β1-integrin-mediated signaling essentially contributes to cell survival after radiation-induced genotoxic injury

Integrins

2002 • 8,127 citations

Integrin Signaling

1999 • 3,705 citations

Focal adhesion kinase: the first ten years

2003 • 1,360 citations

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

2003 • 1,168 citations

Analysis of gene function in somatic mammalian cells using small interfering RNAs

2002 • 1,108 citations

Regulation of cell adhesion and anchorage-dependent growth by a new β1-integrin-linked protein kinase

1996 • 1,106 citations

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

1997 • 1,050 citations

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: A mechanism for small cell lung cancer growth and drug resistance in vivo

1999 • 726 citations

NEW EMBO MEMBER'S REVIEW: Role of integrins in regulating epidermal adhesion, growth and differentiation

2002 • 616 citations

MAPK pathways in radiation responses

2003 • 589 citations

Biochemical signals and biological responses elicited by the focal adhesion kinase

2001 • 568 citations

Conformational Regulation of Integrin Structure and Function

2002 • 536 citations

Integrins and cell proliferation

2001 • 509 citations

NEW EMBO MEMBER'S REVIEW: The integrin-actin connection, an eternal love affair

2003 • 480 citations

Signaling through focal adhesion kinase

1997 • 468 citations

Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation

1997 • 433 citations

The influence of the microenvironment on the malignant phenotype

2000 • 398 citations

Integrin cytoplasmic interactions and bidirectional transmembrane signalling

1996 • 396 citations

Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2

1999 • 395 citations

Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility

2003 • 366 citations

Matrix Survival Signaling

2000 • 360 citations

Integrins, Oncogenes, and Anchorage Independence

1997 • 345 citations

Morphological appearance, growth behavior and migratory activity of human tumor cells maintained on extracellular matrix versus plastic

1980 • 312 citations

Integrin regulation of growth factor receptors

2002 • 295 citations

Integrin β Cytoplasmic Domains Differentially Bind to Cytoskeletal Proteins

1998 • 282 citations

Oxidative stress, redox, and the tumor microenvironment

2004 • 270 citations

Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts.

1995 • 254 citations

Ras GTPases: integrins' friends or foes?

2003 • 227 citations

Complex Formation with Focal Adhesion Kinase: A Mechanism to Regulate Activity and Subcellular Localization of Src Kinases

1999 • 201 citations

β1‐Integrins induce phosphorylation of Akt on serine 473 independently of focal adhesion kinase and Src family kinases

2004 • 195 citations

Cell Adhesion-Mediated Radioresistance (CAM-RR) Extracellular Matrix-Dependent Improvement of Cell Survival in Human Tumor and Normal Cells in Vitro

2003 • 124 citations

Focal Adhesion Targeting: The Critical Determinant of FAK Regulation and Substrate Phosphorylation

1999 • 116 citations

Irradiation differentially affects substratum-dependent survival, adhesion, and invasion of glioblastoma cell lines

2003 • 113 citations

It takes a tissue to make a tumor: epigenetics, cancer and the microenvironment.

2001 • 110 citations

Modulation of β1A Integrin Functions by Tyrosine Residues in the β1 Cytoplasmic Domain

1998 • 109 citations

The Cytoplasmic Tyrosines of Integrin Subunit β1 Are Involved in Focal Adhesion Kinase Activation

2000 • 95 citations

Regulation of Bcl-2 proteins during anoikis and amorphosis

2004 • 92 citations

Cell Adhesion Mediated Drug Resistance (CAM-DR): Role of Integrins and Resistance to Apoptosis in Human Myeloma Cell Lines

1999 • 90 citations

Antiapoptotic Action of Focal Adhesion Kinase (FAK) Against Ionizing Radiation

2002 • 79 citations

Cell adhesion to the extracellular matrix protein fibronectin modulates radiation-dependent G2 phase arrest involving integrin-linked kinase (ILK) and glycogen synthase kinase-3β (GSK-3β) in vitro

2003 • 78 citations

Overexpression of Hyperactive Integrin-Linked Kinase Leads to Increased Cellular Radiosensitivity

2004 • 63 citations

Expression of Integrin Subunit β1B in Integrin β1-Deficient GD25 Cells Does Not Interfere with αVβ3 Functions

2000 • 58 citations

Ionizing radiation modules of the expression and tyrosine phosphorylation of the focal adhesion‐associated proteins focal adhesion kinase (FAK) and its substrates p130cas and paxillin in A549 human lung carcinoma cellsin vitro

2003 • 47 citations

Differential Role of β_1Cand β_1AIntegrin Cytoplasmic Variants in Modulating Focal Adhesion Kinase, Protein Kinase B/AKT, and Ras/Mitogen-activated Protein Kinase Pathways

2000 • 46 citations

Splice variants of human beta 1 integrins origin biosynthesis and functions

2002 • 26 citations

Disruption of integrin-dependent adhesion and survival of endothelial cells by recombinant adenovirus expressing isolated β integrin cytoplasmic domains

2000 • 22 citations

Generality and the Need for More Focus

2002 • 1 citations