Negative and positive selection of antigen-specific cytotoxic T lymphocytes affected by the α3 domain of MHC I molecules

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1988 • 671 citations

CD8 is needed for development of cytotoxic T but not helper T cells

1991 • 528 citations

A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2

1990 • 527 citations

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1988 • 445 citations

Biochemical characterization and cellular distribution of a polymorphic, murine cell-surface glycoprotein expressed on lymphoid tissues

1982 • 359 citations

A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes

1989 • 339 citations

Induction of classical transplantation tolerance in the adult.

1989 • 325 citations

Deletion of autospecific T cells in T cell receptor (TCR) transgenic mice spares cells with normal TCR levels and low levels of CD8 molecules.

1989 • 231 citations

Clonal Heterogeneity in the Functional Requirement for Lyt‐2/3 Molecules on Cytolytic T Lymphocytes (CTL): Possible Implications for the Affinity of CTL Antigen Receptors

1982 • 204 citations

Inability of CD8α′polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo

1989 • 183 citations

Peptide ligand-induced conformation and surface expression of the Ld class I MHC molecule

1990 • 155 citations

Molecules Related to Class-I Major Histocompatibility Complex Antigens

1990 • 146 citations

The specific binding of peptide ligand to Ld class I major histocompatibility complex molecules determines their antigenic structure.

1991 • 122 citations

Correlation between CD8 dependency and determinant density using peptide-induced, Ld-restricted cytotoxic T lymphocytes.

1991 • 117 citations

Phenotypic identification of memory cytolytic T lymphocytes in a subset of Lyt-2+ cells.

1987 • 110 citations

The Lyt-2 molecule recognizes residues in the class I alpha 3 domain in allogeneic cytotoxic T cell responses.

1988 • 88 citations

Participation of CD4 coreceptor molecules in T-cell repertoire selection

1991 • 85 citations

Development of CD4−CD8+ cytotoxic T cells requires interactions with class I MHC determinants

1988 • 76 citations

CD8 is required during positive selection of CD4-/CD8+ T cells.

1990 • 65 citations

A nonstructural polypeptide encoded by immediate-early transcription unit 1 of murine cytomegalovirus is recognized by cytolytic T lymphocytes.

1987 • 61 citations

Antigen‐presenting Cells for CD8+ T Cells

1990 • 60 citations

The Q7 alpha 3 domain alters T cell recognition of class I antigens.

1991 • 19 citations

Clonal analysis of the anti-Qa-1 cytotoxic T lymphocyte repertoire: definition of the Qa-1d and Qa-1c alloantigens and cross-reactivity with H-2.

1986 • 10 citations