Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

Factor structure of the barratt impulsiveness scale

1995 • 7,247 citations

The Yale-Brown Obsessive Compulsive Scale

1989 • 7,156 citations

Neural systems of reinforcement for drug addiction: from actions to habits to compulsion

2005 • 3,624 citations

The Yale-Brown Obsessive-Compulsive Scale: Measures of internal consistency

1994 • 2,415 citations

Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action

2009 • 1,642 citations

Context, ambiguity, and unlearning: sources of relapse after behavioral extinction

2002 • 1,567 citations

Impulsivity, Compulsivity, and Top-Down Cognitive Control

2011 • 1,466 citations

The primate basal ganglia: parallel and integrative networks

2003 • 1,439 citations

Impulsivity and Inhibitory Control

1997 • 1,366 citations

Impulsivity as a determinant and consequence of drug use: a review of underlying processes

2008 • 1,328 citations

Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake

2007 • 1,250 citations

Intermediate phenotypes and genetic mechanisms of psychiatric disorders

2006 • 1,210 citations

Actions and habits: the development of behavioural autonomy

1985 • 1,156 citations

Abnormal and normal obsessions

1978 • 1,138 citations

Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: The orbitofronto-striatal model revisited

2007 • 1,127 citations

Comorbidity of Anxiety Disorders With Anorexia and Bulimia Nervosa

2004 • 1,094 citations

Animal intelligence; experimental studies

1911 • 1,086 citations

How can drug addiction help us understand obesity?

2005 • 1,065 citations

Practice Guideline for the Treatment of Patients With Obsessive-Compulsive Disorder

2008 • 977 citations

Randomized, Placebo-Controlled Trial of Exposure and Ritual Prevention, Clomipramine, and Their Combination in the Treatment of Obsessive-Compulsive Disorder

2004 • 966 citations

Cognitive Behavioural Processes across Psychological Disorders: A Transdiagnostic Approach to Research and Treatment

2004 • 959 citations

The role of impulsivity in the development of substance use and eating disorders

2004 • 912 citations

Low Level of Brain Dopamine D₂ Receptors in Methamphetamine Abusers: Association With Metabolism in the Orbitofrontal Cortex

2001 • 901 citations

Animal Intelligence. Experimental Studies

1912 • 850 citations

Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder

1998 • 823 citations

Behavioral models of impulsivity in relation to ADHD: Translation between clinical and preclinical studies

2006 • 809 citations

Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology

2008 • 776 citations

The role of impulsive behavior in drug abuse

2008 • 773 citations

The dual pathway model of AD/HD: an elaboration of neuro-developmental characteristics

2003 • 767 citations

A specific role for posterior dorsolateral striatum in human habit learning

2009 • 728 citations

Heroin and cocaine abusers have higher discount rates for delayed rewards than alcoholics or non‐drug‐using controls

2004 • 705 citations

Revision of the Padua Inventory of obsessive compulsive disorder symptoms: Distinctions between worry, obsessions, and compulsions

1996 • 659 citations

Behavior Therapy for Children With Tourette Disorder

2010 • 649 citations

The ecological validity of delay aversion and response inhibition as measures of impulsivity in AD/HD: a supplement to the NIMH multimodal treatment study of AD/HD.

2001 • 629 citations

Distinct basal ganglia territories are engaged in early and advanced motor sequence learning

2005 • 613 citations

Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients

2002 • 601 citations

A systematic review: antipsychotic augmentation with treatment refractory obsessive-compulsive disorder

2006 • 596 citations

Inhibitory control and psychopathology: A meta-analysis of studies using the stop signal task

2010 • 562 citations

Preference for Immediate over Delayed Rewards Is Associated with Magnitude of Ventral Striatal Activity

2006 • 559 citations

Disruption in the Balance Between Goal-Directed Behavior and Habit Learning in Obsessive-Compulsive Disorder

