Linkage of Faulty Major Histocompatibility Complex Class I to Autoimmune Diabetes

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

ISLET-CELL ANTIBODIES IN DIABETES MELLITUS WITH AUTOIMMUNE POLYENDOCRINE DEFICIENCIES

1974 • 1,463 citations

Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

1983 • 1,078 citations

β2-Microglobulin deficient mice lack CD4−8+ cytolytic T cells

1990 • 997 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

1990 • 775 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

Termination of Pregnancy on Psychiatric Grounds

1964 • 683 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

1982 • 531 citations

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity

1991 • 474 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

The NOD Mouse: Recessive Diabetogenic Gene in the Major Histocompatibility Complex

1986 • 424 citations

Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter

1991 • 413 citations

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study.

1988 • 387 citations

Islet-Cell-Surface Antibodies in Juvenile Diabetes Mellitus

1978 • 356 citations

Analysis of HLA-DQ Genotypes and Susceptibility in Insulin-Dependent Diabetes Mellitus

1990 • 335 citations

ANTIBODIES TO PANCREATIC ISLET CELLS IN INSULIN-DEPENDENT DIABETICS WITH COEXISTENT AUTOIMMUNE DISEASE

1974 • 329 citations

Immunology of Insulin-Dependent Diabetes Mellitus

1985 • 240 citations

Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping

1989 • 238 citations

First-Degree Relatives of Patients with Type I Diabetes Mellitus

1985 • 226 citations

Inactivating the beta 2-microglobulin locus in mouse embryonic stem cells by homologous recombination.

1989 • 216 citations

Class discrimination in the world of immunology

1987 • 214 citations

Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice

1990 • 203 citations

Defective activation of T suppressor cell function in nonobese diabetic mice. Potential relation to cytokine deficiencies.

1988 • 199 citations

Competitive Insulin Autoantibody Assay: Prospective Evaluation of Subjects at High Risk for Development of Type I Diabetes Mellitus

1987 • 181 citations

New HLA DNA polymorphisms associated with autoimmune diseases

1986 • 135 citations

Differential Sensitivity to β-Cell Secretagogues in “Early,” Type I Diabetes Mellitus

1984 • 112 citations

A trans-acting major histocompatibility complex-linked gene whose alleles determine gain and loss changes in the antigenic structure of a classical class I molecule.

1989 • 94 citations

Progress Toward Standardization of Cytoplasmic Islet Cell–Antibody Assay

1987 • 87 citations

HLA-DQβ Sequence Polymorphism and Genetic Susceptibility to IDDM

1990 • 70 citations

Abnormal T-Lymphocyte Subsets in Type I Diabetes

1989 • 65 citations

Genetic Analysis for Insulitis in NOD Mice

1985 • 56 citations

Assay for Islet Cell Antibodies: Protein A—Monoclonal Antibody Method

1985 • 50 citations

HLA-DQ rather than HLA-DR region might be involved in dominant nonsusceptibility to diabetes.

1988 • 50 citations

Transgenic cereals by direct injection of DNA into plants

1987 • 22 citations

Assay for Islet Cell Antibodies With Rat Pancreas and Peroxidase Protein A

1988 • 16 citations