A Discrete Site Modulates Activation of I Domains

Stimulation of the adherence of neutrophils to umbilical vein endothelium by human recombinant tumor necrosis factor.

1985 • 1,056 citations

Crystal structure of the A domain from the a subunit of integrin CR3 (CD11 b/CD18)

1995 • 893 citations

A Polymorphism of a Platelet Glycoprotein Receptor as an Inherited Risk Factor for Coronary Thrombosis

1996 • 707 citations

The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

1993 • 546 citations

Platelet plasma membrane glycoproteins. Evidence for the presence of nonequivalent disulfide bonds using nonreduced-reduced two-dimensional gel electrophoresis.

1977 • 451 citations

Contributions of the Mac-1 glycoprotein family to adherence-dependent granulocyte functions: structure-function assessments employing subunit-specific monoclonal antibodies.

1986 • 423 citations

Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils.

1990 • 421 citations

Two conformations of the integrin A-domain (I-domain): a pathway for activation?

1995 • 400 citations

Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen.

1988 • 374 citations

Crystal structure of the I-domain from the CD11a/CD18 (LFA-1, alpha L beta 2) integrin.

1995 • 308 citations

Von Willebrand Disease: A Database of Point Mutations, Insertions, and Deletions

1993 • 215 citations

The Mac-1 and p150,95 β2 integrins bind denatured proteins to mediate leukocyte cell-substrate adhesion

1992 • 214 citations

Amino acid sequence studies on artiodactyl fibrinopeptides

1967 • 197 citations

Identification of the complement iC3b binding site in the beta 2 integrin CR3 (CD11b/CD18).

1994 • 184 citations

Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes

1982 • 176 citations

Identification of Amino Acid Residues Essential for von Willebrand Factor Binding to Platelet Glycoprotein Ib.

1995 • 143 citations

Identification of discontinuous von Willebrand factor sequences involved in complex formation with botrocetin. A model for the regulation of von Willebrand factor binding to platelet glycoprotein Ib.

1991 • 135 citations

Differential ligand binding specificities of recombinant CD11b/CD18 integrin I-domain.

1994 • 135 citations

Functional interaction between the integrin antagonist neutrophil inhibitory factor and the I domain of CD11b/CD18

1994 • 128 citations

The leukocyte integrin p150,95 (CD11c/CD18) as a receptor for iC3b. Activation by a heterologous beta subunit and localization of a ligand recognition site to the I domain.

1994 • 118 citations

Overlapping, but Not Identical, Sites Are Involved in the Recognition of C3bi, Neutrophil Inhibitory Factor, and Adhesive Ligands by the αMβ2 Integrin

1996 • 91 citations

Antibodies that activate β2 integrins can generate different ligand binding states

1995 • 64 citations

Neutrophil inhibitory factor prevents neutrophil-dependent lung injury.

1995 • 57 citations

Cytoplasmic tails of human complement receptor type 3 (CR3, CD11b/ CD18) regulate ligand avidity and the internalization of occupied receptors.

1993 • 55 citations

A .gamma.-carboxyglutamic acid (.gamma.) variant (.gamma.6D, .gamma.7D) of human activated protein C displays greatly reduced activity as an anticoagulant

1990 • 53 citations

Cytoplasmic tails of human complement receptor type 3 (CR3, CD11b/CD18) regulate ligand avidity and the internalization of occupied receptors.

1993 • 47 citations

Characterization of a gain of function mutation of integrin alpha IIb beta 3 (platelet glycoprotein IIb-IIIa).

1992 • 43 citations

Differences in the binding of blocking anti-CD11b monoclonal antibodies to the A-domain of CD11b.

1995 • 13 citations