Melanoma cell lysis by human CTL clones: Differential involvement of T3, T8 and HLA antigens

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores.

1985 • 742 citations

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.

1986 • 698 citations

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line.

1984 • 504 citations

Antigen recognition by human T lymphocytes is linked to surface expression of the T3 molecular complex

1982 • 494 citations

Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor

1983 • 464 citations

T-cell-mediated cytotoxicity against autologous malignant melanoma: analysis with interleukin 2-dependent T-cell cultures.

1984 • 237 citations

Clonal analysis of cytotoxic T cell response against human melanoma.

1983 • 138 citations

Cloned human cytotoxic T lymphocyte (CTL) lines reactive with autologous melanoma cells. I. In vitro generation, isolation, and analysis to phenotype and specificity.

1984 • 133 citations

The role of T cell differentiation markers in antigen-specific and lectin-dependent cellular cytotoxicity mediated by T8+ and T4+ human cytotoxic T cell clones directed at class I and class II MHC antigens.

1982 • 121 citations

Identification of a clonally restricted 90 kD heterodimer on two human cloned natural killer cell lines. Its role in cytotoxic effector function.

1983 • 115 citations

Clonal analysis of cytotoxic T‐lymphocyte response to autologous human metastatic melanoma

1985 • 107 citations

Distinct forms of both alpha and beta subunits are present in the human Ia molecular pool.

1981 • 92 citations

Clonal heterogeneity in the requirement for T3, T4, and T8 molecules in human cytolytic T lymphocyte function.

1984 • 76 citations

CLONAL ANALYSIS OF T LYMPHOCYTES ISOLATED FROM OVARIAN CARCINOMA ASCITIC FLUID. PHENOTYPIC AND FUNCTIONAL CHARACTERIZATION OF T-CELL CLONES CAPABLE OF LYSING AUTOLOGOUS CARCINOMA CELLS

1985 • 74 citations

Tumour-reactive lymphocytes stimulated in mixed lymphocyte and tumour culture

1983 • 63 citations

Assignment of human natural killer (NK)‐like cells to the T cell lineage. Single allospecific T cell clones lyse specific or NK‐sensitive target cells via distinct recognition structures

1984 • 60 citations

A cloned human T cell line cytotoxic for autologous and allogeneic B lymphoma cells.

1984 • 57 citations

Heterogeneity of clones from a human metastatic melanoma detected by autologous cytotoxic T lymphocyte clones.

1986 • 57 citations

Identification of a 140‐kDa activation antigen as a target structure for a series of human cloned natural killer cell lines

1984 • 47 citations

Clonal analysis of cytotoxic T lymphocytes (CTL) against autologous melanoma

1986 • 46 citations

Lysis of autologous human melanoma cells by in vitro allosensitized peripheral blood lymphocytes

1982 • 34 citations

Expression of the NKTa clonotype in a series of human natural killer clones with identical cytotoxic specificity.

1986 • 30 citations

The role of T8 in the cytotoxic activity of cloned cytotoxic T lymphocyte lines specific for class II and class I major histocompatibility complex antigens.

1985 • 29 citations

Human normal CTL clones: Generation and properties

1983 • 22 citations

Proliferative and cytotoxic responses of human peripheral blood lymphocytes to autologous malignant effusions

1986 • 14 citations

Separation, phenotyping and cloning of tumor infiltrating lymphocytes from human solid tumors

1986 • 1 citations