Generation of cytotoxic immune responses during the progression of a rat glioma

Immunity to Methylcholanthrene-Induced Sarcomas

1957 • 1,241 citations

Antigenic properties of methylcholanthrene-induced tumors in mice of the strain of origin.

1953 • 686 citations

Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma.

1987 • 478 citations

Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes.

1991 • 402 citations

Tumor Eradication by Adoptive Transfer of Cytototic T Lymphocytes

1992 • 281 citations

Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas.

1986 • 259 citations

Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2.

1991 • 217 citations

The Murine Antitumor Immune Response and Its Therapeutic Manipulation

1984 • 164 citations

The role of tumor-specific Lyt-1+2- T cells in eradicating tumor cells in vivo. I. Lyt-1+2- T cells do not necessarily require recruitment of host's cytotoxic T cell precursors for implementation of in vivo immunity.

1984 • 156 citations

Elimination of syngeneic sarcomas in rats by a subset of T lymphocytes.

1980 • 141 citations

Tumor-specific transplantation antigens: G. H. A. Clowes memorial lecture.

1968 • 132 citations

Specific adoptive therapy of established leukemia with syngeneic lymphocytes sequentially immunized in vivo and in vitro and nonspecifically expanded by culture with Interleukin 2.

1981 • 130 citations

Generation from tumor-bearing mice of lymphocytes with in vivo therapeutic efficacy.

1987 • 129 citations

Clonal analysis of cytotoxic T‐lymphocyte response to autologous human metastatic melanoma

1985 • 107 citations

In vitro sensitization and expansion with viable tumor cells and interleukin 2 in the generation of specific therapeutic effector cells.

1986 • 89 citations

Lymphocytes generated by in vivo priming and in vitro sensitization demonstrate therapeutic efficacy against a murine tumor that lacks apparent immunogenicity.

1989 • 89 citations

Adoptive immunotherapy of established syngeneic solid tumors: role of T lymphoid subpopulations.

1984 • 80 citations

Establishment of interleukin 2 dependent cytotoxic T lymphocyte cell line specific for autologous brain tumor and its intracranial administration for therapy of the tumor

1987 • 69 citations

Specific adoptive immunotherapy with tumor-specific cytotoxic T-lymphocyte clone for murine malignant gliomas.

1984 • 64 citations

T cell-mediated immunity to oncornavirus-induced tumors. II. Ability of different T cell sets to prevent tumor growth in vivo.

1980 • 63 citations

Role of different T cells sets in the rejection of syngeneic chemically induced tumors.

1979 • 60 citations

Antitumor activity against established intracerebral gliomas exhibited by cytotoxic T lymphocytes, but not by lymphokine-activated killer cells

1992 • 52 citations

Successful Treatment of a Malignant Rat Glioma with Cytotoxic T Lymphocytes

1992 • 48 citations

Clonal analysis of cytotoxic T lymphocytes (CTL) against autologous melanoma

1986 • 46 citations

Human autologous tumor-specific T cells in malignant melanoma

1991 • 37 citations

Role of Different T Cell Sets in the Rejection of Syngeneic Chemically Induced Tumors

1979 • 35 citations

Generation of Cytotoxic Immune Responses against a Rat Glioma by in Vivo Priming and Secondary in Vitro Stimulation with Tumor Cells

1992 • 34 citations

Cytotoxic T lymphocyte recognition of gp70 on Friend virus-induced erythroleukemia cell clones.

1980 • 31 citations

Recruitment and activation of tumor-specific immune T cells in situ. CD8+ cells predominate the secondary response in sponge matrices and exert both delayed-type hypersensitivity-like and cytotoxic T lymphocyte activity.

1989 • 28 citations

Specific cytotoxic activity of T lymphocyte clones derived from a patient with gliosarcoma

1988 • 26 citations

Induction of human glioma-specific cytotoxic T-lymphocyte lines by autologous tumor stimulation and interleukin 2

1986 • 25 citations

Melanoma cell lysis by human CTL clones: Differential involvement of T3, T8 and HLA antigens

1987 • 14 citations

Intralesional Immunotherapy of Brain Tumors With Combined Corynebacterium parvum and Recombinant Interleukin-2 in Mice

1990 • 8 citations