Leishmania donovani lipophosphoglycan causes periphagosomal actin accumulation: correlation with impaired translocation of PKCalpha and defective phagosome maturation

MECHANISMS OF PHAGOCYTOSIS IN MACROPHAGES

1999 • 2,766 citations

Common themes in microbial pathogenicity revisited

1997 • 1,370 citations

Common themes in microbial pathogenicity revisited.

1997 • 782 citations

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin

1992 • 728 citations

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1994 • 676 citations

THE LIPOPHOSPHOGLYCAN OF LEISHMANIA PARASITES

1992 • 473 citations

SIGNALING TO THE ACTIN CYTOSKELETON

1998 • 450 citations

Guidebook to the cytoskeletal and motor proteins

1994 • 374 citations

Phagocytosis by zippers and triggers

1995 • 314 citations

A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages.

1995 • 303 citations

Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasiteLeishmania major

2000 • 298 citations

Inhibition of Phagolysosomal Biogenesis by the Leishmania Lipophosphoglycan

1997 • 281 citations

Multiplication of a Human Parasite ( Leishmania donovani ) in Phagolysosomes of Hamster Macrophages in Vitro

1976 • 274 citations

Use of the green fluorescent protein as a marker in transfected Leishmania

1996 • 255 citations

Stage-Specific Adhesion of Leishmania Promastigotes to the Sandfly Midgut

1992 • 245 citations

Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH

1990 • 234 citations

Cytosolic free calcium elevation mediates the phagosome-lysosome fusion during phagocytosis in human neutrophils.

1990 • 229 citations

Protein Kinase C and the Cytoskeleton

1998 • 194 citations

Epidemiology and ecology of leishmaniasis in Latin-America

1978 • 192 citations

Signal transduction of phagocytosis

1995 • 190 citations

Regulation of the expression of nitric oxide synthase and leishmanicidal activity by glycoconjugates of Leishmania lipophosphoglycan in murine macrophages.

1996 • 188 citations

Ca(2+)-independent F-actin assembly and disassembly during Fc receptor-mediated phagocytosis in mouse macrophages.

1991 • 175 citations

Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes

1999 • 161 citations

A Specialized Pathway Affecting Virulence Glycoconjugates of Leishmania

1995 • 156 citations

Inhibition of macrophage protein kinase C-mediated protein phosphorylation by Leishmania donovani lipophosphoglycan.

1992 • 147 citations

Requirement of lipophosphoglycan for intracellular survival of Leishmania donovani within human monocytes.

1990 • 144 citations

Structure of the major carbohydrate fragment of the Leishmania donovani lipophosphoglycan

1987 • 139 citations

Inhibitory effects on protein kinase C activity by lipophosphoglycan fragments and glycosylphosphatidylinositol antigens of the protozoan parasite Leishmania

1989 • 131 citations

Leishmania donovani lipophosphoglycan selectively inhibits signal transduction in macrophages.

1991 • 130 citations

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages.

1986 • 127 citations

Contractile proteins in leukocyte function.

1983 • 124 citations

MacMARCKS, a novel member of the MARCKS family of protein kinase C substrates

1992 • 120 citations

Leishmania promastigotes require lipophosphoglycan to actively modulate the fusion properties of phagosomes at an early step of phagocytosis

2000 • 114 citations

Regulation of macrophage IL-12 synthesis byLeishmania phosphoglycans

1999 • 92 citations

Actin dynamics in human neutrophils during adhesion and phagocytosis is controlled by changes in intracellular free calcium.

1993 • 88 citations

The MARCKS family of protein kinase-C substrates

1995 • 80 citations

Transbilayer inhibition of protein kinase C by the lipophosphoglycan from Leishmania donovani.

1996 • 79 citations

Expression of a repeating phosphorylated disaccharide lipophosphoglycan epitope on the surface of macrophages infected with Leishmania donovani

1990 • 78 citations

Effect of glycolipids of Leishmania parasites on human monocyte activity. Inhibition by lipophosphoglycan.

1990 • 68 citations

The E. Donnall Thomas Lecture, 1993. The machinery of blood cell movements

1994 • 65 citations

Potent inhibition of viral fusion by the lipophosphoglycan of Leishmania donovani

1995 • 62 citations

Role of protein kinase C-alpha in the control of infection by intracellular pathogens in macrophages.

1999 • 57 citations

Lipophosphoglycan fromLeishmaniasuppresses agonist-induced interleukin 1β gene expression in human monocytes via a unique promoter sequence

1996 • 47 citations

Role of Protein Kinase C-α in the Control of Infection by Intracellular Pathogens in Macrophages

1999 • 45 citations

The Lipophosphoglycan of Leishmania Parasites

1992 • 43 citations

Guidebook to the cytoskeletal and motor proteins

1994 • 17 citations

Lipophosphoglycan of Leishmania donovani inhibits lipid vesicle fusion induced by the N‐terminal extremity of viral fusogenic Simian immunodeficiency virus protein

1998 • 16 citations

Lipophosphoglycan traffic and degradation in Leishmania-infected macrophages

1999 • 4 citations