Characterization and Implications of Estrogenic Down-Regulation of Human Catechol-O-Methyltransferase Gene Transcription

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture.

1976 • 820 citations

Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators

1997 • 731 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

1995 • 692 citations

Molecular Mechanisms of Estrogen Carcinogenesis

1996 • 659 citations

Catecholamine metabolism: basic aspects and clinical significance.

1985 • 589 citations

Catechol-O-methyl transferase: pharmacological aspects and physiological role.

1975 • 547 citations

Transdermal oestrogen for treatment of severe postnatal depression

1996 • 546 citations

Estrogen Receptor in a Human Cell Line (MCF-7) from Breast Carcinoma

1973 • 415 citations

The neurochemistry of Parkinson's disease: effect of L-dopa therapy.

1975 • 386 citations

Estrone and Estradiol Levels in the Ovarian Venous Blood from Rats During the Estrous Cycle and Pregnancy*

1971 • 384 citations

Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP patients requiring levodopa

1996 • 353 citations

Genomic organization of the human catechol O‐methyltransferase gene and its expression from two distinct promoters

1994 • 332 citations

Estrogen-responsive element of the human pS2 gene is an imperfectly palindromic sequence.

1989 • 330 citations

A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically

1992 • 290 citations

An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer.

1997 • 286 citations

Human liver catechol-O-methyltransferase pharmacogenetics

1990 • 243 citations

Estradiol and testosterone in specific regions of the human female brain in different endocrine states

1995 • 202 citations

Gender differences in Parkinson's disease.

1998 • 173 citations

[34] Catechol O-methyltransferase

1981 • 119 citations

Involvement of CCAAT/enhancer-binding protein and nuclear factor-kappa B binding sites in interleukin-6 promoter inhibition by estrogens.

1996 • 112 citations

Quercetin Increases the Severity of Estradiol-Induced Tumorigenesis in Hamster Kidney

1994 • 108 citations

S-adenosylmethionine treatment of depression: a controlled clinical trial

1988 • 100 citations

Catechol-O-Methyl Transferase Activity in the Human Term Placenta

1988 • 84 citations

Erythrocyte catechol‐O‐methyltransferase activity in a Swedish population

1981 • 61 citations

PLASMA ADRENALINE, NORADRENALINE AND DOPAMINE IN PREGNANCY HYPERTENSION

1981 • 53 citations

G/A₁₉₄₇ polymorphism in catechol‐O‐methyltransferase (COMT) gene in Parkinson's disease

1997 • 49 citations

Erythrocyte COMT‐activity in patients with affective disorders

1980 • 46 citations

Involvement of CCAAT/enhancer-binding protein and nuclear factor-kappa B binding sites in interleukin-6 promoter inhibition by estrogens

1996 • 40 citations

Induction of nuclear catechol-O-methyltransferase by estrogens in hamster kidney: implications for estrogen-induced renal cancer

1998 • 37 citations

VARIATION IN ACTIVITY OF MONOAMINE METABOLIZING ENZYMES IN RAT LIVER DURING PREGNANCY

1975 • 36 citations

Variations in catechol O-methyltransferase activity in rodent tissues: possible role in estrogen carcinogenicity

1989 • 32 citations

Detection of estrogen receptor (ER) in the rat brain using rat anti-ER monoclonal IgG with the unlabeled antibody method

1991 • 21 citations

Activity of catechol-O-methyltransferase in brain regions and adrenal gland during the oestrus cycle

1978 • 21 citations

Characterization of the Rat Catechol-O-Methyltransferase Gene Proximal Promoter: Identification of a Nuclear Protein–DNA Interaction That Contributes to the Tissue-Specific Regulation

1996 • 17 citations

Catechol-O-methyltransferase: Factors Relating to the Carcinogenic Potential of Catecholestrogens

1994 • 13 citations

DECREASED PHENYLETHANOLAMINE‐N‐METHYLTRANSFERASE AND CATECHOL‐O‐METHYLTRANSFERASE ACTIVITY IN RABBIT ADRENAL GLANDS DURING PREGNANCY

1976 • 8 citations