Conformational analysis of peptides corresponding to all the secondary structure elements of protein L B1 domain: Secondary structure propensities are not conserved in proteins with the same fold

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Principles that Govern the Folding of Protein Chains

1973 • 6,771 citations

Calculation of protein extinction coefficients from amino acid sequence data

1989 • 5,198 citations

Dominant forces in protein folding

1990 • 3,682 citations

MLEV-17-based two-dimensional homonuclear magnetization transfer spectroscopy

1985 • 3,603 citations

Funnels, pathways, and the energy landscape of protein folding: A synthesis

1995 • 2,607 citations

Determination of the helix and β form of proteins in aqueous solution by circular dichroism

1974 • 2,040 citations

A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules

1980 • 1,886 citations

Multiple quantum filters for elucidating NMR coupling networks

1982 • 1,780 citations

Structure determination of a tetrasaccharide: transient nuclear Overhauser effects in the rotating frame

1984 • 1,650 citations

How does a protein fold?

1994 • 947 citations

A Novel, Highly Stable Fold of the Immunoglobulin Binding Domain of Streptococcal Protein G

1991 • 794 citations

Folding of immunogenic peptide fragments of proteins in water solution

1988 • 735 citations

Elucidating the folding problem of helical peptides using empirical parameters

1994 • 727 citations

Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide

1992 • 582 citations

Sequential resonance assignments as a basis for determination of spatial protein structures by high resolution proton nuclear magnetic resonance

1982 • 568 citations

Defining Solution Conformations of Small Linear Peptides

1991 • 528 citations

A short linear peptide that folds into a native stable β-hairpin in aqueous solution

1994 • 516 citations

Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications.

1995 • 467 citations

‘Random coil’ 1H chemical shifts obtained as a function of temperature and trifluoroethanol concentration for the peptide series GGXGG

1995 • 467 citations

Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding

1988 • 463 citations

Folding of peptide fragments comprising the complete sequence of proteins

1992 • 391 citations

Stabilization of the ribonuclease S‐peptide α‐helix by trifluoroethanol

1986 • 381 citations

Elucidating the Folding Problem of Helical Peptides using Empirical Parameters. II†. Helix Macrodipole Effects and Rational Modification of the Helical Content of Natural Peptides

1995 • 361 citations

Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG

1995 • 355 citations

Helix-coil transition of the isolated amino terminus of ribonuclease

1971 • 310 citations

De novo design and structural analysis of a model β-hairpin peptide system

1996 • 273 citations

Peptide conformation and protein folding

1993 • 241 citations

Solution conformation of the ferrichromes. VI. Charge relay at the peptide bond. Proton magnetic resonance study of solvation effects on the amide electron density distribution

1975 • 216 citations

NMR evidence of a short linear peptide that folds into a .beta.-hairpin in aqueous solution

1993 • 196 citations

Peptide models of protein folding initiation sites. 1. Secondary structure formation by peptides corresponding to the G- and H-helixes of myoglobin

1993 • 175 citations

Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments

1993 • 169 citations

NMR Solution Structure of the Isolated N-Terminal Fragment of Protein-G B1 Domain. Evidence of Trifluoroethanol Induced Native-Like .beta.-Hairpin Formation

1994 • 168 citations

Folding of peptide fragments comprising the complete sequence of proteins

1992 • 168 citations

A short linear peptide derived from the N-terminal sequence of ubiquitin folds into a water-stable non-native β-hairpin

1995 • 164 citations

Kinetic analysis of folding and unfolding the 56 amino acid IgG-binding domain of streptococcal protein G

1992 • 158 citations

Folding of Protein G B1 Domain Studied by the Conformational Characterization of Fragments Comprising Its Secondary Structure Elements

1995 • 142 citations

Secondary‐structure dependent chemical shifts in proteins

1990 • 140 citations

Local structures in unfolded lysozyme and correlation with secondary structures in the native conformation: Helix‐forming or ‐breaking propensity of peptide segments

1991 • 139 citations

Comparison of the three-dimensional structures of human, yeast, and oat ubiquitin.

