Antigen‐presenting Function of the TL Antigen and Mouse CD1 Molecules

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

1994 • 1,044 citations

Recognition of a lipid antigen by CD1-restricted αβ+ T cells

1994 • 976 citations

Empty MHC class I molecules come out in the cold

1990 • 933 citations

Mice lacking MHC class II molecules

1991 • 869 citations

Crystal Structures of Two Viral Peptides in Complex with Murine MHC Class I H-2K ^b

1992 • 864 citations

CD1-Restricted T Cell Recognition of Microbial Lipoglycan Antigens

1995 • 751 citations

Emerging Principles for the Recognition of Peptide Antigens by MHC Class I Molecules

1992 • 730 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2

1990 • 527 citations

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

1992 • 522 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

A Subset of CD4 ⁺ Thymocytes Selected by MHC Class I Molecules

1994 • 464 citations

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

1990 • 445 citations

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1988 • 445 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

NK susceptibility varies inversely with target cell class I HLA antigen expression.

1987 • 433 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

Promiscuous and allele-specific anchors in HLA-DR-binding peptides

1993 • 383 citations

The Role of the Major Histocompatibility Complex in Immunobiology

1981 • 361 citations

Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor

1994 • 320 citations

The human class II MHC protein HLA-DR1 assembles as empty αβ heterodimers in the absence of antigenic peptide

1992 • 306 citations

Targeting of membrane proteins to endosomes and lysosomes

1994 • 304 citations

A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6

1986 • 297 citations

Ham-2 corrects the class I antigen-processing defect in RMA-S cells

1992 • 289 citations

Two classes of CD1 genes

1989 • 261 citations

Oligoclonal Expansion and CD1 Recognition by Human Intestinal Intraepithelial Lymphocytes

1991 • 243 citations

Expression of Murine CD1 on Gastrointestinal Epithelium

1990 • 231 citations

Antigenic Properties of Experimental Leukemias. I. Serological Studies <italic>In Vitro</italic> With Spontaneous and Radiation-Induced Leuke-mias<xref ref-type="fn" rid="FN2">2</xref>

1963 • 225 citations

Identification of a motif for HLA-DR1 binding peptides using M13 display libraries.

1992 • 224 citations

Peptide-induced conformational change of the class I heavy chain

1991 • 221 citations

Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes

1989 • 217 citations

Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells

1989 • 215 citations

Isolation of CD1 genes: a family of major histocompatibility complex-related differentiation antigens.

1986 • 190 citations

Expression of the thymus leukemia antigen in mouse intestinal epithelium.

1990 • 161 citations

Class I dependence of the development of CD4+ CD8- NK1.1+ thymocytes.

1994 • 155 citations

β ₂ -Microglobulin-Independent MHC Class Ib Molecule Expressed by Human Intestinal Epithelium

1994 • 154 citations

Role of beta2-microglobulin in the intracellular transport and surface expression of murine class I histocompatibility molecules

1989 • 153 citations

Molecules Related to Class-I Major Histocompatibility Complex Antigens

1990 • 146 citations

Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cells.

1992 • 143 citations

Mouse CD1 is distinct from and co-exists with TL in the same thymus.

1988 • 141 citations

NK1.1+ thymocytes. Adult murine CD4-, CD8- thymocytes contain an NK1.1+, CD3+, CD5hi, CD44hi, TCR-V beta 8+ subset.

1990 • 141 citations

Maternally Transmitted Antigen of Mice: A Model Transplantation Antigen

1991 • 141 citations

Activated CD8 binding to class I protein mediated by the T-cell receptor results in signalling

1990 • 136 citations

The fate of CD4-8- T cell receptor-alpha beta+ thymocytes.

1991 • 129 citations

Intestinal intraepithelial lymphocytes are activated and cytolytic but do not proliferate as well as other T cells in response to mitogenic signals.

1993 • 117 citations

Highly restricted expression of the thymus leukemia antigens on intestinal epithelial cells.

1991 • 112 citations

Major histocompatibility complex (MHC)-encoded HAM2 is necessary for antigenic peptide loading onto class I MHC molecules.

1992 • 111 citations

Structure of a gene encoding a murine thymus leukemia antigen, and organization of Tla genes in the BALB/c mouse.

1985 • 111 citations

Role of beta 2-microglobulin in the intracellular transport and surface expression of murine class I histocompatibility molecules.

1989 • 108 citations

ANALYSIS OF THE EFFECTOR FUNCTIONS OF DIFFERENT POPULATIONS OF MUCOSAL LYMPHOCYTES*

1983 • 107 citations

Characterization of a TL−variant of a homozygous TL+ mouse lymphoma

1976 • 101 citations

Isolation and expression of cDNA encoding the murine homologues of CD1.

1991 • 99 citations

Requirement for CD8-major histocompatibility complex class I interaction in positive and negative selection of developing T cells.

1992 • 93 citations

Antigens Specified by the Tla Locus Are Expressed on the Surface of Murine Langerhans Cells

1983 • 92 citations

Co-engagement of CD8 with the T cell receptor is required for negative selection

1991 • 85 citations

Positive selection of invariant V alpha 14+ T cells by non-major histocompatibility complex-encoded class I-like molecules expressed on bone marrow-derived cells.

1995 • 84 citations

Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules

1991 • 81 citations

Technical analysis of IIASA energy scenarios

1984 • 80 citations

Nonclassical behavior of the thymus leukemia antigen: peptide transporter-independent expression of a nonclassical class I molecule.

1995 • 65 citations

Proliferative properties of murine intestinal intraepithelial lymphocytes (IEL): IEL expressing TCRαβ or TCRτδ are largely unresponsive to proliferative signals mediated via conventional stimulation of the CD3-TCR complex

1991 • 61 citations

Evolutionary origin and diversification of the mammalian CD1 antigen genes.

1991 • 51 citations

The thymus leukemia antigen binds human and mouse CD8.

1991 • 39 citations

Murine intestinal intraepithelial lymphocytes. II. Comparison of freshly isolated and cultured intraepithelial lymphocytes

1985 • 35 citations

TL antigen as a transplantation antigen recognized by TL-restricted cytotoxic T cells.

1994 • 34 citations

The biochemical genetics of the Qa-Tla region.

1983 • 20 citations

The alpha 3 domain of the Qa-2 molecule is defective for CD8 binding and cytotoxic T lymphocyte activation.

1993 • 19 citations

An unusual class II molecule

1992 • 19 citations

A system of alloantigens that selectively identifies lymph-node lymphocytes

1982 • 16 citations

Analysis of MHC class I gene expression in adult bone marrow and fetal liver of the BALB/c mouse.

1991 • 8 citations

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