Inhibition of Hydroxymethylglutaryl-Coenzyme A Reductase Reduces Th1 Development and Promotes Th2 Development

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 • 8,631 citations

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease

1994 • 1,697 citations

Measurement of C-Reactive Protein for the Targeting of Statin Therapy in the Primary Prevention of Acute Coronary Events

2001 • 1,537 citations

INDUCTION OF TH1 AND TH2 CD4⁺T CELL RESPONSES:The Alternative Approaches

1997 • 1,464 citations

Statins as a newly recognized type of immunomodulator

2000 • 1,371 citations

Pleiotropic Effects of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors

2001 • 1,290 citations

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

2002 • 1,074 citations

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

2001 • 1,035 citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

1995 • 532 citations

A Novel Anti-Inflammatory Role for Simvastatin in Inflammatory Arthritis

2003 • 435 citations

TH1 and TH2 in Human Diseases

1996 • 390 citations

Effects of statins on vascular wall: vasomotor function, inflammation, and plaque stability

2000 • 377 citations

Blocking the CD40L-CD40 interaction in vivo specifically prevents the priming of T helper 1 cells through the inhibition of interleukin 12 secretion.

1996 • 349 citations

Atorvastatin reduces NF-κB activation and chemokine expression in vascular smooth muscle cells and mononuclear cells

1999 • 341 citations

Treatment of Relapsing Paralysis in Experimental Encephalomyelitis by Targeting Th1 Cells through Atorvastatin

2003 • 281 citations

Adjuvant-Guided Type-1 and Type-2 Immunity: Infectious/Noninfectious Dichotomy Defines the Class of Response

1999 • 260 citations

LFA-1 interaction with ICAM-1 and ICAM-2 regulates Th2 cytokine production.

1998 • 197 citations

Lovastatin inhibits proliferation of rat mesangial cells.

1993 • 173 citations

Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice

1997 • 168 citations

Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo.

1999 • 167 citations

Cutting Edge: LFA-1 Interaction with ICAM-1 and ICAM-2 Regulates Th2 Cytokine Production

1998 • 160 citations

Distinct Patterns of Membrane Microdomain Partitioning in Th1 and Th2 Cells

2001 • 157 citations

Recent advances in statins and the kidney

1999 • 151 citations

T helper subset development: roles of instruction, selection, and transcription

2002 • 147 citations

Preferential Role for NF-κB/Rel Signaling in the Type 1 But Not Type 2 T Cell-Dependent Immune Response In Vivo

1999 • 146 citations

CD4+ T cells specific to a glomerular basement membrane antigen mediate glomerulonephritis

2002 • 140 citations

T helper subset development: roles of instruction, selection, and transcription

2002 • 120 citations

Genetic Regulation of Commitment to Interleukin 4 Production by a CD4+ T Cell–intrinsic Mechanism

1998 • 104 citations

Simvastatin inhibits PDGF-induced DNA synthesis in human glomerular mesangial cells

1993 • 97 citations

Inhibition of human vascular smooth muscle cell proliferation by lovastatin: the role of isoprenoid intermediates of cholesterol synthesis

1994 • 89 citations

Human mesangial cell production of monocyte chemoattractant protein-1: Modulation by lovastatin

1995 • 72 citations

Polarization of Naive CD4+ T Cells Toward the Th1 Subset by CTLA-4 Costimulation

2000 • 70 citations

Lovastatin-induced inhibition of renal epithelial tubular cell proliferation involves a p21 activated, AP-1-dependent pathway

1997 • 70 citations

Effects of flwastatin on growth of porcine and human vascular smooth muscle cells in vitro

1995 • 48 citations

Indirect IL-4 Pathway in Type 1 Immunity

2002 • 38 citations

Expression and co-stimulatory function of B7-2 on murine CD4+ T cells

1998 • 32 citations

CD4+ T Cells Recognizing Specific Antigen Deposited in Glomeruli Cause Glomerulonephritis-like Kidney Injury

2002 • 23 citations

Possible Radical Scavenging Properties of Cicletanine and Renal Protection in Dahl Salt Sensitive Rats

1993 • 21 citations

CD43 polarization in unprimed T cells can be dissociated from raft coalescence by inhibition of HMG CoA reductase

2002 • 19 citations

Effects of the Anti-Platelet Aggregation Drug Dilazep on Cognitive Function in Dahl Salt-Sensitive Rats.

2003 • 3 citations