Sphingosine 1-phosphate regulates peritoneal B-cell trafficking for subsequent intestinal IgA production

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

2000 • 3,323 citations

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

2004 • 2,462 citations

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 • 1,655 citations

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

2002 • 1,478 citations

B Cell Development Pathways

2001 • 1,185 citations

CD69 acts downstream of interferon-α/β to inhibit S1P1 and lymphocyte egress from lymphoid organs

2006 • 1,092 citations

Marginal Zone and B1 B Cells Unite in the Early Response against T-Independent Blood-Borne Particulate Antigens

2001 • 955 citations

CHEMOKINES, SPHINGOSINE-1-PHOSPHATE, AND CELL MIGRATION IN SECONDARY LYMPHOID ORGANS

2004 • 840 citations

NALT- versus PEYER'S-patch-mediated mucosal immunity

2004 • 684 citations

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

2005 • 681 citations

Progenitors for Ly-1 B cells are distinct from progenitors for other B cells.

1985 • 599 citations

B-1a and B-1b Cells Exhibit Distinct Developmental Requirements and Have Unique Functional Roles in Innate and Adaptive Immunity to S. pneumoniae

2005 • 590 citations

FTY720, a Novel Immunosuppressant, Induces Sequestration of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing in Rats. I. FTY720 Selectively Decreases the Number of Circulating Mature Lymphocytes by Acceleration of Lymphocyte Homing

1998 • 586 citations

The immunosuppressant FTY720 down‐regulates sphingosine 1‐phosphate G protein‐coupled receptors

2004 • 532 citations

CXCL13 Is Required for B1 Cell Homing, Natural Antibody Production, and Body Cavity Immunity

2002 • 521 citations

Intestinal IgA synthesis: regulation of front-line body defences

2003 • 489 citations

FTY720: Sphingosine 1-Phosphate Receptor-1 in the Control of Lymphocyte Egress and Endothelial Barrier Function

2004 • 462 citations

Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues

2005 • 458 citations

Structural and functional characteristics of S1P receptors

2004 • 450 citations

The origin and antigen-dependent distribution of IgA-containing cells in the intestine.

1978 • 422 citations

Identification of a B-1 B cell–specified progenitor

2006 • 410 citations

Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone

2004 • 403 citations

B1b Lymphocytes Confer T Cell-Independent Long-Lasting Immunity

2004 • 399 citations

Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions

2000 • 393 citations

Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors

1993 • 392 citations

B1 cells: similarities and differences with other B cell subsets

2001 • 387 citations

The Role of CXCR4 in Maintaining Peripheral B Cell Compartments and Humoral Immunity

2004 • 371 citations

Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity

1989 • 351 citations

CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells

2003 • 328 citations

Homeostasis of Peripheral B Cells in the Absence of B Cell Influx from the Bone Marrow

2001 • 313 citations

FTY720, a new class of immunomodulator, inhibits lymphocyte egress from secondary lymphoid tissues and thymus by agonistic activity at sphingosine 1-phosphate receptors

2005 • 292 citations

Sphingosine 1‐phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis

2000 • 276 citations

Activation‐regulated expression and chemotactic function of sphingosine 1‐phosphate receptors in mouse splenic T cells

2002 • 229 citations

A marvel of mucosal T cells and secretory antibodies for the creation of first lines of defense.

2005 • 198 citations

Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism

2006 • 198 citations

Molecular cloning and characterization of a lipid phosphohydrolase that degrades sphingosine-1- phosphate and induces cell death

2000 • 195 citations

The sphingosine 1-phosphate receptor agonist FTY720 supports CXCR4-dependent migration and bone marrow homing of human CD34+ progenitor cells

2004 • 145 citations

An embryonic source of Ly1 but not conventional B cells

1991 • 145 citations

Immunosuppressant FTY720 inhibits thymocyte emigration

2000 • 135 citations

CC Chemokine Receptor 7–dependent and –independent Pathways for Lymphocyte Homing

2001 • 126 citations

Regulation of immunity by lysosphingolipids and their G protein–coupled receptors

2004 • 124 citations

A new immunosuppressant, FTY720, induces bcl‐2‐associated apoptotic cell death in human lymphocytes

1996 • 121 citations

The B/macrophage cell: an elusive link between CD5+ B lymphocytes and macrophages

1996 • 118 citations

FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L‐positive T cells in Peyer’s patches by FTY720‐induced lymphocyte homing

1998 • 114 citations

The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell–expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches

2005 • 110 citations

Deficiency of IL-5 receptor alpha-chain selectively influences the development of the common mucosal immune system independent IgA-producing B-1 cell in mucosa-associated tissues.

1999 • 99 citations

Generation, expansion, migration and activation of mouse B1 cells

2000 • 96 citations

IL-15 and IL-15 Receptor Selectively Regulate Differentiation of Common Mucosal Immune System-Independent B-1 Cells for IgA Responses

2000 • 82 citations

Deficiency of IL-5 Receptor α-Chain Selectively Influences the Development of the Common Mucosal Immune System Independent IgA-Producing B-1 Cell in Mucosa-Associated Tissues

1999 • 79 citations

Omental milky spots in the local immune response in the peritoneal cavity of rats

1996 • 76 citations

FTY720-Enhanced T Cell Homing Is Dependent on CCR2, CCR5, CCR7, and CXCR4: Evidence for Distinct Chemokine Compartments

2004 • 69 citations

Intranasal Immunization with Heat-Inactivated Streptococcus pneumoniae Protects Mice against Systemic Pneumococcal Infection

1999 • 65 citations

Mucosa-Associated Lymphoid Tissues in the Aerodigestive Tract: Their Shared and Divergent Traits and Their Importance to the Orchestration of the Mucosal Immune System

2005 • 63 citations

Sendai Virus Fusion Protein-Mediates Simultaneous Induction of MHC Class I/II-Dependent Mucosal and Systemic Immune Responses Via the Nasopharyngeal-Associated Lymphoreticular Tissue Immune System

2001 • 61 citations

Sphingosine 1-phosphate receptor agonist FTY720-phosphate causes marginal zone B cell displacement

2005 • 59 citations

Distinct and overlapping roles of CXCR5 and CCR7 in B-1 cell homing and early immunity against bacterial pathogens

2004 • 56 citations

Interleukin-10 modulates the sensitivity of peritoneal B lymphocytes to chemokines with opposite effects on stromal cell–derived factor-1 and B-lymphocyte chemoattractant

2002 • 54 citations

FTY720 suppresses humoral immunity by inhibiting germinal center reaction

2004 • 45 citations

Intestinal epithelial barrier and mucosal immunity

2005 • 44 citations

Metastatic pattern of CC531 colon carcinoma cells in the abdominal cavity: an experimental model of peritoneal carcinomatosis in rats

2001 • 42 citations

Lack of antigen-specific immune responses in anti-IL-7 receptor α chain antibody-treated Peyer's patch-null mice following intestinal immunization with microencapsulated antigen

2002 • 38 citations

CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells

2003 • 28 citations

Immunosuppressant FTY720 inhibits thymocyte emigration

2000 • 12 citations

IL-5-induced IgA synthesis by LPS-stimulated mouse B cells is prevented by protein kinase C inhibitors.

1992 • 6 citations

Omental milky spots in the local immune response in the peritoneal cavity of rats

1996 • 1 citations