pH-dependent structural transitions of Alzheimer amyloid peptides

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1987 • 4,544 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

Amyloid Deposits and Amyloidosis

1980 • 1,787 citations

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

1984 • 1,633 citations

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

1990 • 1,388 citations

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

1986 • 1,387 citations

New insight into protein secondary structure from resolution-enhanced infrared spectra

1988 • 1,248 citations

Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease

1988 • 1,098 citations

Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity

1988 • 1,093 citations

A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors

1988 • 1,052 citations

Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels.

1985 • 1,025 citations

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

1988 • 920 citations

Evidence that β-Amyloid Protein in Alzheimer's Disease Is Not Derived by Normal Processing

1990 • 895 citations

Ubiquitin Is a Component of Paired Helical Filaments in Alzheimer's Disease

1987 • 834 citations

X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation.

1986 • 553 citations

Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants

1982 • 541 citations

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro.

1987 • 475 citations

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation.

1990 • 453 citations

“Cross-β” conformation in proteins

1968 • 392 citations

β-PLEATED SHEET FIBRILS A COMPARISON OF NATIVE AMYLOID WITH SYNTHETIC PROTEIN FIBRILS

1974 • 294 citations

Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic .beta.-protein fragments

1990 • 288 citations

Biochemistry of Altered Brain Proteins in Alzheimer's Disease

1989 • 261 citations

The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid.

1989 • 251 citations

In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to alzheimer's disease β-protein

1986 • 226 citations

Circular-dichroism studies on two murine serum amyloid A proteins

1988 • 168 citations

Ten to fourteen residue peptides of Alzheimer's disease protein are sufficient for amyloid fibril formation and its characteristic xray diffraction pattern

1987 • 154 citations

Morphology and antibody recognition of synthetic β‐amyloid peptides

1991 • 98 citations

Secondary structure prediction of human SAA1. Presumptive identification of calcium and lipid binding sites.

1986 • 71 citations

Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease.

1990 • 64 citations

Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease.

1990 • 62 citations

Structural studies with the uveopathogenic peptide M derived from retinal S-antigen

1990 • 48 citations

Ultrastructure of amyloid fibrils in Alzheimer’s disease and Down’s syndrome

1986 • 36 citations

X-ray scattering and diffraction by wet gels of AA amyloid fibrils.

1986 • 25 citations