Should we treat the brain in glaucoma?

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

2006 • 5,824 citations

Reduction of Intraocular Pressure and Glaucoma Progression

2002 • 3,029 citations

The advanced glaucoma intervention study (AGIS): 7. the relationship between control of intraocular pressure and visual field deterioration

2000 • 2,619 citations

Primary open-angle glaucoma

2004 • 2,054 citations

Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

2000 • 1,526 citations

Comparison of glaucomatous progression between untreated patients with normal-tension glaucoma and patients with therapeutically reduced intraocular pressures

1998 • 1,525 citations

Neuronal death in glaucoma

1999 • 762 citations

The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis

2006 • 449 citations

Glaucoma as a neurodegenerative disease

2007 • 402 citations

Human glaucoma and neural degeneration in intracranial optic nerve, lateral geniculate nucleus, and visual cortex

2006 • 401 citations

Effects of retinal ganglion cell loss on magno-, parvo-, koniocellular pathways in the lateral geniculate nucleus and visual cortex in glaucoma

2003 • 367 citations

Loss of Neurons in Magnocellular and Parvocellular Layers of the Lateral Geniculate Nucleus in Glaucoma

2000 • 306 citations

Excitotoxicity and nitric oxide in parkinson's disease pathogenesis

1998 • 285 citations

Induction of nitrotyrosine-like immunoreactivity in the lower motor neuron of amyotrophic lateral sclerosis

1995 • 266 citations

Experimental glaucoma and cell size, density, and number in the primate lateral geniculate nucleus.

2000 • 253 citations

The Molecular Basis of Memantine Action in Alzheimers Disease and Other Neurologic Disorders: Low-affinity, Uncompetitive Antagonism

2005 • 249 citations

Efficacy and Safety of Memantine Treatment for Reduction of Changes Associated with Experimental Glaucoma in Monkey, II: Structural Measures

2004 • 211 citations

Atrophy of relay neurons in magno- and parvocellular layers in the lateral geniculate nucleus in experimental glaucoma.

2001 • 205 citations

Nitric Oxide

1999 • 191 citations

A 24-Week Open-Label Extension Study of Memantine in Moderate to Severe Alzheimer Disease

2006 • 187 citations

Lateral Geniculate Nucleus in Glaucoma

1993 • 186 citations

Role of nitric oxide in Parkinson's disease

2005 • 177 citations

CHANGES IN SIZES OF CORTICAL AND LOWER MOTOR NEURONS IN AMYOTROPHIC LATERAL SCLEROSIS

1991 • 173 citations

Outcomes of Trabeculectomy for Primary Open-angle Glaucoma

1995 • 165 citations

The benefit of early trabeculectomy versus conventional management in primary open angle glaucoma relative to severity of disease

1989 • 149 citations

Structure–Function Relations of Parasol Cells in the Normal and Glaucomatous Primate Retina

2005 • 144 citations

A Ten-year Follow-up on a Prospective, Randomized Trial of Postoperative Corticosteroids after Trabeculectomy

1995 • 138 citations

Chronic ocular hypertension induces dendrite pathology in the lateral geniculate nucleus of the brain

2006 • 121 citations

Retinotopic organization of primary visual cortex in glaucoma: Comparing fMRI measurements of cortical function with visual field loss

2006 • 121 citations

Memantine Protects Neurons From Shrinkage in the Lateral Geniculate Nucleus in Experimental Glaucoma

2006 • 118 citations

Transneuronal Degeneration in the Spread of Alzheimer's Disease Pathology: Immunohistochemical Evidence for the Transmission of Tau Hyperphosphorylation

1997 • 98 citations

Glaucoma in primates: cytochrome oxidase reactivity in parvo- and magnocellular pathways.

2000 • 91 citations

Experimental glaucoma in primates: changes in cytochrome oxidase blobs in V1 cortex.

2001 • 84 citations

Laser-Induced Primate Glaucoma

1984 • 82 citations

Magnocellular and parvocellular visual pathways are both affected in a macaque monkey model of glaucoma

1997 • 77 citations

Neurochemical Correlates of Cortical Plasticity after Unilateral Elevated Intraocular Pressure in a Primate Model of Glaucoma

2003 • 72 citations

Lateral geniculate nucleus: anatomic and functional identification by use of MR imaging.

2001 • 63 citations

From benefit to damage. Glutamate and advanced glycation end products in Alzheimer brain

2006 • 56 citations

Oxidative injury by peroxynitrite in neural and vascular tissue of the lateral geniculate nucleus in experimental glaucoma

2004 • 55 citations

Histomorphometric Analysis of Optic Nerve Changes in Experimental Glaucoma

1999 • 46 citations

Depth perception deficits in glaucoma suspects

2006 • 35 citations

Glaucoma and the Brain

2001 • 34 citations