Bridging the cleft at GABA synapses in the brain

Sequence and functional expression of the GABAA receptor shows a ligand-gated receptor super-family

1987 • 1,621 citations

A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system

1989 • 1,283 citations

Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex

1989 • 977 citations

The metabotropic glutamate receptor (mGluRlα) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction

1993 • 905 citations

A family of metabotropic glutamate receptors

1992 • 873 citations

The variance of sodium current fluctuations at the node of Ranvier

1980 • 772 citations

Fast events in single‐channel currents activated by acetylcholine and its analogues at the frog muscle end‐plate.

1985 • 768 citations

The Coupling of Neurotransmitter Receptors to Ion Channels in the Brain

1988 • 732 citations

Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites

1994 • 731 citations

Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

Local and diffuse synaptic actions of GABA in the hippocampus

1993 • 709 citations

Iontophoretic studies of neurones in the mammalian cerebral cortex

1963 • 659 citations

Electrophysiology of GABAA and GABAB receptor subtypes

1988 • 645 citations

A physiological role for GABAB receptors in the central nervous system

1988 • 643 citations

Nonuniform Probability of Glutamate Release at a Hippocampal Synapse

1993 • 641 citations

Neuropeptides in perspective: The last ten years

1991 • 620 citations

GABAB autoreceptors regulate the induction of LTP

1991 • 613 citations

GABA_B Receptor Pharmacology

1993 • 591 citations

Quantal analysis of synaptic potentials in neurons of the central nervous system.

1990 • 578 citations

Functional properties of recombinant rat GABAA receptors depend upon subunit composition

1990 • 557 citations

GABA receptor mechanisms in the central nervous system

1991 • 555 citations

Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: a patch‐clamp study.

1990 • 545 citations

Pharmacological evidence for two kinds of GABA receptors on rat hippocampal pyramidal cells studied in vitro

1982 • 527 citations

Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents

1991 • 480 citations

Glutamate receptor desensitization and its role in synaptic transmission

1989 • 459 citations

Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons

1993 • 446 citations

Quaternary Structure of the Native GABA_A Receptor Determined by Electron Microscopic Image Analysis

1994 • 423 citations

Synaptic excitation produces a long-lasting rebound potentiation of inhibitory synaptic signals in cerebellar Purkinje cells

1992 • 423 citations

A High Degree of Spatial Selectivity in the Axonal and Dendritic Domains of Physiologically Identified Local‐circuit Neurons in the Dentate Gyms of the Rat Hippocampus

1993 • 418 citations

GABAA receptor needs two homologous domains of the & beta;-subunit for activation by GABA but not by pentobarbital

1993 • 417 citations

Shunting of excitatory input to dentate gyrus granule cells by a depolarizing GABAA receptor-mediated postsynaptic conductance

1992 • 392 citations

Hippocampal pyramidal cells excite inhibitory neurons through a single release site

1993 • 388 citations

Benzodiazepine/GABA Receptors and Chloride Channels: Structural and Functional Properties.

1987 • 368 citations

The Role of GABA _B Receptor Activation in Absence Seizures of Lethargic ( lh / lh ) Mice

1992 • 355 citations

Presynaptic inhibition in the hippocampus

1993 • 354 citations

Distribution and kinetics of GABAB binding sites in rat central nervous system: A quantitative autoradiographic study

1990 • 347 citations

Multivesicular release from excitatory synapses of cultured hippocampal neurons

1994 • 333 citations

The components of synaptic potentials evoked in cat spinal motoneurones by impulses in single group Ia afferents.

1981 • 315 citations

Physiological evidence for two distinct GABAA responses in rat hippocampus

1993 • 304 citations

Dendritic attenuation of synaptic potentials and currents: the role of passive membrane properties

1994 • 287 citations

Quantal analysis and synaptic anatomy — integrating two views of hippocampal plasticity

1993 • 280 citations

Subdivisions in the Multiple GABAergic Innervation of Granule Cells in the Dentate Gyrus of the Rat Hippocampus

1993 • 275 citations

Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures

1992 • 270 citations

Neurobiology of alcohol abuse

1992 • 270 citations

Modulation of decay kinetics and frequency of GABAA receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons

1992 • 268 citations

Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapse

1993 • 264 citations

Opioid inhibition of GABA release from presynaptic terminals of rat hippocampal interneurons

1992 • 261 citations

Benzodiazepine/GABA receptors and chloride channels : structural and functional properties

1986 • 260 citations

Post‐synaptic potentiation: interaction between quanta of acetylcholine at the skeletal neuromuscular synapse.

1975 • 259 citations

How quickly can GABAA receptors open?

