Lung preservation: The importance of endothelial and alveolar type II cell integrity

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Immunobiology: the immune system in health and disease

1995 • 3,893 citations

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

Nitric oxide: an endogenous modulator of leukocyte adhesion.

1991 • 3,079 citations

Peroxynitrite oxidation of sulfhydryls.

1991 • 2,479 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome

1993 • 1,811 citations

Pentoxifylline

1987 • 1,768 citations

Cytokines and endothelial cell biology

1990 • 1,275 citations

Arachidonic Acid Metabolites and the Interactions between Platelets and Blood-Vessel Walls

1979 • 1,158 citations

Cyclic guanosine monophosphate as a mediator of vasodilation.

1986 • 811 citations

Cell number and cell characteristics of the normal human lung.

1982 • 705 citations

Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine.

1977 • 692 citations

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

1991 • 691 citations

Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung.

1990 • 678 citations

Modulation of human platelet adenylate cyclase by prostacyclin (PGX)

1977 • 659 citations

Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome.

1991 • 647 citations

Cytokine Patterns in Patients After Major Vascular Surgery, Hemorrhagic Shock, and Severe Blunt Trauma Relation with Subsequent Adult Respiratory Distress Syndrome and Multiple Organ Failure

1993 • 628 citations

Nitric oxide modulates microvascular permeability

1992 • 564 citations

Surfactant and the Adult Respiratory Distress Syndrome

1993 • 554 citations

Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8

1993 • 529 citations

Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia.

1993 • 445 citations

Cytokines of the Lung

1990 • 443 citations

Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells.

1986 • 416 citations

Activation of human neutrophils with 1-O-hexadecyl/octadecyl-2-acetyl-sn-glycerol-3-phosphorylcholine (platelet activating factor).

1981 • 390 citations

Pharmacology of the Endothelium in Ischemia-Reperfusion and Circulatory Shock

1993 • 293 citations

Selectins: Novel Receptors that Mediate Leukocyte Adhesion During Inflammation

1991 • 264 citations

Cytokine-induced neutrophil-derived interleukin-8.

1992 • 260 citations

A strategy to increase the donor pool: Use of cadaver lungs for transplantation

1991 • 252 citations

Inhaled nitric oxide reduces human lung allograft dysfunction

1996 • 237 citations

Successful outcome of lung transplantation is not compromised by the use of marginal donor lungs

1995 • 234 citations

Inhaled Nitric Oxide

1993 • 220 citations

The surfactant system and lung phospholipid biochemistry.

1985 • 216 citations

Inhaled nitric oxide as a therapy for pulmonary hypertension after operations for congenital heart defects

1994 • 214 citations

Surfactant Abnormalities in Patients with Respiratory Failure after Multiple Trauma

1989 • 211 citations

Shear stress increases endothelial platelet-derived growth factor mRNA levels

1991 • 208 citations

Time course and mechanism of endothelial dysfunction in isolated ischemic- and hypoxic-perfused rat hearts

1990 • 204 citations

Hypoxia-induced increased permeability of endothelial monolayers occurs through lowering of cellular cAMP levels

1992 • 197 citations

Inhaled nitric oxide in the treatment of postoperative graft dysfunction after lung transplantation

1994 • 193 citations

Pattern of Injury and the Role of Neutrophils in Reperfusion Injury of Rat Lung

1995 • 192 citations

The nitric oxide/cyclic GMP pathway in organ transplantation: critical role in successful lung preservation.

1994 • 190 citations

Free Radical Chemistry of Nitric Oxide

1994 • 173 citations

Alveolar type II epithelial cells produce interleukin-6 in vitro and in vivo. Regulation by alveolar macrophage secretory products.

1994 • 173 citations

The Registry of the International Society for Heart and Lung Transplantation: twelfth official report--1995.

1995 • 172 citations

Improved airway healing after lung transplantation

1995 • 160 citations

Lung preservation: A review of current practice and future directions

1993 • 139 citations

Tumor necrosis factor alpha-induced pulmonary vascular endothelial injury

1989 • 139 citations

The role of dextran 40 and potassium in extended hypothermic lung preservation for transplantation

1992 • 129 citations

Pathophysiology of Pulmonary Edema Following Experimental Brain Death in the Chacma Baboon

1987 • 129 citations

Platelet-Activating Factor Raises Airway and Vascular Pressures and Induces Edema in Lungs Perfused with Platelet-Free Solution^1–3

1984 • 123 citations

Type II alveolar cell. Defender of the alveolus.

1977 • 122 citations

ARDS, Neutrophils, and Pentoxifylline

1988 • 120 citations

Evaluation of lung metabolism during successful twenty-four-hour canine lung preservation

1993 • 120 citations

Role of ICAM-1 in neutrophil-mediated lung vascular injury after occlusion and reperfusion

1991 • 106 citations

Leukotrienes and inflammation

1990 • 105 citations

O2 metabolites and neutrophil elastase synergistically cause edematous injury in isolated rat lungs

1986 • 104 citations

Polymorphonuclear leukocytes as a significant source of tumor necrosis factor-alpha in endotoxin-challenged lung tissue.

