Review: Advances in Intraperitoneal (Intracavitary) Administration of Synthetic Polymers for Immunotherapy and Chemotherapy

The blood supply of neoplasms in the liver.

1954 • 1,280 citations

Intraperitoneal Cisplatin with Systemic Thiosulfate Protection

1982 • 494 citations

Contemporary Topics in Immunobiology

1977 • 410 citations

Soluble synthetic polymers as potential drug carriers

1984 • 308 citations

Phase I and pharmacological studies of 5-fluorouracil administered intraperitoneally.

1980 • 249 citations

Immune Modulation Agents and their Mechanisms

1985 • 246 citations

Lipid Angiogenic Factor From Omentum

1984 • 233 citations

Phospholipid metabolism by phagocytic cells. Phospholipases A2 associated with rabbit polymorphonuclear leukocyte granules

1974 • 222 citations

Phase I and pharmacological studies of adriamycin administered intraperitoneally to patients with ovarian cancer.

1982 • 218 citations

Portal levels and hepatic clearance of 5-fluorouracil after intraperitoneal administration in humans.

1981 • 211 citations

Cellular and Molecular Mechanisms of Action of Bacterial Endotoxins

1979 • 198 citations

Nonlinear pharmacokinetic models for 5-fluorouracil in man: Intravenous and intraperitoneal routes

1980 • 181 citations

Site–Specific (Targeted) Drug Delivery in Cancer Therapy

1983 • 166 citations

Immune modulation and control of neoplasia by adjuvant therapy

1978 • 152 citations

Improved regional selectivity of hepatic arterial bcnu with degradable microspheres

1982 • 144 citations

Control of neoplasia by modulation of the immune system

1977 • 130 citations

Activation of macrophages

1985 • 124 citations

Biological Effects of Polynucleotides

1971 • 120 citations

Intraperitoneal contrast infusion for assessment of intraperitoneal fluid dynamics

1979 • 117 citations

High volume intraperitoneal chemotherapy (?Belly bath?) for ovarian cancer

1978 • 107 citations

High-volume intraperitoneal chemotherapy with methotrexate in patients with cancer.

1981 • 100 citations

Specific inhibition of antibody production. I. Protein-over loading paralysis.

1962 • 99 citations

Transport of Model Compounds across the Peritoneal Membrane in the Rat

1978 • 97 citations

Immunopharmacology of glucan: a broad spectrum enhancer of host defense mechanisms

1983 • 95 citations

Combination intraperitoneal chemotherapy with cisplatin, cytarabine, and doxorubicin for refractory ovarian carcinoma and other malignancies principally confined to the peritoneal cavity.

1984 • 94 citations

Novel Approaches to Cancer Chemotherapy

1984 • 93 citations

A Totally Implanted Injection Port System for Blood Sampling and Chemotherapy Administration

1984 • 89 citations

Inhibition of human ovarian cancer colony formation by adriamycin and its major metabolites.

1980 • 88 citations

Controlled Blocking of Hepatic Artery Flow with Enzymatically Degradable Microspheres Combined with Oncolytic Drugs

1979 • 86 citations

Pharmacology of Intraperitoneal Chemotherapy

1983 • 81 citations

Long-duration intracavitary infusion of methotrexate with systemic leucovorin protection in patients with malignant effusions.

1981 • 76 citations

Intraperitoneal cytosine arabinoside therapy in ovarian carcinoma.

1984 • 70 citations

Kinetics of sodium thiosulfate, a cisplatin neutralizer

1984 • 63 citations

The use of intraperitoneal chemotherapy in the treatment of ovarian cancer.

1984 • 59 citations

INTRACAVITARY ADRIAMYCIN NITROGEN MUSTARD AND TETRACYCLINE IN THE CONTROL OF MALIGNANT EFFUSIONS: A RANDOMIZED STUDY

1980 • 58 citations

Adjuvant liver perfusion in colorectal cancer: initial results of a clinical trial.

1977 • 55 citations

Intraperitoneal spread of malignancies and its effect on the bowel

1981 • 49 citations

The Use of Peritoneal Dialysis for Delivery of Chemotherapy to Intraperitoneal Malignancies

1980 • 46 citations

Peritoneal electrolyte absorption: analysis of portal, systemic venous, and lymphatic transport.

1968 • 45 citations

Interaction of mesothelium to intraperitoneal stimulation. I. Aggregation of peritoneal cells.

1983 • 44 citations

Constant intraperitoneal 5-fluorouracil infusion through a totally implanted system

1984 • 42 citations

Activation of the alternative pathway of complement: efficient fluid‐phase amplification by blockade of the regulatory complement protein β1H through sulfated polyanions

1981 • 40 citations

The Growth-Regulating Activity of Polyanions: A Theoretical Discussion of Their Place in the Intercellular Environment and their role in Cell Physiology

1969 • 36 citations

Immunomodulatory effect of various molecular-weight maleic anhydride-divinyl ethers and other agents in vivo.

