Endogenous Myc maintains the tumor microenvironment

Modes of resistance to anti-angiogenic therapy

2008 • 2,783 citations

Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations

2002 • 2,711 citations

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

2000 • 2,700 citations

Induction of angiogenesis during the transition from hyperplasia to neoplasia

1989 • 1,912 citations

Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

2005 • 1,578 citations

Reflecting on 25 years with MYC

2008 • 1,447 citations

Heritable formation of pancreatic β-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

1985 • 1,292 citations

Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis

2006 • 864 citations

Modelling Myc inhibition as a cancer therapy

2008 • 779 citations

Suppression of Myc-Induced Apoptosis in β Cells Exposes Multiple Oncogenic Properties of Myc and Triggers Carcinogenic Progression

2002 • 624 citations

SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation

2005 • 526 citations

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors

2007 • 481 citations

Reversible Activation of c-Myc in Skin

1999 • 468 citations

Effects of fixation on RNA extraction and amplification from laser capture microdissected tissue

1999 • 325 citations

Role of Bv8 in neutrophil-dependent angiogenesis in a transgenic model of cancer progression

2008 • 299 citations

The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1β

2006 • 184 citations

Design and properties of a Myc derivative that efficiently homodimerizes

1998 • 182 citations

The enhancer domain of the human cytomegalovirus major immediate-early promoter determines cell type-specific expression in transgenic mice

1996 • 169 citations

Vascular endothelial growth factor as a marker of tumor endothelium.

1998 • 168 citations

Omomyc, a potential Myc dominant negative, enhances Myc-induced apoptosis.

2002 • 150 citations

The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice

1991 • 136 citations

Expression Profiling of Ductal Carcinoma in Situ by Laser Capture Microdissection and High-Density Oligonucleotide Arrays

2001 • 131 citations

Matrix metalloproteinase inhibitors for cancer therapy: the current situation and future prospects

2003 • 100 citations

SV40 small T antigen and PP2A phosphatase in cell transformation

2008 • 94 citations

Omomyc expression in skin prevents Myc-induced papillomatosis

2004 • 72 citations

Can tumor angiogenesis be inhibited without resistance?

2005 • 69 citations

Molecular dissection of multi-stage tumorigenesis in transgenic mice.

1994 • 55 citations

Unusual cell specific expression of a major human cytomegalovirus immediate early gene promoter-lacZ hybrid gene in transgenic mouse embryos

1991 • 38 citations

Simian virus 40 large T overcomes p300 repression of c-Myc

2008 • 10 citations