1993 • 104 citations

Antibody against leukocyte integrin (CD18) prevents reperfusion-induced lung vascular injury

1990 • 104 citations

New trends in lung preservation: a collective review.

1992 • 98 citations

Alterations in Pulmonary Surfactant Composition and Activity after Experimental Lung Transplantation

1993 • 97 citations

Compounds that increase cAMP prevent ischemia-reperfusion pulmonary capillary injury

1992 • 95 citations

Coronary vasoconstriction in the rat, isolated perfused heart induced by platelet‐activating factor is mediated by leukotriene C₄

1986 • 95 citations

THE EARLY RELEASE OF INTERLEUKIN-2, TUMOR NECROSIS FACTOR-α AND INTERFERON-γ AFTER ISCHEMIA REPERFUSION INJURY IN THE LUNG ALLOGRAFT

1994 • 93 citations

Cadaver lung donors: Effect of preharvest ventilation on graft function

1993 • 92 citations

When does the lung die? I. Histochemical evidence of pulmonary viability after "death".

1994 • 88 citations

Disparate effects of nitric oxide on lung ischemia-reperfusion injury

1995 • 88 citations

Characterization of exosurf (surfactant)-mediated suppression of stimulated human alveolar macrophage cytokine responses.

1994 • 83 citations

Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model.

1993 • 81 citations

Endothelin. Pathways of transmembrane signaling.

1990 • 78 citations

Leukocyte depletion results in excellent heart-lung function after 12 hours of storage

1990 • 72 citations

EFFECT OF RECOVERY FROM ISCHEMIC INJURY ON CLASS I AND CLASS II MHC ANTIGEN EXPRESSION

1990 • 72 citations

Neutrophils are not necessary for ischemia-reperfusion lung injury

1992 • 69 citations

Effect of recovery from ischemic injury on class I and class II MHC antigen expression.

1990 • 69 citations

THE EFFECT OF LOW-POTASSIUM-DEXTRAN VERSUS EURO-COLLINS SOLUTION FOR PRESERVATION OF ISOLATED TYPE II PNEUMOCYTES

1991 • 69 citations

Nitroprusside Ameliorates Lung Allograft Reperfusion Injury

1996 • 63 citations

Enhanced Preservation of Orthotopically Transplanted Rat Lungs by Nitroglycerin but Not Hydralazine

1995 • 61 citations

Hypovolemic shock promotes neutrophil sequestration in lungs by a xanthine oxidase-related mechanism

1991 • 60 citations

Activated Pulmonary Vascular Neutrophils as Early Mediators of Endotoxin-induced Lung Inflammation

1993 • 60 citations

Inhaled nitric oxide fails to confer the pulmonary protection provided by distal stimulation of the nitric oxide pathway at the level of cyclic guanosine monophosphate

1995 • 59 citations

A clinical trial of University of Wisconsin solution for pulmonary preservation

1993 • 59 citations

The Effects of Brain Death on Cardiopulmonary Hemodynamics and Pulmonary Blood Flow Characteristics

1995 • 58 citations

Leukocyte CD11b/18 Antigen-directed Monoclonal Antibody Improves Early Survival and Decreases Hypoxemia in Dogs Challenged with Tumor Necrosis Factor

1992 • 57 citations

Evaluation of surfactant treatment strategies after prolonged graft storage in lung transplantation.

1996 • 57 citations

Xanthine oxidase-derived oxygen radicals induce pulmonary edema via direct endothelial cell injury

1989 • 55 citations

Biology of Lung Preservation for Transplantation

1992 • 55 citations

Surfactant treatment before reperfusion improves the immediate function of lung transplants in rats.

1996 • 55 citations

THE DEVELOPMENT OF PULMONARY ULTRASTRUCTURAL LESIONS DURING HEMORRHAGIC SHOCK

1975 • 53 citations

Cytokine gene transcripts for tumor necrosis factor-alpha, interleukin-2, and interferon-gamma in human pulmonary allografts.

1995 • 52 citations

Safe pulmonary preservation for 12 hours with low-potassium-dextran solution

1993 • 52 citations

Lung Mast Cells Increase in Number and Degranulate during Pulmonary Artery Occlusion/Reperfusion Injury in Dogs

1993 • 52 citations

WHENCE THE LUNGS? A STUDY TO ASSESS SUITABILITY OF DONOR LUNGS FOR TRANSPLANTATION 1

1992 • 51 citations

The function of surfactant is impaired during the reimplantation response in rat lung transplants.

1994 • 50 citations

Fiberoptic bronchoscopy in brain-dead organ donors.