1980 • 35 citations

Antiviral Activity and Side Effects of Polyriboinosinic-Cytidylic Acid Complexes as Affected by Molecular Size

1972 • 34 citations

Drug Targeting in Cancer Therapy

1984 • 29 citations

Intraperitoneal infusion of doxorubicin in the treatment of gynecologic carcinomas

1981 • 29 citations

Effect of pyran copolymer on activation of murine macrophages: evidence for incomplete activation by use of functional markers.

1983 • 26 citations

Hydrogen ion dynamics and cancer: An appraisal

1982 • 25 citations

Translocation of particles from lung lobes or the peritoneal cavity to regional lymph nodes in beagle dogs

1983 • 25 citations

Enhancement, by Two Carboxylic Acid Interferon Inducers, of Resistance Stimulated in Mice by Foot-and-Mouth Disease Vaccine

1973 • 24 citations

Hepatic artery ligation and portal vein infusion for liver metastases from colon cancer.

1984 • 24 citations

Polyinosinic-Polycytidylic Acid Toxicity

1971 • 24 citations

Some Biologically Active Copolymers of Maleic Anhydride^a

1985 • 23 citations

A comparative study of histamine secretion from rat peritoneal and pleural mast cells

1982 • 22 citations

Fibronectin levels during intraperitoneal inflammation

1983 • 21 citations

Inhibition and enhancement of Friend leukemia virus by pyran copolymer.

1975 • 21 citations

Systemic toxicity of polyinosinic acid: Polycytidylic acid in rodents and dogs

1971 • 20 citations

Clinical Science Review: The Routinization of Intraperitoneal (Intracavitary) Chemotherapy and Immunotherapy

1986 • 20 citations

Platelet Blockade of Particle Absorption from the Peritoneal Surface of the Diaphragm

1981 • 17 citations

Drug targeting: Magnetically responsive albumin microspheres—A review of the system to date

1981 • 16 citations

Reduced incidence of rat colon cancer metastases by perioperative immunostimulation with maleic anhydride-divinyl ether-2 (MVE-2)

1985 • 11 citations

Mechanisms of the adjuvant effect of hemoglobin in experimental peritonitis. IV. The adjuvant effect of hemoglobin in granulocytopenic rats.

1981 • 11 citations

Studies on topical chemotherapy of tumor-contaminated surgical wounds

1963 • 11 citations

Intra-Arterial and Intracavitary Cancer Chemotherapy

2011 • 11 citations

Intraperitoneal Infusion of Non-Absorbable Steroids in the Treatment of Ascites and Sterile Peritonitis

1980 • 11 citations

The Modulation of immunity

1985 • 10 citations

Effect of Erythrocyte Debris on Reticuloendothelial Function and Susceptibility to Experimental Peritonitis

1981 • 10 citations

Mechanism of increased antitumor immunity by a synthetic polymer

1980 • 10 citations

Polyanion, Immunoprotein and Proteinase Inhibitor in Ischemic Glomerular Change

1981 • 9 citations

Polyanions and Glucose as Osmotic Agents in Simulated Peritoneal Dialysis

1983 • 9 citations

In vivo modulation of myelopoiesis and immune functions by maleic anhydride divinyl ether copolymer (MVE-2) in tumor-free and MBL-2 tumor-bearing mice treated with cyclophosphamide.

1985 • 8 citations

Immunological and Tumor Responses to Various Immunotherapeutic Agents

1981 • 8 citations

Current Status of Human Cancer Immunotherapy

1981 • 6 citations

Accumulation of T cells and local antippd antibody production in lymphokine‐mediated chronic peritoneal inflammation in the guinea pig

1980 • 5 citations

Tissue distribution of adriamycin administered intraperitoneally vs. intravenously, with special emphasis on the pancreas.

1982 • 5 citations

Macrophage Activation and Antitumor Activity of Cyclohexyl‐1,3‐dioxepin and 4‐Methyl‐2‐pentonyl Maleic Anhydride Copolymers^a

1985 • 4 citations

A Phase I Trial of Intracavitary Doxorubicin (Adriamycin) Alternating with Cisplatin

1984 • 4 citations

Determination of the biological response modifier MVE-2 (AD-022) in biological fluids by high-performance liquid chromatography

1983 • 3 citations

Phase I Trials and Pharmacokinetic Studies of Intraperitoneal Cisplatin, Melphalan, Methotrexate, and Cytarabine

1984 • 3 citations

Intracavity 5-fluorouracil for control of malignant effusions.

1968 • 2 citations