1987 • 138 citations

Local Structure Due to an Aromatic-Amide Interaction Observed by 1H-Nuclear Magnetic Resonance Spectroscopy in Peptides Related to the N Terminus of Bovine Pancreatic Trypsin Inhibitor

1993 • 120 citations

Dissecting the Structure of a Partially Folded Protein

1993 • 119 citations

Local Conformations of Peptides Representing the Entire Sequence of Bovine Pancreatic Trypsin Inhibitor and Their Roles in Folding

1993 • 116 citations

Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G

1994 • 115 citations

Conformational investigation of designed short linear peptides able to fold into β-hairpin structures in aqueous solution

1996 • 91 citations

Local versus nonlocal interactions in protein folding and stability – an experimentalist's point of view

1996 • 89 citations

Conformational Analysis of Peptides Corresponding to β-Hairpins and a β-Sheet that Represent the Entire Sequence of the α-Spectrin SH3 Domain

1996 • 83 citations

¹H NMR and CD evidence of the folding of the isolated ribonuclease 50–61 fragment

1987 • 80 citations

Residual helical structure in the C-terminal fragment of cytochrome c

1993 • 74 citations

Peptide models of protein folding initiation sites. 2. The G-H turn region of myoglobin acts as a helix stop signal

1993 • 73 citations

Investigation of the backbone dynamics of the igg‐binding domain of streptococcal protein g by heteronuclear two‐dimensional ¹H‐¹⁵N nuclear magnetic resonance spectroscopy

1994 • 73 citations

Native-like β-hairpin structure in an isolated fragment from ferredoxin: NMR and CD studies of solvent effects on the N-terminal 20 residues

1996 • 73 citations

CD and ¹H‐NMR studies on the conformational properties of peptide fragments from the C‐terminal domain of thermolysin

1993 • 71 citations

Direct evidence for a two‐state protein unfolding transition from hydrogen‐deuterium exchange, mass spectrometry, and NMR

1996 • 71 citations

Analysis of the effect of local interactions on protein stability

1996 • 71 citations

A phage display system for studying the sequence determinants of protein folding

1995 • 69 citations

The Physical Properties of Local Interactions of Tyrosine Residues in Peptides and Unfolded Proteins

1995 • 65 citations

Optimal local propensities for model proteins

1995 • 64 citations

Interactions Responsible for the pH Dependence of the β‐Hairpin Conformational Population Formed by a Designed Linear Peptide

1995 • 61 citations

Nonideality of Water-Hexafluoropropanol Mixtures as Studied by X-Ray Small Angle Scattering

1995 • 60 citations

Helix Stop and Start Signals in Peptides and Proteins

1994 • 60 citations

Conformational‐transitions of bovine pancreatic ribonuclease S‐peptide

1968 • 57 citations

Mapping of the Immunoglobulin Light Chain-binding Site of Protein L

1995 • 55 citations

Structural analysis of peptides encompassing all α-helices of three α/β parallel proteins: Che-Y, flavodoxin and P21-Ras: Implications for α-Helix stability and the folding of α/β parallel proteins

1995 • 53 citations

Proton nuclear magnetic resonance sequential assignments and secondary structure of an immunoglobulin light chain-binding domain of protein L

1993 • 43 citations

Thermodynamic genetics of the folding of the B1 immunoglobulin‐binding domain from streptococcal protein G

1995 • 37 citations

Tendamistat (12–26) fragment

1991 • 35 citations

Helix Stop and Start Signals in Peptides and Proteins The Capping Box does not Necessarily Prevent Helix Elongation

1994 • 31 citations

The distribution of α‐helix propensity along the polypeptide chain is not conserved in proteins from the same family

1995 • 17 citations

Backbone Dynamics of a Domain of Protein L Which Binds to Immunoglobulin Light Chains

1996 • 15 citations