Diacylglycerol kinase ζ regulates phosphatidylinositol 4-phosphate 5-kinase Iα by a novel mechanism

The Role of Phosphoinositide 3-Kinase Lipid Products in Cell Function

1999 • 1,007 citations

Regulation of protein kinase C

1997 • 919 citations

Phosphatidylinositol 4-Phosphate 5-Kinase α Is a Downstream Effector of the Small G Protein ARF6 in Membrane Ruffle Formation

1999 • 800 citations

Phosphoinositide Regulation of the Actin Cytoskeleton

2003 • 644 citations

PIP2 and PIP3

2000 • 538 citations

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

1997 • 435 citations

Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1

2002 • 421 citations

Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid

1994 • 410 citations

Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase.

1992 • 368 citations

Phosphoinositide Signaling Pathways in Nuclei Are Associated with Nuclear Speckles Containing Pre-mRNA Processing Factors

1998 • 328 citations

Diacylglycerols and phosphatidates: which molecular species are intracellular messengers?

1998 • 289 citations

Mammalian Diacylglycerol Kinases, a Family of Lipid Kinases with Signaling Functions

1999 • 284 citations

Type I Phosphatidylinositol-4-phosphate 5-Kinases

1998 • 280 citations

The synthesis and cellular roles of phosphatidylinositol 4,5-bisphosphate

1998 • 267 citations

Subcellular targeting by membrane lipids

2001 • 259 citations

Protein kinase C regulates the nuclear localization of diacylglycerol kinase-ζ

1998 • 256 citations

Properties and functions of diacylglycerol kinases

2000 • 245 citations

Type I Phosphatidylinositol-4-phosphate 5-Kinases Are Distinct Members of This Novel Lipid Kinase Family

1996 • 219 citations

Enhanced T cell responses due to diacylglycerol kinase ζ deficiency

2003 • 208 citations

Phosphoinositide kinase, diacylglycerol kinase, and phospholipase C activities associated to the cytoskeleton: effect of epidermal growth factor.

1991 • 202 citations

Diacylglycerol and Phosphatidate Generated by Phospholipases C and D, Respectively, Have Distinct Fatty Acid Compositions and Functions

1997 • 200 citations

Cloning of cDNAs Encoding Two Isoforms of 68-kDa Type I Phosphatidylinositol4-phosphate 5-Kinase

1996 • 200 citations

Interaction of pp60c-src, phospholipase C, inositol-lipid, and diacyglycerol kinases with the cytoskeletons of thrombin-stimulated platelets

1991 • 193 citations

Massive Actin Polymerization Induced by Phosphatidylinositol-4-phosphate 5-Kinase in Vivo

1997 • 174 citations

Molecular Cloning and Characterization of a Novel Human Diacylglycerol Kinase ζ

1996 • 167 citations

The α Isoform of Protein Kinase C Is Involved in Signaling the Response of Desmosomes to Wounding in Cultured Epithelial Cells

2000 • 163 citations

Characterization of a Rac1- and RhoGDI-Associated Lipid Kinase Signaling Complex

1998 • 147 citations

Sites of Ca2+ wave initiation move with caveolae to the trailing edge of migrating cells

2002 • 127 citations

Interaction of the Type Ialpha PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4,5-bisphosphate in the regulation of PLD2 activity

2000 • 122 citations

Diacylglycerol Kinases: Emerging Downstream Regulators in Cell Signaling Systems

2002 • 119 citations

Dynamics of phosphatidylinositol 4,5-bisphosphate in actin-rich structures

2000 • 119 citations

Signaling Complexes: Junctions on the Intracellular Information Super Highway

2002 • 116 citations

Diacylglycerol Kinase ζ Regulates Ras Activation by a Novel Mechanism

2001 • 110 citations

The mechanism involved in the regulation of phospholipase Cγ1 activity in cell migration

2002 • 109 citations

Coupled Inositide Phosphorylation and Phospholipase D Activation Initiates Clathrin-coat Assembly on Lysosomes

1999 • 108 citations

InsP3-induced Ca2+ excitability of the endoplasmic reticulum.

1995 • 104 citations

Cloning and expression of a cytoskeleton-associated diacylglycerol kinase that is dominantly expressed in cerebellum.

1994 • 99 citations

Association of diacylglycerol kinase ζ with protein kinase C α

2003 • 96 citations

Diacylglycerol kinase-θ is localized in the speckle domains of the nucleus

2003 • 92 citations

Src-mediated activation of alpha-diacylglycerol kinase is required for hepatocyte growth factor-induced cell motility

2000 • 91 citations

Diacylglycerol Kinase θ Binds to and Is Negatively Regulated by Active RhoA

1999 • 89 citations

G-protein-coupled Receptor Activation Induces the Membrane Translocation and Activation of Phosphatidylinositol-4-phosphate 5-Kinase Iα by a Rac- and Rho-dependent Pathway

2001 • 83 citations

Diacylglycerol kinase

1997 • 81 citations

Progress in protrusion: the tell-tale scar

1999 • 69 citations

Aggregation-dependent, integrin-mediated increases in cytoskeletally associated PtdInsP2 (4,5) levels in human platelets are controlled by translocation of PtdIns 4-P 5-kinase C to the cytoskeleton.

1996 • 63 citations

Diacylglycerol kinases in signal transduction

1999 • 49 citations

E2F3—A Novel Repressor of the ARF/p53 Pathway

2004 • 29 citations

Intracellular signalling: Is PIP2 a messenger too?

2000 • 26 citations