The Requirement of both Intracellular Reactive Oxygen Species and Intracellular Calcium Elevation for the Induction of Heparin-Binding EGF-like Growth Factor in Vascular Endothelial Cells and Smooth Muscle Cells

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1.

1991 • 3,819 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

Biology of disease: free radicals and tissue injury.

1982 • 3,078 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

1983 • 1,808 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells.

1992 • 1,524 citations

A Heparin-Binding Growth Factor Secreted by Macrophage-Like Cells That Is Related to EGF

1991 • 1,135 citations

Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation.

1992 • 949 citations

Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme.

1992 • 920 citations

Rapid and preferential activation of the c-jun gene during the mammalian UV response.

1991 • 685 citations

Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-α

1989 • 660 citations

Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF.

1993 • 581 citations

UV-induced DNA damage is an intermediate step in UV-induced expression of human immunodeficiency virus type 1, collagenase, c-fos, and metallothionein.

1989 • 549 citations

A role for oxygen radicals as second messengers

1991 • 494 citations

Regulation of interleukin 8 gene expression by oxidant stress.

1993 • 395 citations

Heparin-binding EGF-like growth factor stimulation of smooth muscle cell migration: dependence on interactions with cell surface heparan sulfate

1993 • 365 citations

Structure of heparin-binding EGF-like growth factor. Multiple forms, primary structure, and glycosylation of the mature protein.

1992 • 346 citations

Functional angiotensin II receptors in cultured vascular smooth muscle cells.

1982 • 346 citations

Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury.

1993 • 334 citations

Transcriptional activation of early‐response genes by hydrogen peroxide in a mouse osteoblastic cell line

1991 • 298 citations

Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobulin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase.

1993 • 275 citations

DNA damage-induced gene expression: Signal transduction and relation to growth factor signaling

1992 • 187 citations

Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques.

1995 • 171 citations

Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like growth factor gene in vascular endothelial cells.

1992 • 144 citations

Second messenger role for NO widens to nervous and immunesystem

1989 • 135 citations

Heparin-binding epidermal growth factor-like growth factor expression in cultured fetal human vascular smooth muscle cells. Induction of mRNA levels and secretion of active mitogen.

1993 • 134 citations

Induction of heparin-binding epidermal growth factor-like growth factor mRNA by phorbol ester and angiotensin II in rat aortic smooth muscle cells.

1992 • 103 citations

Structural organization and chromosomal assignment of the gene encoding the human heparin-binding epidermal growth factor-like growth factor/diphtheria toxin receptor

1993 • 65 citations

Production of hydrogen peroxide by murine epidermal keratinocytes following treatment with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.

1990 • 64 citations

Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells.

1993 • 62 citations

The effects of various growth factors on endothelial cell survival in vitro

1989 • 10 citations