Identification of Phosphorylation Sites of Human 85-kDa Cytosolic Phospholipase A2 Expressed in Insect Cells and Present in Human Monocytes

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database

1994 • 6,412 citations

cPLA2 is phosphorylated and activated by MAP kinase

1993 • 1,858 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases

1991 • 1,327 citations

Method to Correlate Tandem Mass Spectra of Modified Peptides to Amino Acid Sequences in the Protein Database

1995 • 1,269 citations

Cell Biology: a Laboratory Handbook

1995 • 1,226 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.

1992 • 546 citations

Phosphorylation and activation of a high molecular weight form of phospholipase A2 by p42 microtubule-associated protein 2 kinase and protein kinase C.

1993 • 521 citations

A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7.

1990 • 447 citations

Mining Genomes: Correlating Tandem Mass Spectra of Modified and Unmodified Peptides to Sequences in Nucleotide Databases

1995 • 373 citations

Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.

1994 • 352 citations

Translocation of the 85-kDa Phospholipase A2 from Cytosol to the Nuclear Envelope in Rat Basophilic Leukemia Cells Stimulated with Calcium Ionophore or IgE/Antigen

1995 • 331 citations

Bacterial lipopolysaccharide stimulates protein tyrosine phosphorylation in macrophages.

1991 • 318 citations

Preparation and evaluation of packed capillary liquid chromatography columns with inner diameters from 20 to 50 micrometers

1989 • 293 citations

Properties and purification of an arachidonoyl-hydrolyzing phospholipase A2 from a macrophage cell line, RAW 264.7

1988 • 236 citations

Protein kinase C-dependent and -independent pathways of mitogen-activated protein kinase activation in macrophages by stimuli that activate phospholipase A2.

1994 • 229 citations

Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.

1988 • 203 citations

Thrombin-induced phosphorylation and activation of Ca(2+)-sensitive cytosolic phospholipase A2 in human platelets.

1993 • 191 citations

Regulation of phospholipase A2 activation by phosphorylation in mouse peritoneal macrophages.

1993 • 158 citations

Differential Activation of Cytosolic Phospholipase A2 (cPLA2) by Thrombin and Thrombin Receptor Agonist Peptide in Human Platelets. EVIDENCE FOR ACTIVATION OF cPLA2 INDEPENDENT OF THE MITOGEN-ACTIVATED PROTEIN KINASES ERK1/2

1995 • 126 citations

Substrate specificities and properties of human phospholipases A2 in a mixed vesicle model.

1992 • 118 citations

Suppression of monocyte 85-kDa phospholipase A2 by antisense and effects on endotoxin-induced prostaglandin biosynthesis

1994 • 116 citations

Macrophage colony stimulating factor activates phosphatidylcholine hydrolysis by cytoplasmic phospholipase A2.

1992 • 114 citations

Interleukin 1 alpha causes rapid activation of cytosolic phospholipase A2 by phosphorylation in rat mesangial cells.

1994 • 108 citations

Bacterial lipopolysaccharide primes human neutrophils for enhanced release of arachidonic acid and causes phosphorylation of an 85-kD cytosolic phospholipase A2.

1994 • 108 citations

Identification of phosphorylation sites in rat liver CTP: phosphocholine cytidylyltransferase.

1994 • 107 citations

Processive interfacial catalysis by mammalian 85-kilodalton phospholipase A2 enzymes on product-containing vesicles: Application to the determination of substrate preferences

1993 • 89 citations

Agonist-induced phosphorylation and desensitization of human m2 muscarinic cholinergic receptors in Sf9 insect cells.

1992 • 73 citations

Macrophage arachidonate-mobilizing phospholipase A2: Role of Ca2+ for membrane binding but not for catalytic activity

1992 • 64 citations

Analysis of oligodeoxynucleotides by negative-ion matrix-assisted laser desorption mass spectrometry

1993 • 62 citations

Regulation of arachidonate‐mobilizing phospholipase A₂ by phosphorylation via protein kinase C in macrophages

1992 • 62 citations

Kinetic analysis of a high molecular weight phospholipase A2 from rat kidney: divalent metal-dependent trapping of enzyme on product-containing vesicles

1992 • 58 citations

Regulation of cytosolic phospholipase A2 phosphorylation and eicosanoid production by colony-stimulating factor 1.

1994 • 54 citations

A Mitogen-Activated Protein Kinase-Independent Pathway Involved in the Phosphorylation and Activation of Cytosolic Phospholipase A2 in Human Neutrophils Stimulated with Tumor Necrosis Factor-α

1995 • 43 citations

The 85-kDa, Arachidonic Acid-Specific Phospholipase A2 Is Expressed as an Activated Phosphoprotein in Sf9 Cells

1993 • 39 citations

Coinfection of insect cells with recombinant baculovirus expressing pp60v-src results in the activation of a serine-specific protein kinase pp90rsk.

1990 • 35 citations

Arachidonic acid turnover in response to lipopolysaccharide and opsonized zymosan in human monocyte-derived macrophages

1986 • 32 citations

Phosphorylation and activation of the arachidonate‐mobilizing phospholipase A₂ in macrophages in response to bacteria

1993 • 29 citations

Active baculovirus recombinant p70s6k and p85s6k produced as a function of the infectious response.

1993 • 26 citations

Characterization by Electrospray Mass Spectrometry of Human Ca2+–sensitive Cytosolic Phospholipase A2 Produced in Baculovirus–infected Insect Cells

1994 • 25 citations

Human cytosolic phospholipase A2 expressed in insect cells is extensively phosphorylated on Ser-505

1995 • 24 citations