Structure of isocitrate dehydrogenase with isocitrate, nicotinamide adenine dinucleotide phosphate, and calcium at 2.5-.ANG. resolution: A pseudo-Michaelis ternary complex

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

A graphics model building and refinement system for macromolecules

1978 • 1,858 citations

Structure of calmodulin refined at 2.2 Å resolution

1988 • 1,019 citations

CRYSTAL STRUCTURES OF THE HELIX-LOOP-HELIX CALCIUM-BINDING PROTEINS

1989 • 855 citations

Structure of the calcium regulatory muscle protein troponin-C at 2.8 Å resolution

1985 • 619 citations

Refinement of the structure of carp muscle calcium-binding parvalbumin by model building and difference fourier analysis

1975 • 433 citations

Structure of a triclinic ternary complex of horse liver alcohol dehydrogenase at 2.9 Å resolution

1981 • 373 citations

Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase.

1975 • 330 citations

A restrained-parameter thermal-factor refinement procedure

1980 • 312 citations

Structure of vitamin D-dependent calcium-binding protein from bovine intestine

1981 • 309 citations

Inactivation of isocitrate dehydrogenase by phosphorylation is mediated by the negative charge of the phosphate.

1987 • 300 citations

Regulation of an Enzyme by Phosphorylation at the Active Site

1990 • 246 citations

Catalytic mechanism of NADP+-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes

1991 • 244 citations

Crystallographic investigations of nicotinamide adenine dinucleotide binding to horse liver alcohol dehydrogenase

1984 • 235 citations

Structure of Lactate Dehydrogenase at 2.8 Å Resolution

1970 • 234 citations

A protein with kinase and phosphatase activities involved in regulation of tricarboxylic acid cycle

1982 • 212 citations

Structure of the active ternary complex of pig heart lactate dehydrogenase with S-lac-NAD at 2.7 Å resolution

1981 • 209 citations

Structure of a bacterial enzyme regulated by phosphorylation, isocitrate dehydrogenase.

1989 • 205 citations

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase

1992 • 193 citations

Refined crystal structure of cytoplasmic malate dehydrogenase at 2.5-.ANG. resolution

1989 • 149 citations

Synthesis of C4-dicarboxylic acids from acetate by a “glyoxylate bypass” of the tricarboxylic acid cycle

1957 • 148 citations

Compensatory phosphorylation of isocitrate dehydrogenase. A mechanism for adaptation to the intracellular environment.

1985 • 139 citations

Electrostatic and Steric Contributions to Regulation at the Active Site of Isocitrate Dehydrogenase

1990 • 118 citations

Manganese-containing superoxide dismutase from Escherichia coli: Reversible resolution and metal replacements

1979 • 95 citations

NADP+-specific isocitrate dehydrogenase of Escherichia coli

1972 • 90 citations

Regulation of isocitrate dehydrogenase by phosphorylation involves no long-range conformational change in the free enzyme.

1990 • 85 citations

Structure of the medium-chain acyl-CoA dehydrogenase from pig liver mitochondria at 3-A resolution.

1988 • 77 citations

Demography of Northern Elephant Seals, 1911-1982

1983 • 58 citations

An unusual conformation of NAD+ bound to sorbitoldehydrogenase?

1984 • 32 citations

Conformational Variability of NAD ⁺ in the Free and Bound States: a Nicotinamide Sandwich in NAD ⁺ Crystals

1984 • 23 citations