Coupling of an endogenous 5‐HT_1B‐like receptor to increases in intracellular calcium through a pertussis toxin‐sensitive mechanism in CHO‐K1 cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity

2012 • 8,865 citations

International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin).

1994 • 2,935 citations

Molecular biology of 5-HT receptors

1994 • 679 citations

New roles for G-protein (βγ-dimers in transmembrane signalling

1993 • 633 citations

Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits

1992 • 630 citations

5-HT3 receptors are membrane ion channels

1989 • 630 citations

Functional Correlates of Serotonin 5-HT₁Recognition Sites

1988 • 564 citations

Receptors for 5-Hydroxytryptamine: Current perspectives on classification and nomenclature

1994 • 304 citations

Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.

1993 • 281 citations

Serotonin stimulates DNA synthesis in fibroblasts acting through 5–HT1B receptors coupled to a Gi-protein

1988 • 277 citations

Effector Coupling Mechanisms of the Cloned 5-HT1A Receptor

1989 • 273 citations

Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.

1992 • 221 citations

Adenosine receptors.

1992 • 196 citations

The rat 5-hydroxytryptamine1B receptor is the species homologue of the human 5-hydroxytryptamine1D beta receptor.

1992 • 167 citations

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype.

1992 • 153 citations

Mechanisms of multifunctional signalling by G protein-linked receptors

1993 • 143 citations

Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems.

1994 • 130 citations

Centrally active 5-HT receptor agonists and antagonists

1992 • 112 citations

Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.

1993 • 110 citations

Agonist/antagonist interactions with cloned human 5-HT1A receptors: variations in intrinsic activity studied in transfected HeLa cells

1992 • 104 citations

Molecular cloning and characterisation of a human brain A1 adenosine receptor cDNA

1992 • 96 citations

Cell-specific signaling of the 5-HT1A receptor. Modulation by protein kinases C and A.

1991 • 89 citations

Transfected m2 muscarinic acetylcholine receptors couple to G alpha i2 and G alpha i3 in Chinese hamster ovary cells. Activation and desensitization of the phospholipase C signaling pathway.

1993 • 86 citations

A transduction pathway associated with receptors coupled to the inhibitory guanine nucleotide binding protein Gi that amplifies ATP-mediated arachidonic acid release.

1991 • 84 citations

Ability of delta-opioid receptors to interact with multiple G-proteins is independent of receptor density.

1994 • 81 citations

Complex information processing by the transmembrane signaling system involving G proteins

1994 • 71 citations

Influence of rolipram on the cyclic 3′,5′adenosine monophosphate response to histamine and adenosine in slices of guinea-pig cerebral cortex

1988 • 68 citations

Specific [3H]LY278584 binding to 5-HT3 recognition sites in rat cerebral cortex

1989 • 65 citations

Cell-specific coupling of the cloned human 5-HT1F receptor to multiple signal transduction pathways

1993 • 65 citations

Dual coupling of cloned human 5-hydroxytryptamine1D alpha and 5-hydroxytryptamine1D beta receptors stably expressed in murine fibroblasts: inhibition of adenylate cyclase and elevation of intracellular calcium concentrations via pertussis toxin-sensitive G protein(s).

1993 • 63 citations

Synergy between the inositol phosphate responses to transfected human adenosine A₁‐receptors and constitutive P₂‐purinoceptors in CHO‐K1 cells

1995 • 56 citations

Demonstration of both A1 and A2 adenosine receptors in DDT1 MF-2 smooth muscle cells.

1990 • 52 citations

Coupling of a transfected human brain A₁ adenosine receptor in CHO‐K1 cells to calcium mobilisation via a pertussis toxin‐sensitive mechanism

1994 • 44 citations

Adenosine A₁‐receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT₁ MF‐2 cells

1992 • 41 citations

Adenosine A₁‐receptor stimulated increases in intracellular calcium in the smooth muscle cell line, DDT₁MF‐2

1993 • 39 citations

Presence of vasoconstrictor 5HT₁‐like receptors revealed by precontraction of rabbit isolated mesenteric artery

1995 • 32 citations

Sumatriptan contracts large coronary arteries of beagle dogs through 5-HT1-like receptors

1992 • 22 citations

Inhibition by 5-HT of forskolin-induced cAMP Formation in the renal opossum Epithelial cell line OK: Mediation by a 5-HT1B like receptor and antagonism by methiothepin

1994 • 22 citations

The cloning and expression of an OK cell cDNA encoding a 5-hydroxytryptamine1B receptor.

1994 • 21 citations

5-Hydroxytryptamine 5-HT1B receptors inhibiting cyclic AMP accumulation in rat renal mesangial cells

1995 • 15 citations

Expression of beta2-adrenoceptors mediating cyclic AMP accumulation in astroglial and neuronal cell lines derived from the rat CNS

1990 • 12 citations