Amelioration of established murine collagen-induced arthritis with anti-IL-1 treatment

Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis.

1991 • 1,630 citations

Interleukin-1 receptor antagonist activity of a human interleukin-1 inhibitor

1990 • 1,143 citations

INHIBITORY EFFECT OF TNF$alpha; ANTIBODIES ON SYNOVIAL CELL INTERLEUKIN-1 PRODUCTION IN RHEUMATOID ARTHRITIS

1989 • 1,137 citations

Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis.

1992 • 1,002 citations

Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage

1986 • 742 citations

Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint.

1986 • 496 citations

Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice.

1992 • 363 citations

Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody.

1991 • 295 citations

Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.

1992 • 234 citations

Cytokines in autoimmunity

1996 • 231 citations

Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-alpha.

1991 • 204 citations

Immunity to cartilage proteoglycans in balb/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan

1987 • 171 citations

In vivo administration with IL-1 accelerates the development of collagen-induced arthritis in mice.

1988 • 158 citations

Pro- and anti-inflammatory roles of interleukin-1 in recurrence of bacterial cell wall-induced arthritis in rats

1991 • 151 citations

Effects of murine recombinant interleukin 1 on synovial joints in mice: measurement of patellar cartilage metabolism and joint inflammation.

1990 • 138 citations

Acceleration of onset of collagen-induced arthritis by intra-articular injection of tumour necrosis factor or transforming growth factor-beta

1992 • 103 citations

Protection against cartilage proteoglycan synthesis inhibition by antiinterleukin 1 antibodies in experimental arthritis.

1992 • 94 citations

Antigen-induced and zymosan-induced arthritis in mice: studies on in vivo cartilage proteoglycan synthesis and chondrocyte death.

1981 • 92 citations

Cytokines in autoimmunity

1992 • 89 citations

Exacerbation of arthritis by IL-1 in rat joints previously injured by peptidoglycan-polysaccharide.

1988 • 84 citations

T-cell vaccination

1988 • 83 citations

The role of cytokines and their inhibitors in arthritis

1992 • 80 citations

In vivo effects of interleukin‐1 on articular cartilage. Prolongation of proteoglycan metabolic disturbances in old mice

1991 • 75 citations

The mouse patella assay

1982 • 59 citations

Cationic immune complex arthritis in mice--a new model. Synergistic effect of complement and interleukin-1.

1992 • 53 citations

Bacterial lipopolysaccharide potentiates type II collagen‐induced arthritis in mice

1992 • 50 citations

Interleukin-1 potentiates the development of collagen-induced arthritis in mice

1989 • 49 citations

Antigen handling in antigen-induced arthritis in mice: an autoradiographic and immunofluorescence study using whole joint sections.

1982 • 46 citations

Flare-up of experimental arthritis in mice with murine recombinant IL-1

1992 • 32 citations

INTERLEUKINS AND ARTHRITIS

1993 • 28 citations

Influence of the severity and duration of murine antigen‐induced arthritis on cartilage proteoglycan synthesis and chondrocyte death

1985 • 26 citations

Experimental synovitis induced by collagen-specific T cell lines

1989 • 25 citations

Impact of NSAIDS on murine antigen induced arthritis. I. Investigation of antiinflammatory and chondroprotective effects.

1989 • 10 citations