 147 citations

Gene Dosage Compensation in Drosophila Melanogaster

1987 • 134 citations

The achaete-scute complex is expressed in neurogenic regions of Drosophila embryos

1987 • 129 citations

Dosage Compensation in Drosophila: Evidence That daughterless and Sex-lethal Control X Chromosome Activity at the Blastoderm Stage of Embryogenesis

1987 • 122 citations

The Drosophila female-specific sex-determination gene, Sex-lethal, has stage-, tissue-, and sex-specific RNAs suggesting multiple modes of regulation.

1989 • 121 citations

ACTIVITY OF THE SEX-DETERMINING GENE tra-2 IS MODULATED TO ALLOW SPERMATOGENESIS IN THE C. ELEGANS HERMAPHRODITE

1986 • 113 citations

A male-specific lethal mutation in Drosophila melanogaster that transforms sex

1979 • 109 citations

A FEMALE-SPECIFIC LETHAL LESION IN AN X-LINKED POSITIVE REGULATOR OF THE DROSOPHILA SEX DETERMINATION GENE, SEX-LETHAL

1986 • 105 citations

The affairs of daughterless and the promiscuity of developmental regulators

1989 • 97 citations

Genes that implement the hermaphrodite mode of dosage compensation in Caenorhabditis elegans.

1989 • 96 citations

Analysis of the role of tra-1 in germline sex determination in the nematode Caenorhabditis elegans.

1989 • 94 citations

The scute (T4) gene acts as a numerator element of the X:a signal that determines the state of activity of sex-lethal in Drosophila.

1989 • 93 citations

Genetic evidence that the sans fille locus is involved in Drosophila sex determination.

1988 • 91 citations

The Caenorhabditis elegans gene sdc-2 controls sex determination and dosage compensation in XX animals.

1989 • 86 citations

Sex determination in Drosophila: the X-chromosomal gene liz is required for Sxl activity.

1988 • 86 citations

sdc-1: A link between sex determination and dosage compensation in C. elegans

1987 • 80 citations

SEX DETERMINATION AND DOSAGE COMPENSATION IN CAENORHABDITIS ELEGANS

1987 • 80 citations

Molecular cloning and transcript analysis of fem-3, a sex-determination gene in Caenorhabditis elegans.

1988 • 67 citations

The Regulatory Hierarchy Controlling Sex Determination And Dosage Compensation IN

1990 • 64 citations

Somatic and germ-cell sex in mammals

1988 • 63 citations

Primary sex determination in the nematode C. elegans

1987 • 55 citations

The Drosophila white gene: a molecular update

1987 • 49 citations

Sex-specific gene expression in somatic tissues of Drosophila melanogaster

1988 • 41 citations

Evidence for Multiple Sex Factors in the X-Chromosome of Drosophila Melanogaster

1931 • 28 citations

Microinjected DNA from the X Chromosome Affects Sex Determination in Caenorhabditis elegans

1988 • 18 citations

Primary events in C. elegans sex determination and dosage compensation

1988 • 15 citations

X chromosome duplications affect a region of the chromosome they do not duplicate in Caenorhabditis elegans.

1988 • 11 citations

Genetic control of sex determination in the germ line ofCaenorhabditis elegans

1988 • 9 citations