HSPG modulation of BMP signaling in fibrodysplasia ossificans progressiva cells

Developmental regulation of the growth plate

2003 • 2,694 citations

Functions of Cell Surface Heparan Sulfate Proteoglycans

1999 • 2,660 citations

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

2006 • 1,145 citations

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

1999 • 919 citations

BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation

2001 • 432 citations

Id helix—loop—helix proteins in cell growth and differentiation

1998 • 413 citations

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

2001 • 398 citations

Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless

2001 • 370 citations

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

2001 • 369 citations

Glypicans: proteoglycans with a surprise

2001 • 360 citations

Overexpression of an Osteogenic Morphogen in Fibrodysplasia Ossificans Progressiva

1996 • 360 citations

Glypicans: proteoglycans with a surprise

2001 • 337 citations

Multiple functions of BMPs in chondrogenesis

2004 • 296 citations

Ext1-Dependent Heparan Sulfate Regulates the Range of Ihh Signaling during Endochondral Ossification

2004 • 273 citations

Sulfated Polysaccharides Enhance the Biological Activities of Bone Morphogenetic Proteins

2003 • 262 citations

Mice deficient in Ext2 lack heparan sulfate and develop exostoses

2005 • 246 citations

Dimethylmethylene blue-based spectrophotometry of glycosaminoglycans in untreated urine: a rapid screening procedure for mucopolysaccharidoses.

1989 • 218 citations

Opposing Activities of Dally-like Glypican at High and Low Levels of Wingless Morphogen Activity

2004 • 213 citations

The syndecans, tuners of transmembrane signaling

1999 • 211 citations

Heparan Sulfate Proteoglycans Retain Noggin at the Cell Surface

2002 • 209 citations

Hereditary multiple exostosis and chondrosarcoma: linkage to chromosome II and loss of heterozygosity for EXT-linked markers on chromosomes II and 8.

1995 • 194 citations

Domain-specific Modification of Heparan Sulfate by Qsulf1 Modulates the Binding of the Bone Morphogenetic Protein Antagonist Noggin

2004 • 190 citations

Bone morphogenetic protein 2 transiently enhances expression of a gene, Id (inhibitor of differentiation), encoding a helix-loop-helix molecule in osteoblast-like cells.

1993 • 167 citations

Developmental roles of the glypicans

2001 • 162 citations

Id helix-loop-helix proteins in cell growth and differentiation

1998 • 149 citations

The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins

2001 • 147 citations

Fibrodysplasia ossificans progressiva

2001 • 128 citations

ALK2 Functions as a BMP Type I Receptor and Induces Indian Hedgehog in Chondrocytes During Skeletal Development

2003 • 122 citations

Acute Lymphocytic Infiltration in an Extremely Early Lesion of Fibrodysplasia Ossificans Progressiva

1998 • 118 citations

Heparan sulfate is required for bone morphogenetic protein-7 signaling

2003 • 117 citations

Bone morphogenetic protein in early fibromatous lesions of fibrodysplasia ossificans progressiva

1997 • 117 citations

The Phenotype of Fibrodysplasia Ossificans Progressiva

2005 • 115 citations

Dysregulation of the BMP-p38 MAPK Signaling Pathway in Cells From Patients With Fibrodysplasia Ossificans Progressiva (FOP)

2006 • 112 citations

BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog

2001 • 110 citations

The E2A and tal-1 helix-loop-helix proteins associate in vivo and are modulated by Id proteins during interleukin 6-induced myeloid differentiation.

1994 • 110 citations

Fibrodysplasia Ossificans Progressiva (FOP), a Disorder of Ectopic Osteogenesis, Misregulates Cell Surface Expression and Trafficking of BMPRIA

2005 • 106 citations

Neuronal Expression of Regulatory Helix-Loop-Helix Factor Id2 Gene in Mouse

1993 • 105 citations

Identification of Glypican as a Dual Modulator of the Biological Activity of Fibroblast Growth Factors

1997 • 105 citations

Regulating morphogen gradients in the Drosophila wing

2002 • 97 citations

Inhibitory helix‐loop‐helix transcription factors Id1/Id3 promote bone formation in vivo

2004 • 66 citations

Regulation of Cytokine Signaling by B Cell Antigen Receptor and Cd40-Controlled Expression of Heparan Sulfate Proteoglycans

2000 • 50 citations

Genotype/Phenotype Correlations of Males Affected by Simpson-Golabi-Behmel Syndrome with GPC3 Gene Mutations: Patient Report and Review of the Literature

2003 • 45 citations

Similarities and Differences between the Effects of Heparin and Glypican-1 on the Bioactivity of Acidic Fibroblast Growth Factor and the Keratinocyte Growth Factor

1999 • 44 citations

Cell Surface Heparan Sulfate Participates in CXCL1-Induced Signaling

2003 • 43 citations

Functional characterization and genetic mapping of alk8

2001 • 42 citations

Lymphoid-specific Expression of the Id3 Gene in Hematopoietic Cells

1998 • 39 citations

Proteoglycans Make the Grade-ient

2004 • 9 citations