Modulation of Basic Helix-Loop-Helix Transcription Complex Formation by Id Proteins during Neuronal Differentiation

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms

2000 • 1,761 citations

Control of endodermal endocrine development by Hes-1

2000 • 1,135 citations

Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons

1993 • 1,019 citations

Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND

1997 • 716 citations

Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects.

1995 • 702 citations

ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis

2000 • 671 citations

Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.

1992 • 667 citations

Mash1regulates neurogenesis in the ventral telencephalon

1999 • 631 citations

A Subclass of bHLH Proteins Required for Cardiac Morphogenesis

1995 • 544 citations

Basic helix-loop-helix genes in neural development

1997 • 521 citations

Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins

2000 • 504 citations

Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells.

1991 • 441 citations

An achaete-scute homologue essential for neuroendocrine differentiation in the lung

1997 • 439 citations

Id helix—loop—helix proteins in cell growth and differentiation

1998 • 413 citations

Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system.

1994 • 395 citations

The bHLH GeneHes1as a Repressor of the Neuronal Commitment of CNS Stem Cells

2000 • 311 citations

Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements.

1994 • 301 citations

Conservation of the Drosophila lateral inhibition pathway in human lung cancer: A hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression

1997 • 269 citations

Phenotypic changes of human neuroblastoma cells in culture induced by 12‐O‐tetradecanoyl‐phorbol‐13‐acetate

1981 • 255 citations

Id2 Specifically Alters Regulation of the Cell Cycle by Tumor Suppressor Proteins

1996 • 242 citations

Biology and Genetics of Human Neuroblastomas

1997 • 240 citations

Differential Interactions of Id Proteins with Basic-Helix-Loop-Helix Transcription Factors

1997 • 223 citations

A Role for Pref-1 and HES-1 in Thymocyte Development

2000 • 196 citations

Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization.

1991 • 161 citations

A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage.

1996 • 152 citations

The Groucho/Transducin-like Enhancer of split Transcriptional Repressors Interact with the Genetically Defined Amino-terminal Silencing Domain of Histone H3

1997 • 149 citations

Neural Crest Specification Regulated by the Helix-Loop-Helix Repressor Id2

1998 • 141 citations

Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells

1983 • 115 citations

Co-amplification of MYCN and a DEAD box gene (DDX1) in primary neuroblastoma.

1995 • 102 citations

Early Activation of Endogenous pp60^src Kinase Activity during Neuronal Differentiation of Cultured Human Neuroblastoma Cells

1990 • 83 citations

Detection and modulation in vivo of helix-loop-helix protein-protein interactions.

1993 • 73 citations

The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas.

1999 • 67 citations

Regulation of hippocampal neuronal differentiation by the basic helix-loop-helix transcription factors HES-1 and MASH-1

1999 • 63 citations

Early activation of endogenous pp60src kinase activity during neuronal differentiation of cultured human neuroblastoma cells.

1990 • 58 citations

Induced neuroblastoma cell differentiation, associated with transient HES-1 activity and reducedHASH-1 expression, is inhibited by Notch1

2000 • 55 citations

7 Neural Crest Diversification

1998 • 52 citations

Human Achaete-Scute Homologue 1 (HASH-1) Is Downregulated in Differentiating Neuroblastoma Cells

1999 • 49 citations

Relationships between extramacrochaetae and Notch signalling in Drosophila wing development

2000 • 36 citations