2011 • 552 citations

Orbitofrontal Dysfunction in Patients with Obsessive-Compulsive Disorder and Their Unaffected Relatives

2008 • 531 citations

Abnormal Brain Structure Implicated in Stimulant Drug Addiction

2012 • 530 citations

Why obese children cannot resist food: The role of impulsivity

2005 • 517 citations

Motor Inhibition and Cognitive Flexibility in Obsessive-Compulsive Disorder and Trichotillomania

2006 • 515 citations

Effect of television advertisements for foods on food consumption in children

2004 • 512 citations

Brain abnormalities in human obesity: A voxel-based morphometric study

2006 • 511 citations

Similarity Between Obesity and Drug Addiction as Assessed by Neurofunctional Imaging

2004 • 500 citations

Compulsive overeating as an addiction disorder. A review of theory and evidence

2009 • 464 citations

The endophenotype concept in psychiatric genetics

2006 • 454 citations

Understanding the role of impulsivity and externalizing psychopathology in alcohol abuse: Application of the UPPS Impulsive Behavior Scale.

2003 • 443 citations

Neurocognitive endophenotypes of obsessive-compulsive disorder

2007 • 429 citations

Genetic Theorizing and Schizophrenia

1973 • 415 citations

Drug Addiction Endophenotypes: Impulsive Versus Sensation-Seeking Personality Traits

2010 • 409 citations

The impulsive client: Theory, research, and treatment.

1993 • 408 citations

Impaired Cognitive Flexibility and Motor Inhibition in Unaffected First-Degree Relatives of Patients With Obsessive-Compulsive Disorder

2007 • 391 citations

Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence

2011 • 391 citations

Associative theories of goal-directed behaviour: a case for animal–human translational models

2009 • 386 citations

Similar Effects of the Selective Noradrenaline Reuptake Inhibitor Atomoxetine on Three Distinct Forms of Impulsivity in the Rat

2007 • 358 citations

Inverse Association Between BMI and Prefrontal Metabolic Activity in Healthy Adults

2008 • 338 citations

A Functional Neuroanatomy of Tics in Tourette Syndrome

2000 • 334 citations

Disinhibited Eating in Obese Adolescents Is Associated With Orbitofrontal Volume Reductions and Executive Dysfunction

2011 • 329 citations

Should an obsessive-compulsive spectrum grouping of disorders be included in DSM-V?

2010 • 324 citations

Cortical Development in Typically Developing Children With Symptoms of Hyperactivity and Impulsivity: Support for a Dimensional View of Attention Deficit Hyperactivity Disorder

2010 • 299 citations

Atomoxetine Improved Response Inhibition in Adults with Attention Deficit/Hyperactivity Disorder

2007 • 276 citations

Initial validation of two opiate craving questionnaires

2002 • 273 citations

Early versus late onset obsessive–compulsive disorder: Evidence for distinct subtypes

2011 • 258 citations

Safety behaviours preserve threat beliefs: Protection from extinction of human fear conditioning by an avoidance response

2009 • 258 citations

Of human bondage

2002 • 258 citations

Lesions of the Medial Striatum in Monkeys Produce Perseverative Impairments during Reversal Learning Similar to Those Produced by Lesions of the Orbitofrontal Cortex

2008 • 254 citations

Is obsessive–compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective

2011 • 250 citations

Conducting exposure treatment in multiple contexts can prevent relapse

1998 • 210 citations

Executive function in Tourette's syndrome and obsessive–compulsive disorder

2004 • 210 citations

Differential Engagement of the Ventromedial Prefrontal Cortex by Goal-Directed and Habitual Behavior toward Food Pictures in Humans

2009 • 194 citations

Stress, habits, and drug addiction: A psychoneuroendocrinological perspective.

