Desensitization of the muscarinic acetylcholine receptor of atrium in bullfrogs.

Chemical Nature of Synaptic Transmission in Vertebrates

1974 • 1,613 citations

A study of the ‘desensitization’ produced by acetylcholine at the motor end‐plate

1957 • 1,457 citations

A theory of drug action based on the rate of drug-receptor combination

1961 • 430 citations

Voltage clamp experiments on ventricular myocardial fibres

1970 • 255 citations

Zum Mechanismus der Membranwirkung des Acetylcholin an der Herzmuskelfaser

1958 • 247 citations

On the mechanism of desensitization at cholinergic receptors.

1970 • 247 citations

Generation and conduction of impulses in the heart as affected by drugs.

1963 • 233 citations

Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell

1978 • 200 citations

Dependence of acetylcholine desensitization on the membrane potential of frog muscle fibre and on the ionic changes in the medium

1970 • 172 citations

The Effect of Calcium on the Desensitization of Membrane Receptors at the Neuromuscular Junction

1966 • 163 citations

Factors in the Inactivation of Postjunctional Membrane Receptors of Frog Skeletal Muscle

1970 • 127 citations

Pharmacological receptors.

1968 • 107 citations

The effect of temperature on desensitization kinetics at the post‐synaptic membrane of the frog muscle fibre.

1975 • 95 citations

The action of acetylcholine on background conductance in frog atrial trabeculae.

1978 • 91 citations

Effects of acetylcholine and parasympathetic nerve stimulation on membrane potential in quiescent guinea‐pig atria.

1978 • 79 citations

The relationship between desensitization and the metaphilic effect at cholinergic receptors.

1970 • 60 citations

Desensitization and recovery at the frog neuromuscular junction.

1977 • 54 citations

Further Studies of the Effect of Calcium on the Time Course of Action of Carbamylcholine at the Neuromuscular Junction

1970 • 38 citations

Desensitization onset and recovery at the potassium-depolarized frog neuromuscular junction are voltage sensitive.

1978 • 37 citations

The effect of adrenaline on the electrogenic Na+ pump in cardiac muscle cells

1978 • 35 citations

EFFECTS OF EXTERNAL Na AND Ca ON THE MOUSE MYOMETRIUM IN RELATION TO THE EFFECTS OF OXYTOCIN AND CARBACHOL

1973 • 16 citations

DESENSITIZATION OF SMOOTH MUSCLE CELLS IN THE GUINEA PIG TAENIA COLI TO PROLONGED APPLICATION OF CARBACHOL

1973 • 13 citations

Desensitization of the muscarinic receptor of bullfrog atrial muscle

1980 • 10 citations

Desensitization in the rat myometrium

1972 • 8 citations

Activation of the electrogenic Na-pump of cardiac muscle fibres by ACh in K-free solutions

1979 • 4 citations

Inhibition of the ACh-induced extracurrent on atrial fibres of Rana esculenta by atropine and tetraethylammonium chloride [proceedings].

1979 • 4 citations