Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

The Triad of Sleep Apnea, Hypertension, and Chronic Kidney Disease: A Spectrum of Common Pathology

2016 • 3,202 citations

EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN

1989 • 1,625 citations

Carbon Monoxide: a Putative Neural Messenger

1993 • 1,519 citations

Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction.

1991 • 1,134 citations

Release of endothelin from the porcine aorta. Inhibition by endothelium-derived nitric oxide.

1990 • 1,066 citations

Regulation of the Erythropoietin Gene: Evidence That the Oxygen Sensor Is a Heme Protein

1988 • 1,042 citations

Increased Plasma Endothelin-1 in Pulmonary Hypertension: Marker or Mediator of Disease?

1991 • 983 citations

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium.

1991 • 691 citations

Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium‐derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin

1988 • 400 citations

Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells.

1990 • 390 citations

Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia.

1991 • 321 citations

Sera and conditioned media contain different isoforms of platelet-derived growth factor (PDGF) which bind to different classes of PDGF receptor

1989 • 216 citations

Atrial natriuretic peptide, nitroglycerine, and nitroprusside reduce basal and stimulated endothelin production from cultured endothelial cells

1990 • 148 citations

Endothelin: A New Cardiovascular Regulatory Peptide

1990 • 133 citations

Endothelin-3 regulates endothelin-1 production in cultured human endothelial cells.

1991 • 78 citations

Effect of endothelium-derived relaxing factor inhibition on theumbilical-placental circulation in fetal lambs in utero

1992 • 76 citations

The platelet‐derived growth factor isomers, PDGF‐AA, PDGF‐AB and PDGF‐BB, induce contraction of vascular smooth muscle cells by different intracellular mechanisms

1990 • 61 citations

Endothelium-derived vasoactive factors and the renal vasculature

1991 • 54 citations

Reduced oxygen tension induces pulmonary endothelium to release a pulmonary smooth muscle cell mitogen(s).

1987 • 51 citations

Modulatory role of EDRF in hypoxic contraction of isolated porcine pulmonary arteries

1992 • 45 citations

Endothelin-like pulmonary vasoconstrictor peptide release by alpha-thrombin.

1989 • 34 citations

Deletions of specific regions of the simian sarcoma-associated virus genome are found in defective viruses and in the simian sarcoma virus

1982 • 17 citations