1994 • 249 citations

Characterization of synaptically elicited GABAB responses using patch‐clamp recordings in rat hippocampal slices.

1993 • 241 citations

Quantitative, three‐dimensional analysis of granule cell dendrites in the rat dentate gyrus

1990 • 235 citations

Noise analysis of miniature IPSCs in adult rat brain slices: properties and modulation of synaptic GABAA receptor channels

1994 • 222 citations

Synaptic inputs to GABAA and GABAB receptors originate from discrete afferent neurons

1992 • 220 citations

Benzodiazepine and beta‐carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture.

1994 • 214 citations

Perpetual inhibitory activity in mammalian brain slices generated by spontaneous GABA release

1991 • 206 citations

GABA-Activated Chloride Channels in Secretory Nerve Endings

1993 • 201 citations

Regional distribution and extracellular levels of amino acids in rat central nervous system

1986 • 200 citations

Effect of geometrical irregularities on propagation delay in axonal trees

1991 • 193 citations

Characteristics of miniature inhibitory postsynaptic currents in CA1 pyramidal neurones of rat hippocampus.

1990 • 185 citations

Intrinsic Quantal Variability Due to Stochastic Properties of Receptor-Transmitter Interactions

1992 • 181 citations

Immunogold demonstration of GABA in synaptic terminals of intracellularly recorded, horseradish peroxidase-filled basket cells and clutch cells in the cat's visual cortex

1986 • 181 citations

High Probability Opening of NMDA Receptor Channels by L-Glutamate

1992 • 166 citations

Norepinephrine decreases synaptic inhibition in the rat hippocampus

1988 • 165 citations

Rat hippocampal neurons in culture: voltage-clamp analysis of inhibitory synaptic connections

1984 • 165 citations

Stoichiometry of a recombinant GABAA receptor deduced from mutation-induced rectification

1993 • 164 citations

Differential activation of GABAA and GABAB receptors by spontaneously released transmitter

1992 • 156 citations

Inhibitory post‐synaptic currents in rat hippocampal CA1 neurones.

1984 • 155 citations

Functional diversity of GABA activated Cl− currents in Purkinje versus granule neurons in rat cerebellar slices

1994 • 142 citations

Halothane enhances tonic neuronal inhibition of elevating intracellular calcium

1991 • 135 citations

Synaptic localization of adrenergic disinhibition in the rat hippocampus

1991 • 123 citations

Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons

1993 • 122 citations

Patch-clamp recordings reveal powerful GABAergic inhibition in dentate hilar neurons

1994 • 115 citations

Assembly of GABAA receptor subunits: analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique

1993 • 110 citations

Pharmacological characterization of GABAB-mediated responses in the CA1 region of the rat hippocampal slice

1992 • 105 citations

Synaptic noise and multiquantal release at dendritic synapses

1993 • 104 citations

A subset of local interneurons generate slow inhibitory postsynaptic potentials in hippocampal neurons

1990 • 95 citations

The neurobiological basis of epilepsy

1992 • 90 citations

Nonstationary fluctuation analysis and direct resolution of single channel currents at postsynaptic sites

1991 • 75 citations

Acetylcholine receptor assembly is stimulated by phosphorylation of its γ subunit

1991 • 75 citations

Suppression of an Epileptiform Type of Electrocortical Activity in the Rat by Stimulation in the Vicinity of Locus Coeruleus

1977 • 72 citations

Synaptic and Nonsynaptic Localization of Benzodiazepine/GABA_A Receptor/Cl⁻ Channel Complex Using Monoclonal Antibodies in the Dorsal Lateral Geniculate Nucleus of the Cat

1990 • 67 citations

Synaptic Transmission Between Dissociated Adult Mammalian Neurons and Attached Synaptic Boutons

1988 • 60 citations

GABA?The quintessential neurotransmitter: Electroneutrality, fidelity, specificity, and a model for the ligand binding site of GABAA receptors

1993 • 51 citations

Large amplitude variability of GABAergic IPSCs in melanotropes from Xenopus laevis: evidence that quantal size differs between synapses

1994 • 38 citations

GABAergic synaptic current in dissociated nucleus basalis of Meynert neurons of the rat

1992 • 28 citations

Two classes of spontaneous GABA-mediated miniature synaptic currents in cultured rat hippocampal neurons

1992 • 14 citations

Variance analysis of gamma-aminobutyric acid (GABA)-ergic inhibitory postsynaptic currents from melanotropes of Xenopus laevis

1994 • 8 citations

Comparison of high-affinity binding of [3H]GABA to subcellular particles of rat brain and liver

1979 • 6 citations