Computational approaches to psychiatry

The free-energy principle: a unified brain theory?

2010 • 6,134 citations

Dynamic causal modelling

2003 • 4,412 citations

Toward the future of psychiatric diagnosis: the seven pillars of RDoC

2013 • 2,705 citations

The Bayesian brain: the role of uncertainty in neural coding and computation

2004 • 2,318 citations

Discrete Coding of Reward Probability and Uncertainty by Dopamine Neurons

2003 • 2,034 citations

By Carrot or by Stick: Cognitive Reinforcement Learning in Parkinsonism

2004 • 1,951 citations

Model-Based Influences on Humans' Choices and Striatal Prediction Errors

2011 • 1,716 citations

Uncertainty, Neuromodulation, and Attention

2005 • 1,676 citations

Bayesian model selection for group studies

2009 • 1,408 citations

Perceiving is believing: a Bayesian approach to explaining the positive symptoms of schizophrenia

2008 • 1,337 citations

A free energy principle for the brain

2006 • 1,251 citations

The Helmholtz Machine

1995 • 1,167 citations

States versus Rewards: Dissociable Neural Prediction Error Signals Underlying Model-Based and Model-Free Reinforcement Learning

2010 • 1,152 citations

Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?

2012 • 946 citations

Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

2011 • 932 citations

A causal link between prediction errors, dopamine neurons and learning

2013 • 870 citations

Synaptic Plasticity and Dysconnection in Schizophrenia

2006 • 826 citations

Computational psychiatry

2011 • 727 citations

From reinforcement learning models to psychiatric and neurological disorders

2011 • 698 citations

Rational regulation of learning dynamics by pupil-linked arousal systems

2012 • 687 citations

Modulators of decision making

2008 • 611 citations

A Bayesian foundation for individual learning under uncertainty

2011 • 592 citations

The Rupture and Repair of Cooperation in Borderline Personality Disorder

2008 • 591 citations

Identifying Neural Drivers with Functional MRI: An Electrophysiological Validation

2008 • 531 citations

An Approximately Bayesian Delta-Rule Model Explains the Dynamics of Belief Updating in a Changing Environment

2010 • 503 citations

Neural Basis of Reinforcement Learning and Decision Making

2012 • 502 citations

Pupil dilation signals surprise: evidence for noradrenaline’s role in decision making

2011 • 486 citations

Generative Models of Cortical Oscillations: Neurobiological Implications of the Kuramoto Model

2010 • 465 citations

Bonsai Trees in Your Head: How the Pavlovian System Sculpts Goal-Directed Choices by Pruning Decision Trees

2012 • 426 citations

Toward a neurobiology of delusions

2010 • 371 citations

The ubiquity of model-based reinforcement learning

2012 • 366 citations

Mechanisms of Hierarchical Reinforcement Learning in Corticostriatal Circuits 1: Computational Analysis

2011 • 329 citations

Hierarchical Prediction Errors in Midbrain and Basal Forebrain during Sensory Learning

2013 • 328 citations

Learning latent structure: carving nature at its joints

2010 • 311 citations

Comparing Dynamic Causal Models using AIC, BIC and Free Energy

2011 • 299 citations

Emotional Valence and the Free-Energy Principle

2013 • 284 citations

Diagnostic neuroimaging across diseases

2011 • 265 citations

Risk, Unexpected Uncertainty, and Estimation Uncertainty: Bayesian Learning in Unstable Settings

2011 • 249 citations

Linking Microcircuit Dysfunction to Cognitive Impairment: Effects of Disinhibition Associated with Schizophrenia in a Cortical Working Memory Model

2012 • 248 citations

The Neural Representation of Unexpected Uncertainty during Value-Based Decision Making

2013 • 245 citations

NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia

2012 • 244 citations

Explicit neural signals reflecting reward uncertainty

2008 • 224 citations

Hierarchical reinforcement learning and decision making

2012 • 221 citations

Reduced Prefrontal-Parietal Effective Connectivity and Working Memory Deficits in Schizophrenia

2012 • 203 citations

Twenty-Five Lessons from Computational Neuromodulation

2012 • 172 citations

Dissecting psychiatric spectrum disorders by generative embedding

2013 • 171 citations

Generative Embedding for Model-Based Classification of fMRI Data

2011 • 168 citations

Observing the Observer (I): Meta-Bayesian Models of Learning and Decision-Making

2010 • 158 citations

Modelling Trial-by-Trial Changes in the Mismatch Negativity

2013 • 158 citations

Spatial Attention, Precision, and Bayesian Inference: A Study of Saccadic Response Speed

2013 • 148 citations

An In Vivo Assay of Synaptic Function Mediating Human Cognition

2011 • 139 citations

Computational and dynamic models in neuroimaging

2009 • 128 citations

Bayesian modelling of Jumping-to-Conclusions bias in delusional patients

2011 • 126 citations

Genetic Predictors of Response to Serotonergic and Noradrenergic Antidepressants in Major Depressive Disorder: A Genome-Wide Analysis of Individual-Level Data and a Meta-Analysis

2012 • 124 citations

Multiple representations and algorithms for reinforcement learning in the cortico-basal ganglia circuit

2011 • 122 citations

Neuroeconomic Approaches to Mental Disorders

2010 • 119 citations

Are computational models of any use to psychiatry?

2011 • 103 citations

Modeling Ketamine Effects on Synaptic Plasticity During the Mismatch Negativity

2012 • 102 citations

How to set the switches on this thing

2012 • 100 citations

Cooperation and Heterogeneity of the Autistic Mind

2010 • 98 citations

A common mechanism for adaptive scaling of reward and novelty

2010 • 94 citations

Smooth Pursuit and Visual Occlusion: Active Inference and Oculomotor Control in Schizophrenia

2012 • 91 citations

Brain Connectivity Abnormalities Predating the Onset of Psychosis

2013 • 91 citations

Dynamic Causal Models and Physiological Inference: A Validation Study Using Isoflurane Anaesthesia in Rodents

2011 • 89 citations

Disordered Corticolimbic Interactions During Affective Processing in Children and Adolescents at Risk for Schizophrenia Revealed by Functional Magnetic Resonance Imaging and Dynamic Causal Modeling

2012 • 60 citations

A computational neuroscience approach to schizophrenia and its onset

2010 • 59 citations

The application of nonlinear Dynamic Causal Modelling for fMRI in subjects at high genetic risk of schizophrenia

2013 • 48 citations

Model-based dynamical analysis of functional disconnection in schizophrenia

2011 • 41 citations

Separate encoding of model-based and model-free valuations in the human brain

2011 • 39 citations

A switching multi-scale dynamical network model of EEG/MEG

2013 • 26 citations

Deleted Work

1955 • 0 citations