Activated CD8 binding to class I protein mediated by the T-cell receptor results in signalling

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

1984 • 884 citations

Regulation of transmembrane signaling by receptor phosphorylation

1987 • 678 citations

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1989 • 671 citations

Enhancement of LFA-1-mediated cell adhesion by triggering through CD2 or CD3 on T lymphocytes

1989 • 482 citations

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1988 • 445 citations

Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens.

1982 • 306 citations

Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor

1987 • 265 citations

Aggregation of complement receptors on human neutrophils in the absence of ligand.

1987 • 250 citations

Surface Structures Involved in Target Recognition by Human Cytotoxic T Lymphocytes

1982 • 238 citations

Significance of Lyt phenotypes: Lyt2 antibodies block activities of T cells that recognize class 1 major histocompatibility complex antigens regardless of their function.

1981 • 234 citations

LFA-1 and other accessory molecules functioning in adhesions of T and B lymphocytes

1987 • 223 citations

Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes

1987 • 220 citations

Cytotoxic T cells: Lyt phenotype and blocking of killing activity by Lyt antisera

1979 • 208 citations

Clonal Heterogeneity in the Functional Requirement for Lyt‐2/3 Molecules on Cytolytic T Lymphocytes (CTL): Possible Implications for the Affinity of CTL Antigen Receptors

1982 • 204 citations

Transfection of the CD8 gene enhances T-cell recognition

1987 • 177 citations

Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen.

1986 • 159 citations

The role of CD4 in T-cell activation: accessory molecule or co-receptor?

1989 • 134 citations

Cross‐linking of the T cell receptor complex with the subset‐specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cells

1987 • 117 citations

Antigen receptor-triggered secretion of a trypsin-type esterase from cytotoxic T lymphocytes.

1987 • 109 citations

Direct evidence for binding of CD8 to HLA class I antigens.

1989 • 103 citations

Phosphorylation of CD4 and CD8 molecules following T cell triggering.

1987 • 87 citations

Coaggregation of the T-cell receptor with CD4 and other T-cell surface molecules enhances T-cell activation.

1987 • 71 citations

Molecular interactions required for triggering alloantigen-specific cytolytic T lymphocytes.

1989 • 68 citations

Quantitative measurements of the specificity and kinetics of conjugate formation between cloned cytotoxic T lymphocytes and splenic target cells by dual parameter flow cytometry.

1985 • 51 citations

The single-cell assay in cell-mediated cytotoxicity

1983 • 49 citations

Solid-phase binding of class I and II MHC proteins: Immunoassay and T cell recognition

1989 • 35 citations

T cell recognition of nonpolymorphic determinants on H-2 class I molecules.

1988 • 17 citations

Class I alloantigen is sufficient for cytolytic T lymphocyte binding and transmembrane signaling

1988 • 16 citations

Major histocompatibility complex class I-specific cytolytic T cells, derived from gld mice, lacking Thy-1, CD4, and CD8.

1989 • 15 citations