Kinetic analysis of a high molecular weight phospholipase A2 from rat kidney: divalent metal-dependent trapping of enzyme on product-containing vesicles

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Use of resonance energy transfer to monitor membrane fusion

1981 • 1,274 citations

Multiple, Distinct Forms of Bovine and Human Protein Kinase C Suggest Diversity in Cellular Signaling Pathways

1986 • 1,044 citations

Interfacial Catalysis: the Mechanism of Phospholipase A ₂

1990 • 693 citations

Fluorescence method for measuring the kinetics of fusion between biological membranes

1984 • 670 citations

Structure and Properties of a Human Non-pancreatic Phospholipase A2

1989 • 668 citations

Cloning and Recombinant Expression of Phospholipase A2 Present in Rheumatoid Arthritic Synovial Fluid

1989 • 542 citations

Structure and function of phospholiphase A2

1981 • 478 citations

[14] Measurement of cytosolic free Ca2+ with quin2

1989 • 466 citations

Phospholipase A2 and its zymogen from porcine pancreas. VI. Histidine at the active site of phospholipase A2

1974 • 465 citations

Molecular cloning and expression of human Ca(2+)-sensitive cytosolic phospholipase A2

1991 • 447 citations

A calcium-dependent mechanism for associating a soluble arachidonoyl-hydrolyzing phospholipase A2 with membrane in the macrophage cell line RAW 264.7.

1990 • 447 citations

Purification of a 110-kilodalton cytosolic phospholipase A2 from the human monocytic cell line U937.

1990 • 428 citations

The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells.

1991 • 413 citations

The substrate specificity of phospholipase A

1963 • 330 citations

The kinetics of interfacial catalysis by phospholipase A2 and regulation of interfacial activation: hopping versus scooting

1989 • 261 citations

X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor

1990 • 241 citations

Properties and purification of an arachidonoyl-hydrolyzing phospholipase A2 from a macrophage cell line, RAW 264.7

1988 • 236 citations

Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.

1988 • 203 citations

Structure of recombinant human rheumatoid arthritic synovial fluid phospholipase A2 at 2.2 Å resolution

1991 • 201 citations

Purification of a high-molecular-mass form of phospholipase A2 from rat kidney activated at physiological calcium concentrations

1990 • 174 citations

Interaction of phospholipase A2 and phospholipid bilayers

1982 • 142 citations

Origin of the latency phase during the action of phospholipase A2 on unmodified phosphatidylcholine vesicles

1982 • 134 citations

Kinetic properties of a high molecular mass arachidonoyl-hydrolyzing phospholipase A2 that exhibits lysophospholipase activity

1991 • 133 citations

Purification of a phospholipase A2 from human monocytic leukemic U937 cells. Calcium-dependent activation and membrane association.

1990 • 125 citations

Translocation of phospholipase A2 from cytosol to membranes in rat brain induced by calcium ions

1990 • 124 citations

Kinetics of interfacial catalysis by phospholipase A2 in intravesicle scooting mode, and heterofusion of anionic and zwitterionic vesicles

1986 • 119 citations

The role of Asp‐49 and other conserved amino acids in phospholipases A2 and their importance for enzymatic activity

1989 • 115 citations

Purification and characterization of human platelet phospholipase A₂ which preferentially hydrolyzes an arachidonoyl residue

1991 • 115 citations

Purification and characterization of rabbit platelet cytosolic phospholipase A2

1991 • 103 citations

Association of lysophosphatidylcholine with fatty acids in aqueous phase to form bilayers

1980 • 99 citations

Interfacial catalysis by phospholipase A2: substrate specificity in vesicles

1991 • 99 citations

Stimulation of Ca2+-activated human platelet phospholipase A2 by diacylglycerol

1987 • 98 citations

Extensive segregation of acidic phospholipids in membranes induced by protein kinase C and related proteins

1991 • 97 citations

Solubilization and properties of Ca2+-dependent human platelet phospholipase A2

1986 • 94 citations

Interfacial catalysis by phospholipase A2: dissociation constants for calcium, substrate, products, and competitive inhibitors

1991 • 92 citations

Binding of phospholipase A2 to zwitterionic bilayers is promoted by lateral segregation of anionic amphiphiles

1989 • 85 citations

A phospholipase A₂ hydrolyzing arachidonoyl‐phospholipids in mouse peritonea macrophages

1989 • 84 citations

[10] Phospholipase A2-catalyzed hydrolysis of vesicles: Uses of interfacial catalysis in the scooting mode

1991 • 75 citations

Formation of inverted lipid micelles in aqueous dispersions of mixed sn-3-galactosyldiacylglycerols induced by heat and ethylene glycol

1982 • 72 citations

Interfacial catalysis by phospholipase A2: monomeric enzyme is fully catalytically active at the bilayer interface

1991 • 72 citations

Characterization of phospholipase A2 in monocytic cell lines. Functional and biochemical aspects of membrane association

1991 • 46 citations

Affinity chromatography of phospholipase A2 from Naja naja naja (Indian cobra) venom

1985 • 46 citations

Purification and some properties of a phospholipase A2 from bovine platelets

1991 • 37 citations

Ca²⁺‐induced reversible translocation of phospholipase A₂ between the cytosol and the membrane fraction of rat liver macrophages

1991 • 33 citations

Calcium is sufficient but not necessary for activation of sheep platelet cytosolic phospholipase A₂

1991 • 19 citations

Factors contributing to the distribution of free fatty acids among phospholipid vesicles

1990 • 6 citations