Identification of prion amyloid filaments in scrapie-infected brain

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Novel Proteinaceous Infectious Particles Cause Scrapie

1982 • 4,972 citations

Amyloid Deposits and Amyloidosis

1980 • 1,787 citations

Identification of a Protein That Purifies with the Scrapie Prion

1982 • 1,260 citations

Scrapie prions aggregate to form amyloid-like birefringent rods

1983 • 1,048 citations

A protease-resistant protein is a structural component of the Scrapie prion

1983 • 919 citations

Experimental Transmission of a Kuru-like Syndrome to Chimpanzees

1966 • 828 citations

Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples.

1981 • 815 citations

Alzheimer's Disease: Senile Dementia and Related Disorders

1979 • 801 citations

Creutzfeldt-Jakob Disease (Spongiform Encephalopathy): Transmission to the Chimpanzee

1968 • 778 citations

Conjugation of antibodies with fluorochromes: Modifications to the standard methods

1976 • 757 citations

Transfer of proteins from gels to diazobenzyloxymethyl-paper and detection with antisera: a method for studying antibody specificity and antigen structure.

1979 • 722 citations

Does the Agent of Scrapie Replicate without Nucleic Acid ?

1967 • 671 citations

ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.

1964 • 646 citations

CREUTZFELDT-JAKOB DISEASE VIRUS ISOLATIONS FROM THE GERSTMANN-STRÄUSSLER SYNDROME

1981 • 534 citations

Amyloid Deposits and Amyloidosis

1980 • 506 citations

ENCEPHALOPATHY IN MICE PRODUCED BY INOCULATION WITH SCRAPIE BRAIN MATERIAL

1961 • 505 citations

Purification and structural studies of a major scrapie prion protein

1984 • 497 citations

Abnormal fibrils from scrapie-infected brain

1981 • 473 citations

Further purification and characterization of scrapie prions

1982 • 464 citations

The exceptionally small size of the scrapie agent

1966 • 403 citations

Scrapie infectivity, fibrils and low molecular weight protein

1983 • 345 citations

Measurement of the scrapie agent using an incubation time interval assay

1982 • 339 citations

Pathology of Kuru.

1959 • 284 citations

Antibodies to a scrapie prion protein

1984 • 260 citations

Scrapie PrP 27-30 is a sialoglycoprotein

1985 • 231 citations

Infection-Specific Particle from the Unconventional Slow Virus Diseases

1984 • 214 citations

Molecular properties, partial purification, and assay by incubation period measurements of the hamster scrapie agent

1980 • 214 citations

Some Speculations about Prions, Amyloid, and Alzheimer's Disease

1984 • 212 citations

Senile plaques and cerebral amyloidosis in aged dogs. A histochemical and ultrastructural study.

1970 • 205 citations

Creutzfeldt–Jakob Disease Prion Proteins in Human Brains

1985 • 197 citations

A rapid procedure for preparing fluorescein-labeled specific antibodies from whole antiserum: its use in analyzing cytoskeletal architecture.

1983 • 189 citations

Scrapie in Mice: Ultrastructural Observations in the Cerebral Cortex

1968 • 185 citations

Comparison of Scrapie and Transmissible Mink Encephalopathy in Hamsters. II. Clinical Signs, Pathology, and Pathogenesis

1975 • 159 citations

Use of polylysine for adsorption of nuclei acids and enzymes to electron microscope specimen films.

1977 • 153 citations

CEREBRAL AMYLOIDOSIS IN SCRAPIE IN THE MOUSE: EFFECT OF AGENT STRAIN AND MOUSE GENOTYPE

1976 • 152 citations

Viroids and prions.

1982 • 145 citations

Autoantibodies Against Axonal Neurofilaments in Patients with Kuru and Creutzfeldt-Jakob Disease

1980 • 139 citations

Evidence for induction of localized amyloid deposits and neuritic plaques by an infectious agent

1981 • 123 citations

Infectious Etiology of Neuritic (Senile) Plaques in Mice

1975 • 113 citations

Reappraisal of the fine structure of Alzheimer's neurofibrillary tangles

1981 • 109 citations

EXPERIMENTAL SPONGIFORM ENCEPHALOPATHY (CREUTZFELDT-JAKOB DISEASE) IN CHIMPANZEES

1971 • 104 citations

Electron microscopic observations on the cerebellar cortex in Kuru

1969 • 91 citations

Spiroplasma-like inclusions in Creutzfeldt-Jakob disease.

1979 • 85 citations

Amyloid and senile plaques and cerebral blood vessels

1982 • 82 citations

Electron microscopic structure of the “inclusion bodies” in Pick's disease

1968 • 80 citations

Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants.

1985 • 77 citations

Slow, latent and temperate virus infections

1968 • 70 citations

Aggregations of 35-Nanometer Particles Associated with Neuronal Cytopathic Changes in Natural Scrapie

1971 • 68 citations

VIRUS-LIKE PARTICLES AND NUCLEOPROTEIN-TYPE FILAMENTS IN BRAIN TISSUE FROM TWO PATIENTS WITH CREUTZFELDT-JAKOB DISEASE

1970 • 68 citations

An electron-microscopic study of scrapie in the rat: Further observations on “inclusion bodies” and virus-like particles

1972 • 57 citations

Experimental scrapie in mice: Ultrastructural observations

1978 • 52 citations

An electron microscopic study of natural scrapie sheep brain: Further observations on virus-like particles and paramyxovirus-like tubules

1974 • 44 citations

Immunohistochemical demonstration of glial fibrillary acidic protein in scrapie

1983 • 42 citations

Ruthenium red and lanthanum nitrate a possible tracer and negative stain for scrapie ?particles??

1974 • 34 citations

Characterization of Antineurofilament Autoantibodies in Creutzfeldt-Jakob Disease

1984 • 29 citations

Post-embedding immunoperoxidase staining of glial fibrillary acidic protein for light and electron microscopy

1981 • 22 citations