2011 • 187 citations

Low level of dopaminergic D2 receptor binding in obsessive-compulsive disorder

2004 • 186 citations

Deficient Activity in the Neural Systems That Mediate Self-regulatory Control in Bulimia Nervosa

2009 • 182 citations

Behavioural characterisation of high impulsivity on the 5-choice serial reaction time task: Specific deficits in ‘waiting’ versus ‘stopping’

2008 • 179 citations

The role of the orbitofrontal cortex in normally developing compulsive-like behaviors and obsessive–compulsive disorder

2004 • 177 citations

Frontal Responses During Learning Predict Vulnerability to the Psychotogenic Effects of Ketamine

2006 • 177 citations

Impulse control disorders in Parkinson's disease

2011 • 175 citations

Executive Dysfunctions in Obsessive-Compulsive Patients and Unaffected Relatives: Searching for a New Intermediate Phenotype

2010 • 165 citations

Monoamine Oxidase-A Genetic Variations Influence Brain Activity Associated with Inhibitory Control: New Insight into the Neural Correlates of Impulsivity

2005 • 164 citations

The comorbidity of substance use disorders and eating disorders in women: Prevalence, etiology, and treatment

2009 • 159 citations

Obesity and Its Relationship to Addictions: Is Overeating a Form of Addictive Behavior?

2009 • 130 citations

Response Perseveration in Stimulant Dependence Is Associated with Striatal Dysfunction and Can Be Ameliorated by a D2/3 Receptor Agonist

2011 • 125 citations

Impaired goal-directed behavioural control in human impulsivity

2010 • 123 citations

Food, eating, and weight concerns of men in recovery from substance addiction

2007 • 122 citations

Treatment of Tics and Tourette Syndrome

2010 • 121 citations

Regional grey matter volume abnormalities in bulimia nervosa and binge-eating disorder

2009 • 114 citations

Test meal intake in obese binge eaters in relation to impulsivity and compulsivity

2007 • 114 citations

Recurrent overeating: An empirical comparison of binge eating disorder, bulimia nervosa, and obesity

1993 • 112 citations

The Oxford Handbook of Impulse Control Disorders

2011 • 106 citations

Impaired Cognitive Flexibility and Motor Inhibition in Unaffected First-Degree Relatives of Patients With Obsessive-Compulsive Disorder

2007 • 104 citations

Clinical trials in psychiatry

1983 • 103 citations

Extinction of drug- and withdrawal-paired cues in animal models: Relevance to the treatment of addiction

2010 • 102 citations

Myth of the pure obsessional type in obsessive-compulsive disorder

2011 • 100 citations

Striving for Coherence

2005 • 99 citations

Impulsivity and compulsivity in bulimia nervosa

2005 • 95 citations

Children with very early onset obsessive-compulsive disorder: clinical features and treatment outcome

2011 • 86 citations

Opportunities and Challenges of Psychiatric Drug Discovery: Roles for Scientists in Academic, Industry, and Government Settings

2008 • 82 citations

The neuropsychology of the schizo-obsessive subtype of schizophrenia: a new analysis

2009 • 80 citations

Adolescents At Risk for Alcohol Abuse Demonstrate Altered Frontal Lobe Activation During Stroop Performance

2010 • 77 citations

Brain functional connectivity in stimulant drug dependence and obsessive–compulsive disorder

2011 • 72 citations

Symptom Dimensions in Obsessive-Compulsive Disorder:Implications for theDSM-V

2007 • 71 citations

Association Between Attention-Deficit/Hyperactivity Disorder in Adolescence and Substance Use Disorders in Adulthood

2010 • 67 citations

A UK strategy for mental health and wellbeing

2010 • 45 citations

Neural correlates of choice behavior related to impulsivity and venturesomeness

2011 • 41 citations

Implications of compulsive and impulsive traits for serotonin status in women with bulimia nervosa

2003 • 27 citations

Obsessive-Compulsive Disorder Among Patients Entering Substance Abuse Treatment

1994 • 25 citations

Is Obsessive-Compulsive Disorder an Anxiety Disorder, and what, if any, are Spectrum Conditions? A family-study perspective

2011 • 16 citations