1994 • 49 citations

Nitroglycerin maintains graft vascular homeostasis and enhances preservation in an orthotopic rat lung transplant model

1995 • 49 citations

Cardiac and pulmonary replacement Inhaled nitric oxide improves lung allograft function after prolonged storage

1996 • 47 citations

Free radical—mediated vascular injury in lungs preserved at moderate hypothermia

1995 • 47 citations

Neutrophil-Endothelial Cell Interactions in the Lung

1993 • 46 citations

Administration of prostaglandin E1 after lung transplantation improves early graft function

1994 • 46 citations

Contribution of endothelin-1 to warm ischemia/reperfusion injury of the rat lung.

1995 • 45 citations

Effect of a free radical scavenger on cadaver lung transplantation

1993 • 44 citations

Pulmonary function after non—heart-beating lung donation in a survival model

1995 • 43 citations

Time limits of cadaver lung viability

1968 • 43 citations

Interleukin-6, a marker of preservation injury in clinical lung transplantation.

1992 • 43 citations

Pentoxifylline Reduces Injury to Isolated Lungs Perfused with Human Neutrophils

1991 • 42 citations

Pentoxifylline reduces lung allograft reperfusion injury

1994 • 42 citations

Exogenous surfactant therapy in thirty-eight hour lung graft preservation for transplantation

1994 • 39 citations

Pulmonary Artery Endothelial Dysfunction following Ischemia and Reperfusion of the Rabbit Lung

1993 • 39 citations

The bimodal expression of tumor necrosis factor-alpha in association with rat lung reimplantation and allograft rejection.

1993 • 37 citations

Improved lung function by urokinase infusion in canine lung transplantation using non-heart-beating donors

1995 • 36 citations

Nebulized synthetic surfactant in reperfusion injury after single lung transplantation

1995 • 34 citations

Synthesis of 1-acyl-2-[3H]acetyl-sn-glycero-3-phosphocholine, a structural analog of platelet activating factor, by vascular endothelial cells

1991 • 33 citations

Impairment of vascular endothelial function by high-potassium storage solutions

1993 • 33 citations

Effect of hypotension preceding death on the function of lungs from donors with nonbeating hearts.

1996 • 32 citations

Survival in lung reperfusion injury is improved by an antibody that binds and inhibits L- and E-selectin.

1994 • 32 citations

Surfactant analysis and replacement therapy: A future tool of the lung transplant surgeon?

1991 • 31 citations

Reduction of ischemia-reperfusion injury by pentoxifylline in the isolated rat lung. Paris-Sud University Lung Transplantation Group.

1994 • 31 citations

Neutrophil modulation results in improved pulmonary function after 12 and 24 hours of preservation

1995 • 31 citations

Interferon Production in Rat Type II Pneumocytes and Alveolar Macrophages

1989 • 29 citations

Effects of platelet-activating factor antagonist CV-3988 in preservation of heart and lung for transplantation

1991 • 27 citations

Neutrophil endopeptidase inhibitor improves pulmonary function during reperfusion after eighteen-hour preservation

1996 • 27 citations

Endothelium-dependent relaxation in pulmonary arteries after lung preservation and transplantation

1993 • 27 citations

Lung oxidant injury in a model of lung storage and extended reperfusion.

1994 • 24 citations

Lung preservation with low-potassium dextran flush in a primate bilateral transplant model

1993 • 23 citations

LONG-TERM LUNG PRESERVATION WITH THE PAF ANTAGONIST BN 52021

1991 • 20 citations

Expression of Interleukin-6 in Association with Rat Lung Reimplantation and Allograft Rejection

1993 • 19 citations

THE EFFECT OF PROTEASE INHIBITOR ON REPERFUSION INJURY AFTER UNILATERAL PULMONARY ISCHEMIA

1993 • 19 citations

Lung reperfusion injury is reduced by inhibiting a CD18-dependent mechanism.

1993 • 19 citations

Effect of ischemic injury on subsequent rat lung allograft rejection

1995 • 16 citations

University of Wisconsin solution for lung graft preservation: which components are important?

1994 • 15 citations

Pathophysiology of leukocyte-mediated tissue injury

1991 • 10 citations

Potential mechanism of vasomotor dysregulation after lung transplantation for primary pulmonary hypertension.

1995 • 9 citations

Enhanced isolated lung function after ischemia with antinintercellular adhesion molecule antibody

1996 • 8 citations

Expression of intercellular and vascular cell adhesion molecules and class II major histocompatibility antigens in human lungs: lack of influence by conditions of organ preservation.

1995 • 7 citations

Lung preservation threshold in a compromised septic lung injury model

1995 • 6 citations

ENHANCEMENT OF EXTENDED LUNG PRESERVATION WITH A VASOACTIVE INTESTINAL PEPTIDE-ENRICHED UNIVERSITY OF WISCONSIN SOLUTION

1995 • 5 citations

ENHANCEMENT OF EXTENDED LUNG PRESERVATION WITH A VASOACTIVE INTESTINAL PEPTIDE-ENRICHED UNIVERSITY OF WISCONSIN SOLUTION

1995 • 4 citations