Maturation and Maintenance of the Neuromuscular Synapse

Dystrophin: The protein product of the duchenne muscular dystrophy locus

1987 • 4,477 citations

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

1996 • 1,589 citations

DEVELOPMENT OF THE VERTEBRATE NEUROMUSCULAR JUNCTION

1999 • 1,485 citations

Membrane organization of the dystrophin-glycoprotein complex

1991 • 1,321 citations

Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice

1996 • 915 citations

The Receptor Tyrosine Kinase MuSK Is Required for Neuromuscular Junction Formation In Vivo

1996 • 881 citations

Utrophin-Dystrophin-Deficient Mice as a Model for Duchenne Muscular Dystrophy

1997 • 710 citations

The Agrin Hypothesis

1990 • 637 citations

Skeletal and Cardiac Myopathies in Mice Lacking Utrophin and Dystrophin: A Model for Duchenne Muscular Dystrophy

1997 • 625 citations

Failure of postsynaptic specialization to develop at neuromuscular junctions of rapsyn-deficient mice

1995 • 530 citations

Dystroglycan Is Essential for Early Embryonic Development: Disruption of Reichert's Membrane in Dag1-Null Mice

1997 • 529 citations

Dystroglycan-α, a dystrophin-associated glycoprotein, is a functional agrin receptor

1994 • 509 citations

Distribution and Function of Laminins in the Neuromuscular System of Developing, Adult, and Mutant Mice

1997 • 433 citations

Localization of dystrophin to postsynaptic regions of central nervous system cortical neurons

1990 • 413 citations

Quantitation of junctional and extrajunctional acetylcholine receptors by electron microscope autoradiography after (125)I-α-bungarotoxin binding at mouse neuromuscular junctions

1976 • 398 citations

A Role for Dystroglycan in Basement Membrane Assembly

1998 • 387 citations

Muscular dystrophies and the dystrophin–glycoprotein complex

1997 • 379 citations

A role for dystrophin-associated glycoproteins and utrophin in agrin-induced AChR clustering

1994 • 369 citations

Muscle Cell Differentiation of Embryonic Stem Cells Reflects Myogenesis in Vivo: Developmentally Regulated Expression of Myogenic Determination Genes and Functional Expression of Ionic Currents

1994 • 369 citations

Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle

1991 • 368 citations

Progressive Muscular Dystrophy in α-Sarcoglycan–deficient Mice

1998 • 351 citations

Role for α-dystrobrevin in the pathogenesis of dystrophin-dependent muscular dystrophies

1999 • 309 citations

Identification and purification of an agrin receptor from torpedo postsynaptic membranes: A heteromeric complex related to the dystroglycans

1994 • 307 citations

The ability of agrin to cluster AChRs depends on alternative splicing and on cell surface proteoglycans

1993 • 305 citations

γ-Sarcoglycan Deficiency Leads to Muscle Membrane Defects and Apoptosis Independent of Dystrophin

1998 • 287 citations

Dystroglycan inside and out

1999 • 282 citations

Dystroglycan binds nerve and muscle agrin

1994 • 272 citations

Differential Association of Syntrophin Pairs with the Dystrophin Complex

1997 • 237 citations

Alternatively Spliced Isoforms of Nerve- and Muscle-Derived Agrin

1999 • 236 citations

From dystrophinopathy to sarcoglycanopathy: Evolution of a concept of muscular dystrophy

1998 • 235 citations

Alternative Splicing of Agrin Alters Its Binding to Heparin, Dystroglycan, and the Putative Agrin Receptor

1996 • 223 citations

Subtle Neuromuscular Defects in Utrophin-deficient Mice

1997 • 216 citations

Postsynaptic Abnormalities at the Neuromuscular Junctions of Utrophin-deficient Mice

1997 • 215 citations

Rapsyn may function as a link between the acetylcholine receptor and the agrin-binding dystrophin-associated glycoprotein complex

1995 • 209 citations

Dystrobrevin and dystrophin: An interaction through coiled-coil motifs

1997 • 202 citations

Increasing complexity of the dystrophin-associated protein complex.

1994 • 194 citations

The formation of neuromuscular synapses

1998 • 189 citations

Structure and function of the neuromuscular junction in young adultmdx mice

1991 • 179 citations

Isoform Diversity of Dystrobrevin, the Murine 87-kDa Postsynaptic Protein

1996 • 158 citations

The 87K postsynaptic membrane protein from torpedo is a protein-tyrosine kinase substrate homologous to dystrophin

1993 • 158 citations

Postnatal maturation of nerve-muscle junctions in hindlimb muscles of the mouse

1982 • 153 citations

β-dystrobrevin, a member of the dystrophin-related protein family

1998 • 153 citations

Developmental changes in acetylcholine receptor aggregates at rat skeletal neuromuscular junctions

1981 • 153 citations

Evidence for in Situ and in VitroAssociation between β-Dystroglycan and the Subsynaptic 43K Rapsyn Protein

1998 • 144 citations

Regulation of agrin-induced acetylcholine receptor aggregation by Ca++ and phorbol ester.

1988 • 130 citations

Cloning and characterization of the human homologue of a dystrophin related phosphoprotein found at the Torpedo electric organ post- synaptic membrane

1996 • 128 citations

β2-Syntrophin

1994 • 127 citations

Differential Membrane Localization and Intermolecular Associations of α-Dystrobrevin Isoforms in Skeletal Muscle

1998 • 124 citations

α-Dystroglycan Is a Laminin Receptor Involved in Extracellular Matrix Assembly on Myotubes and Muscle Cell Viability

1999 • 119 citations

A synapse-specific carbohydrate at the neuromuscular junction: association with both acetylcholinesterase and a glycolipid

1988 • 116 citations

Integrins mediate adhesion to agrin and modulate agrin signaling

1997 • 115 citations

β-Dystrobrevin, a New Member of the Dystrophin Family

1997 • 107 citations

A novel 87,000-Mr protein associated with acetylcholine receptors in Torpedo electric organ and vertebrate skeletal muscle.

1989 • 100 citations

Distinct phenotypes of mutant mice lacking agrin, MuSK, or rapsyn

1999 • 93 citations

Characterisation of α-dystrobrevin in muscle

1998 • 90 citations

Progressive Muscular Dystrophy

1961 • 90 citations

Deficient development and maintenance of postsynaptic specializations in mutant mice lacking an ‘adult’ acetylcholine receptor subunit

1997 • 89 citations

Agrin Binding to α-Dystroglycan

1996 • 81 citations

Role for a synapse-specific carbohydrate in agrin-induced clustering of acetylcholine receptors

1995 • 80 citations

Alternative RNA splicing that determines agrin activity regulates binding to heparin and α-dystroglycan

1996 • 75 citations

alpha-Dystroglycan functions in acetylcholine receptor aggregation but is not a coreceptor for agrin-MuSK signaling.

1998 • 73 citations

Dystrophin and beta‐dystroglycan in photoreceptor terminals from normal and mdx^3Cv mouse retinae

1999 • 61 citations

α-Dystroglycan Functions in Acetylcholine Receptor Aggregation But Is Not a Coreceptor for Agrin-MuSK Signaling

1998 • 59 citations

Formation of Postsynaptic-Like Membranes during Differentiation of Embryonic Stem Cellsin Vitro

1998 • 46 citations

Characterization of the tyrosine phosphorylation and distribution of dystrobrevin isoforms

1998 • 42 citations

Inhibition of agrin‐mediated acetylcholine receptor clustering by utrophin C‐terminal peptides

1996 • 9 citations