Messenger RNAs of β‐amyloid precursor protein and prion protein are regulated by nerve growth factor in PC12 cells

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Nerve growth factor.

1968 • 2,025 citations

Amyloid β Protein Gene: cDNA, mRNA Distribution, and Genetic Linkage Near the Alzheimer Locus

1987 • 1,589 citations

A cellular gene encodes scrapie PrP 27-30 protein

1985 • 1,494 citations

Characterization and Chromosomal Localization of a cDNA Encoding Brain Amyloid of Alzheimer's Disease

1987 • 1,316 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Scrapie prions aggregate to form amyloid-like birefringent rods

1983 • 1,048 citations

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

1986 • 829 citations

PC12 Pheochromocytoma Cultures in Neurobiological Research

1982 • 728 citations

NGF-Mediated increase of choline acetyltransferase (ChAT) in the neonatal rat forebrain: Evidence for a physiological role of NGF in the brain?

1983 • 725 citations

Characterization and isolation of proteolytically modified nerve growth factor

1976 • 677 citations

Separation and properties of cellular and scrapie prion proteins.

1986 • 619 citations

Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

1985 • 490 citations

Scrapie prion proteins are synthesized in neurons.

1986 • 422 citations

Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons

1986 • 377 citations

Scrapie infectivity, fibrils and low molecular weight protein

1983 • 345 citations

The major polypeptide of scrapie-associated fibrils (SAF) has the same size, charge distribution and N-terminal protein sequence as predicted for the normal brain protein (PrP).

1986 • 322 citations

Localization of Amyloid β Protein Messenger RNA in Brains from Patients with Alzheimer's Disease

1987 • 297 citations

Identification of prion amyloid filaments in scrapie-infected brain

1985 • 293 citations

Nerve growth factor (NGF) stimulation of cholinergic telencephalic neurons in aggregating cell cultures

1982 • 291 citations

Antibodies to a scrapie prion protein

1984 • 260 citations

Neuronal localization of amyloid beta protein precursor mRNA in normal human brain and in Alzheimer's disease.

1987 • 222 citations

Scrapie-associated fibrils in Creutzfeldt–Jakob disease

1983 • 199 citations

Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent.

1986 • 176 citations

Nerve growth factor enhances expression of neuron-glia cell adhesion molecule in PC12 cells.

1986 • 139 citations

Selective enzyme induction in a nerve growth factor-responsive pheochromocytoma cell line (PC 12)

1978 • 122 citations

Induction of neurofilament triplet proteins in PC12 cells by nerve growth factor

1982 • 82 citations

Nerve growth factor activates Thy-1 and neurofilament gene transcription in rat PC12 cells

1986 • 76 citations

Serum and thyroid hormones T3 and T4 regulate nerve growth factor mRNA levels in mouse L cells

1985 • 53 citations

Neuropeptide Y (NPY) in pc12 phaeochromocytoma cultures: Responses to dexamethasone and nerve growth factor

1984 • 45 citations

Cooperative regulation of neurotensin content in PC12 pheochromocytoma cell cultures: effects of nerve growth factor, dexamethasone, and activators of adenylate cyclase

1986 • 41 citations

Characterization of major peptides in Creutzfeldt-Jakob disease and scrapie.

1986 • 40 citations

Pheochromocytoma PC12 cells influence the differentiation of co‐cultured skeletal myotubes

1986 • 3 citations