Phosphorylation and activation of the arachidonate‐mobilizing phospholipase A₂ in macrophages in response to bacteria

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii

2007 • 11,720 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Human cyclooxygenase-2 cDNA.

1992 • 1,493 citations

Okadaic acid: a new probe for the study of cellular regulation

1990 • 1,396 citations

How is the level of free arachidonic acid controlled in mammalian cells?

1982 • 1,193 citations

Intracellular phospholipases A

1980 • 989 citations

The induction and suppression of prostaglandin H2 synthase (cyclooxygenase) in human monocytes.

1990 • 940 citations

Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.

1992 • 546 citations

The Ca2(+)-sensitive cytosolic phospholipase A2 is a 100-kDa protein in human monoblast U937 cells.

1991 • 413 citations

Regulation of fibroblast cyclooxygenase synthesis by interleukin-1.

1988 • 401 citations

Interleukin 1 activates phospholipase A2 in rabbit chondrocytes: a possible signal for IL 1 action.

1986 • 259 citations

Inflammatory factors stimulate expression of group II phospholipase A2 in rat cultured astrocytes. Two distinct pathways of the gene expression

1991 • 253 citations

Properties and purification of an arachidonoyl-hydrolyzing phospholipase A2 from a macrophage cell line, RAW 264.7

1988 • 236 citations

Identification and characterization of a hormonally regulated form of phospholipase A2 in rat renal mesangial cells.

1988 • 203 citations

Purification of a high-molecular-mass form of phospholipase A2 from rat kidney activated at physiological calcium concentrations

1990 • 174 citations

An 100‐kDa arachidonate‐mobilizing phospholipase A₂ in mouse spleen and the macrophage cell line J774

1991 • 136 citations

Kinetic properties of a high molecular mass arachidonoyl-hydrolyzing phospholipase A2 that exhibits lysophospholipase activity

1991 • 133 citations

Stimulation of de novo synthesis of prostaglandin G/H synthase in human endothelial cells by phorbol ester.

1988 • 132 citations

Epidermal growth factor enhances glomerular mesangial cell soluble phospholipase A2 activity.

1990 • 130 citations

Interleukin-1β, tumor necrosis factor and forskolin stimulate the synthesis and secretion of group II phospholipase A2 in rat mesangial cells

1991 • 106 citations

Analysis of leukotrienes, prostaglandins, and other oxygenated metabolites of arachidonic acid by high-performance liquid chromatography

1984 • 105 citations

The control of free arachidonic acid levels

1990 • 101 citations

Interleukin-1 alpha stimulates prostaglandin biosynthesis in serum-activated mesangial cells by induction of a non-pancreatic (type II) phospholipase A2

1991 • 96 citations

A phospholipase A₂ hydrolyzing arachidonoyl‐phospholipids in mouse peritonea macrophages

1989 • 84 citations

Evidence for a catalytic role of phospholipase A in phorbol diester- and zymosan-induced mobilization of arachidonic acid in mouse peritoneal macrophages

1986 • 82 citations

Phorbol ester, 1,2-diacylglycerol, and collagen induce inhibition of arachidonic acid incorporation into phospholipids in human platelets

1989 • 73 citations

Regulation of arachidonate‐mobilizing phospholipase A₂ by phosphorylation via protein kinase C in macrophages

1992 • 62 citations

Regulation of prostaglandin synthesis by protein kinase C in mouse peritoneal macrophages

1989 • 55 citations

The diacylglycerols dioctanoylglycerol and oleoylacetylglycerol enhance prostaglandin synthesis by inhibition of the lysophosphatide acyltransferase

1987 • 46 citations

A role for protein kinase C-mediated phosphorylation in the mobilization of arachidonic acid in mouse macrophages

1989 • 46 citations

Okadaic acid and dinophysistoxin-1, non-TPA-type tumor promoters, stimulate prostaglandin E2 production in rat peritoneal macrophages

1989 • 29 citations

Receptor-Mediated Signal Transduction in Mononuclear Phagocytes

2015 • 25 citations

Protein‐kinase‐C‐independent activation of arachidonate release and prostaglandin E₂ formation in macrophages interacting with certain bacteria

1991 • 19 citations

Differential Effect of Diacylglycerols and Phorbol Ester on Arachidonic Acid Metabolism in Bone Marrow-Derived Macrophages

1990 • 10 citations